Psycho-Babble Medication Thread 1069838

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LY2140023.For Schizophrenia.

Posted by Lamdage22 on August 15, 2014, at 13:41:59

Glutamate receptor targeting drug. Pipeline.

http://www.drugdevelopment-technology.com/projects/elililleyantisycotic/

 

Re: LY2140023.For Schizophrenia.

Posted by Lamdage22 on August 15, 2014, at 13:52:29

In reply to LY2140023.For Schizophrenia., posted by Lamdage22 on August 15, 2014, at 13:41:59

http://en.wikipedia.org/wiki/ALKS-5461

 

Re: LY2140023.For Schizophrenia.

Posted by Lamdage22 on August 15, 2014, at 13:57:04

In reply to Re: LY2140023.For Schizophrenia., posted by Lamdage22 on August 15, 2014, at 13:52:29

Again, check out "see also"

 

Re: LY2140023.For Schizophrenia.

Posted by jrbecker76 on August 19, 2014, at 11:16:01

In reply to Re: LY2140023.For Schizophrenia., posted by Lamdage22 on August 15, 2014, at 13:57:04

> Again, check out "see also"

Unfortunately, this drug (aka Pomaglumetad methionil) failed to find significant findings in Ph III trials and is more than likely abandoned. There actually was some interesting data from the trial that showed that a subgroup of patients with a particular genotypic biomarker for the 5-HT2a receptor did particularly well with it. But I'm not sure Lilly is still pursuing it. They might still be looking at this class for Bipolar d/o though.



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