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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by former poster on June 3, 2015, at 9:54:26
My Pdoc put me on 100mg X3 daily for anxiety and insomnia. A few hours after taking the first tablet I felt incredible benzo-like calm so profound that I went to a graduation party. I had very little appetite however. When I got home that evening I stood outside and looked around my yard and colors seemed to be more intense, pleasurable and my hearing was more acute. Nausea side effect was also unbearable. That night was the best sleep I have had in months. The next day still nausea and also diarrhea all day. Now I'm affraid to take another pill.
Posted by Lou Pilder on June 3, 2015, at 12:31:56
In reply to Topiramate sucess stories anyone?, posted by former poster on June 3, 2015, at 9:54:26
> My Pdoc put me on 100mg X3 daily for anxiety and insomnia. A few hours after taking the first tablet I felt incredible benzo-like calm so profound that I went to a graduation party. I had very little appetite however. When I got home that evening I stood outside and looked around my yard and colors seemed to be more intense, pleasurable and my hearing was more acute. Nausea side effect was also unbearable. That night was the best sleep I have had in months. The next day still nausea and also diarrhea all day. Now I'm affraid to take another pill.
f_p,
You wrote,[...My Pdoc put me on (Topamax) for anxiety and insomnia...].
The last time I looked at this drug it was illegal for it to be marketed by the drug company for psychiatric issues and was for seizure disorder and for migraine headaches. If this is still the case, then I would think that stopping the drug could be to your best interests. I also base this on knowing someone (an adult child of a friend of mind) who developed horrible adverse effects after taking the drug to the point where her mind was altered and could not succeed in graduate school. That is when I became interested in the drug's effects that I have found out that could be life-ruining.
If the drug is still illegal to be marketed by the drug company for psychiatric conditions, your prescriber could know of that. I do not know if it would be criminal or civil or both as to the liability that the Pdoc could be found or if you are entitled to damages. There are lawsuits involving the drug that have been settled and you could be one to enter a class action award. I do not know if the Pdoc is liable or just the drug company up to a certain date. It is my understanding that the Pdoc could prescribe off-label a drug that is illegal for the manufacture to market for what it is not approved for, but since there is a settled class action suit against the drug manufacturer, I do not know if that somehow changes that.
The overriding issue here is your health in relation to taking a drug that is not approved to take for psychiatric conditions, but just for epilepsy and to prevent migraine headaches. You are putting your trust on a Pdoc that is prescribing off-label if the drug is still only approved for epilepsy and migraine prevention. The Pdoc may be using you for an experiment without your consent since the drug is not approved for psychiatric conditions. And if the experimental use of the drug causes you to have a life-ruining condition, or sudden death, I am so sorry, my friend, for the Pdoc may be allowed to give you the drug legally. I think that is sad, really sad.
Lou
Posted by SLS on June 3, 2015, at 17:09:39
In reply to Topiramate sucess stories anyone?, posted by former poster on June 3, 2015, at 9:54:26
> My Pdoc put me on 100mg X3 daily for anxiety and insomnia.
That is a high dosage, particularly for a mood disorder. It is an extremely high dosage to initiate treatment with. You are most likely to develop cognitive and memory impairments unless you titrate gradually. I don't know why your doctor didn't start you off with 25 mg/day. The more gradually you titrate topiramate, the less likely you are to end up with cognitive impairments for the long-term.
I see no reason to go higher than 200 mg/day for topiramate. I have seen it help for hypomanic mixed-state and depression at 100 mg/day can work well for hypomania. 200 mg/day makes a good target. If you respond to that, you can try to reduce the dosage and see if you retain the therapeutic benefit at 100 mg/day. The risk of developing kidney stones (carbonic anhydrase inhibition) is dosage-dependent, so it is best to find the lowest effective dosage early in treatment.
