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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by vbs on December 18, 2013, at 0:50:35
Hi fellow babblers, I'm wondering what other anti-psychotic meds I could try. I have schizoaffective disorder & currently take the following:
Zyprexa 20 mg
Invega Sustenna injection
Cymbalta, 60 mgThe problem is that I'm still hearing voices a lot. My pdoc & I want 2 try swapping out the Zyprexa for something else at my next appointment in a month. I've tried & failed Seroquel & Risperdal. Also taken Haldol which I had to discontinue due to akathesia.
What other APs might work? I'm really frustrated.
Thanks for reading.
Posted by SLS on December 18, 2013, at 1:27:49
In reply to At a dead end - options?, posted by vbs on December 18, 2013, at 0:50:35
> Hi fellow babblers, I'm wondering what other anti-psychotic meds I could try. I have schizoaffective disorder & currently take the following:
>
> Zyprexa 20 mg
> Invega Sustenna injection
> Cymbalta, 60 mg
>
> The problem is that I'm still hearing voices a lot. My pdoc & I want 2 try swapping out the Zyprexa for something else at my next appointment in a month. I've tried & failed Seroquel & Risperdal. Also taken Haldol which I had to discontinue due to akathesia.
>
> What other APs might work? I'm really frustrated.
>
> Thanks for reading.
Navane (thiothixene)?Navane is not as harsh as Haldol. I can't guarantee that you won't experience akathisia, but it is an effective drug for schizoaffective disorder when the atypicals alone are inadequate.
Do you think that Cymbalta is making things worse? I wonder if this drug might make akathisia worse.
Latuda and Saphris are worth a look. Both have antidepressant properties and can be combined with other antipsychotics. Look at using Navane in combination with an atypical antipsychotic (other than risperidone).
* Seroquel
* Abilify
* Latuda
* Saphris
- Scott
Posted by vbs on December 18, 2013, at 2:04:05
In reply to Re: At a dead end - options? » vbs, posted by SLS on December 18, 2013, at 1:27:49
Scott, thanks for replying. I forgot to mention that I've already tried Saphris. It didn't really do much for me. There was a time when I was taking three anti psychotic meds - Zyprexa, Saphris & Invega Sustenna.
Peace.
Posted by Jeroen on December 18, 2013, at 2:59:21
In reply to Re: At a dead end - options? » SLS, posted by vbs on December 18, 2013, at 2:04:05
try
Posted by vbs on December 18, 2013, at 4:16:51
In reply to Re: At a dead end - options? » vbs, posted by SLS on December 18, 2013, at 1:27:49
I don't think Cymbalta is aggravating my condition as it doesn't affect dopamine levels. I'll talk to my pdoc about this possibility.
Posted by vbs on December 18, 2013, at 4:20:56
In reply to abilify kills voices, posted by Jeroen on December 18, 2013, at 2:59:21
Thanks, Jeroen. I'll mention Abilify to my pdoc.
Posted by SLS on December 18, 2013, at 7:09:50
In reply to abilify kills voices, posted by Jeroen on December 18, 2013, at 2:59:21
> try
Didn't Christ_Empowered find the same thing?
- Scott
Posted by Phillipa on December 18, 2013, at 9:17:25
In reply to At a dead end - options?, posted by vbs on December 18, 2013, at 0:50:35
Hi VBS I'm sorry you are having these problems. What's you Dad say or no opinion? Phillipa
Posted by Jeroen on December 18, 2013, at 10:28:28
In reply to Re: At a dead end - options? » vbs, posted by Phillipa on December 18, 2013, at 9:17:25
just be carefull but abilify is my emergency med for years now
Posted by ed_uk2010 on December 18, 2013, at 14:16:30
In reply to At a dead end - options?, posted by vbs on December 18, 2013, at 0:50:35
> Hi fellow babblers, I'm wondering what other anti-psychotic meds I could try. I have schizoaffective disorder & currently take the following:
>
> Zyprexa 20 mg
> Invega Sustenna injection
> Cymbalta, 60 mg
>
> The problem is that I'm still hearing voices a lot.In schizophrenia, where multiple antipsychotics have proved to be ineffective, only clozapine (Clozaril) has been demonstrated to be reliably useful in terms of reducing hallucinations/delusions and improving functioning. The same may apply to schizoaffective disorder.
You could of course try a merry-go-round of other antipsychotics, but quite frankly I would consider clozapine if your hallucinations are still frequent and disturbing.
You may find the side effects of clozapine to be rather similar to the high dose of Zyprexa that you currently take, except than increased salivation is a common problem with clozapine, often requiring an additional med to reduce this. The need for frequent blood tests is unfortunate, but they almost always come back normal. Dizziness, drowsiness, dyspepsia and constipation are common with clozapine, but can usually be dealt with. Treatment is often optimised by measuring the clozapine blood level. This is useful for patients who do not appear to be responding to normal doses. In this situation, increasing the dose without checking the clozapine level can cause a seizure if the blood level is already high. On average, men tend to require slightly higher doses than women. Smokers usually require substantially higher doses than non-smokers.
Clozapine is annoying.... blood tests, monitoring, cautious dose adjustments, risk of side effects etc. The main advantage is that it works.
Posted by SLS on December 18, 2013, at 14:48:49
In reply to Re: At a dead end - options? » vbs, posted by ed_uk2010 on December 18, 2013, at 14:16:30
Posted by vbs on December 18, 2013, at 15:31:00
In reply to Re: At a dead end - options? » vbs, posted by ed_uk2010 on December 18, 2013, at 14:16:30
Yeah my pdoc mentioned Clozaril at our last appointment. He doesn't want to try it because of the required blood tests.
Posted by Jeroen on December 18, 2013, at 16:10:35
In reply to Re: At a dead end - options? » vbs, posted by ed_uk2010 on December 18, 2013, at 14:16:30
are you still [xxx]?
i wanna order some minocycline online how do i know its real?
Posted by Phillipa on December 18, 2013, at 21:06:09
In reply to Re: At a dead end - options? » ed_uk2010, posted by vbs on December 18, 2013, at 15:31:00
VBS honestly I saw miracles occur with this med. patients were inpatient at the time. Very tired in the beginning and takes a while but it worked so many times while others had failed. Phillipa
Posted by ed_uk2010 on December 20, 2013, at 15:28:22
In reply to to eduk, posted by Jeroen on December 18, 2013, at 16:10:35
>i wanna order some minocycline online how do i know its real?
Any site which supplies meds without a prescription is likely to sell fakes. Over here, registered online pharmacies will always display their registration number, which can be checked. I do not know how this works in your country though.
Posted by ed_uk2010 on December 20, 2013, at 15:30:04
In reply to Re: At a dead end - options? » ed_uk2010, posted by vbs on December 18, 2013, at 15:31:00
>He doesn't want to try it because of the required blood tests.
There are plenty of other meds you can try. They may be more convenient and some may cause fewer adverse effects. Unfortunately, they are also less likely to be effective. Difficult decisions...
Posted by Jeroen on December 21, 2013, at 9:40:43
In reply to Re: At a dead end - options? » vbs, posted by ed_uk2010 on December 20, 2013, at 15:30:04
thanks for the warning
This is the end of the thread.
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