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Dr. Bob is Robert Hsiung, MD,
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Posted by PeterMartin on February 29, 2016, at 10:00:52
http://medicalxpress.com/news/2016-02-neuropeptide-depression-treatment.html
Innovative neuropeptide depression treatment to be developed
February 29, 2016
The Centre for Addiction and Mental Health (CAMH) and Impel NeuroPharma have signed a licensing agreement to advance a new neuropeptide-based therapeutic approach shown to be effective in treating depression.This novel treatment is a peptide that disrupts two dopamine receptors that bind at higher rates in the brains of people with major depression. This approach represents a first-in-class therapeutic for depression and potentially other conditions.
CAMH's Dr. Fang Liu, Senior Scientist and Head of Molecular Neuroscience in the Campbell Family Mental Health Research Institute, identified this elevated coupling of the D1 and D2 receptors in people with depression, and created the new peptide treatment. Dr. Liu then found a way to administer the peptide using the Precision Olfactory Delivery (POD) nasal delivery device developed by Impel NeuroPharma.[Continued in article]
Posted by Tomatheus on February 29, 2016, at 16:24:21
In reply to Neuropeptide depression treatment to be developed, posted by PeterMartin on February 29, 2016, at 10:00:52
Thank you for posting this. If this treatment ultimately gets approved and becomes available, I think that it would be one of the more innovative and unique medical treatments for depression that's come along in a while. There definitely seems to be a need for new depression treatments that act in ways that are different from the treatment options that are currently available, and the possibility that this treatment might have a more favorable side-effect profile than medications that are currently available definitely adds to its promise. Although this treatment is still a long way from becoming available if it ever becomes available, it's good to see treatment options that are innovative and rather unique being proposed for clinical development.
Tomatheus
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