I don't think that you should pass judgement on topiramate yet. However, I wouldn't take any more until you develop a plan to titrate the dosage properly. I would start at 25 mg/day. You could then go to 50 mg/day for a week and then to 100 mg/day. I actually went slower than this. At 200 mg/day, I didn't have the slightest worsening of cognitive and memory deficits.
http://www.ncbi.nlm.nih.gov/pubmed/11215835
At least follow the drug company's guidelines.
" Post-marketing data from physicians with clinical experience with TOPAMAX
have shown that slower titration improves tolerability and may reduce the rate
of discontinuation due to a lessening of side effects. The new dosing
schedule recommends that TOPAMAX be administered initially at 25-50 mg per
day, and titrated in increments of 25-50 mg per week until an effective daily
dose is reached.
"
- Scott
Posted by former poster on June 3, 2015, at 20:58:54
In reply to Re: Topiramate sucess stories anyone? » former poster, posted by SLS on June 3, 2015, at 17:09:39
Wow!
I stopped the Topiramate. It's been 48 hours since the the single dose I took and I'm just starting to get over the nausea. 24hrs after dosing I felt quite strange, nauseous and scary. Felt like my soul was dying or dead, with periods of calm. Now at 48 hrs I think I'm back to my old twitchy self again. These drugs are not to be taken lightly.
Lou you have a good point about stopping all meds. Profit is top priority with these drug companies and patient safety is a priority lost somewhere in deceit and slanted clinical trials.
Posted by Lou Pilder on June 3, 2015, at 22:04:15
In reply to Re: Topiramate sucess stories anyone? » SLS, posted by former poster on June 3, 2015, at 20:58:54
> Wow!
> I stopped the Topiramate. It's been 48 hours since the the single dose I took and I'm just starting to get over the nausea. 24hrs after dosing I felt quite strange, nauseous and scary. Felt like my soul was dying or dead, with periods of calm. Now at 48 hrs I think I'm back to my old twitchy self again. These drugs are not to be taken lightly.
> Lou you have a good point about stopping all meds. Profit is top priority with these drug companies and patient safety is a priority lost somewhere in deceit and slanted clinical trials.
>
f_p,
You wrote,[...Lou you have a good point about stopping all drugs...].
to be continued....
Lou
Posted by Lou Pilder on June 6, 2015, at 18:52:52
In reply to Lous reply-2Bkuntynyewd » former poster, posted by Lou Pilder on June 3, 2015, at 22:04:15
> > Wow!
> > I stopped the Topiramate. It's been 48 hours since the the single dose I took and I'm just starting to get over the nausea. 24hrs after dosing I felt quite strange, nauseous and scary. Felt like my soul was dying or dead, with periods of calm. Now at 48 hrs I think I'm back to my old twitchy self again. These drugs are not to be taken lightly.
> > Lou you have a good point about stopping all meds. Profit is top priority with these drug companies and patient safety is a priority lost somewhere in deceit and slanted clinical trials.
> >
> f_p,
> You wrote,[...Lou you have a good point about stopping all drugs...].
> to be continued....
> LouFriends,
The poster says that I have a good point in stopping all drugs. But what more, the poster writes concerning the degree of concern for the safety of those taking the drugs in relation to the profit that the drug companies can make by using deceit and slanted clinical trials.
The Earth is the house of humanity. And when one puts profit above humanity, they make the house a house of merchandise. You see, there is a Great Deception to humanity that has been revealed to me. I am prevented from posting that here due to the prohibitions posted to me here by Mr. Hsiung and his wishes carried out by any deputy of his. But as long as profit is held above humanity, the Great Deception will increase the profits until the money changers are driven out.
Let no man deceive you. For there will men saying that you have a chemical imbalance and exchange your suffering for money, making you think that you have to pay them to get the drugs to correct the balance. But is there any evidence of that? And do not the drugs create a chemical imbalance so that you could get tardive dyskinesia and addiction and heart attack and stroke and diabetes and a long list of life-ruining conditions and death?
I could post here what I think could save lives if it was for Mr. Hsiung's prohibitions posted to me here. I could even post a way for those that want to be free from all drugs to be delivered from the bondage of the drugs. But I am prohibited and it is sad, very sad.
The blood of those here that were killed by the drugs or killed themselves will not be upon me.
Lou
Posted by former poster on June 7, 2015, at 12:03:40
In reply to Lou's reply-monycheyngerz, posted by Lou Pilder on June 6, 2015, at 18:52:52
Lou, I know exactly what you are talking about.
This "great deception" was revealed to me also. I was shocked, relieved it wasn't just my imagination when I learned of it. But life goes on..The meds that are available are a mix of good, bad, and ugly ...Mostly bad and ugly.
Severe seizures need to be treated with medication. Mental illness is just another spectrum of the same.
Hopefully those suffering will find the right agent. We can only try to help guide them with our knowledge and experience to avoid the bad ones.
Posted by Lou Pilder on June 7, 2015, at 15:50:13
In reply to Re: Lou's reply-monycheyngerz » Lou Pilder, posted by former poster on June 7, 2015, at 12:03:40
> Lou, I know exactly what you are talking about.
> This "great deception" was revealed to me also. I was shocked, relieved it wasn't just my imagination when I learned of it. But life goes on..
>
> The meds that are available are a mix of good, bad, and ugly ...Mostly bad and ugly.
> Severe seizures need to be treated with medication. Mental illness is just another spectrum of the same.
> Hopefully those suffering will find the right agent. We can only try to help guide them with our knowledge and experience to avoid the bad ones.f_p,
The revelation that I am referring to could be vastly different from yours.
What has been revealed to me comes from a Jewish perspective that is prohibited by Mr. Hsiung for me to post here.
Lou
Posted by former poster on June 8, 2015, at 11:42:23
In reply to Re: Topiramate sucess stories anyone? » SLS, posted by former poster on June 3, 2015, at 20:58:54
..."Felt like my soul was dying or dead"...
I'd like to re-phrase that. The feeling was more like I was "slipping into a coma, or in a coma" after that I had a feeling of confusion and coming unraveled.
I recall a similar episode 20 years ago when my GP put me on Triazolam while on xanax. I stopped the Triazolam and slowly returned to normal.
Is this considered a psychotic reaction/episode? I didn't think any harm could come taking 1 Topamax tablet.
It's been a week since I took the 100mg Topiramate. Now I'm feeling 95% normal but have this sense of dread that the feeling could come back. Afraid it may have destabilized me.
Time to go back on Clonazepam.
I'd really appreciate some comments advice or support. Lou, your comment didn't help at all.Phillipa, you out there?
Posted by Lou Pilder on June 8, 2015, at 13:58:44
In reply to Re: Topiramate hell. » former poster, posted by former poster on June 8, 2015, at 11:42:23
> ..."Felt like my soul was dying or dead"...
>
> I'd like to re-phrase that. The feeling was more like I was "slipping into a coma, or in a coma" after that I had a feeling of confusion and coming unraveled.
>
> I recall a similar episode 20 years ago when my GP put me on Triazolam while on xanax. I stopped the Triazolam and slowly returned to normal.
> Is this considered a psychotic reaction/episode? I didn't think any harm could come taking 1 Topamax tablet.
> It's been a week since I took the 100mg Topiramate. Now I'm feeling 95% normal but have this sense of dread that the feeling could come back. Afraid it may have destabilized me.
> Time to go back on Clonazepam.
> I'd really appreciate some comments advice or support. Lou, your comment didn't help at all.
>
> Phillipa, you out there?
>
f_p,
You wrote,[...Lou, your comment didn't help at all...].
I am unsure as to what comment you are referring to by me as to what you are wanting readers or myself to think about me. If you could post answers to the following, then I could have the opportunity to respond accordingly.
A. Which comment by me are you referring to?
B. Why was that comment not helpful at all?
C. Could the comment be helpful to some other reader? If not, why not?
D. Do you think that by the fact that the comment is not specified, that I could be stigmatized by what you wrote about me here?
Lou
This is the end of the thread.
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