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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by Prefect on November 3, 2012, at 22:32:13
Do you know much about the research on this phenomenon?
I've been taking Luvox at 50 mg for 7 years for Panic and Agoraphobia and 25 mg for 7 years prior to that for strange somatic symptoms. I'm in the process of raising my dose to 75 mg (and possibly 100 mg)for a relapse I'm going through.
This puts me at about 14 years in total so far. Does this means I have untreatable Major Depression to look forward to because my brain will gradually downregulate my receptors to compensate for over abondance of serotonin produced by the medication? Or in my case would it be a severe case of what I have now? Can this happen at the dosage I'm taking? Has this phenomenon been proven? Pretty scary.
Posted by poser938 on November 3, 2012, at 22:52:22
In reply to Tardive Disphoria..., posted by Prefect on November 3, 2012, at 22:32:13
> Do you know much about the research on this phenomenon?
>
> I've been taking Luvox at 50 mg for 7 years for Panic and Agoraphobia and 25 mg for 7 years prior to that for strange somatic symptoms. I'm in the process of raising my dose to 75 mg (and possibly 100 mg)for a relapse I'm going through.
>
> This puts me at about 14 years in total so far. Does this means I have untreatable Major Depression to look forward to because my brain will gradually downregulate my receptors to compensate for over abondance of serotonin produced by the medication? Or in my case would it be a severe case of what I have now? Can this happen at the dosage I'm taking? Has this phenomenon been proven? Pretty scary.I havent researched it much for when this problem is caused by serotonin increasing meds.
In my situation I have been looking in to meds tht disinhibit dopamine release. It seemeds tht Mirapex gave me an abundance of dopamine stimulation that was unnatural.
There are certain receptors that work to inhibit dopasmine, such as the serotonin 2C receptor. I believe this is why Cyproheptadine helped me so much.I'm unsure about whast receptors in the brain work to inhibit serotonin release, maybe someone on here has more knowledge in this.
Posted by phillipa on November 3, 2012, at 23:23:22
In reply to Tardive Disphoria..., posted by Prefect on November 3, 2012, at 22:32:13
Perfect since I've also been on luvox first 25mg and now the 50mg for about the same amount of time. I guess I best do some reasearch. I have my own theory that if serotonin Is in the is it snyaptic cleft for long as is the case with serotonin meds that the brain figures why produce it anymore. In other words "hey someone is making life easier for me" So like insulin your brain needs it to remain in equalibrium. Now this Tardive Dysphoria. I will research. Probably have it myself. Phillipa
Posted by phillipa on November 3, 2012, at 23:28:20
In reply to Re: Tardive Disphoria... » Prefect, posted by phillipa on November 3, 2012, at 23:23:22
http://www.bmedreport.com/archives/24298
This is why I will not up my dose. Phillipa
Posted by jono_in_adelaide on November 4, 2012, at 5:25:15
In reply to Re: Tardive Disphoria..., posted by poser938 on November 3, 2012, at 22:52:22
I'd say its very far from being proven - its more an outlandish theory at the moment, and nothing more
Posted by Lou Pilder on November 4, 2012, at 6:59:20
In reply to Re: Tardive Disphoria..., posted by jono_in_adelaide on November 4, 2012, at 5:25:15
> I'd say its very far from being proven - its more an outlandish theory at the moment, and nothing more
j,
You wrote the above,
I am unsure as to what criteria you use to substantiate, if that is what you are attempting here to do, that tardive dysphoria is an {outlandish} theory. If you could list those criteria, if any, then I could have the opportunity to respond accordingly.
Lou
Posted by jono_in_adelaide on November 4, 2012, at 18:08:12
In reply to Lou's response-owltlhan » jono_in_adelaide, posted by Lou Pilder on November 4, 2012, at 6:59:20
Monoamine reuptake inhibitors have been in widespread use for 50 years, yet "tardive dysphoria" has only been suggested by 1 or 2 minor research teams very recently, if it occurs at all, its extremely rare.
You are far more likely to be killed in a car accident that suffer tasrdive dysphoria from an antiderpessant prescribed for a serious illness.
My advice would be avoid antidepressants for mild situational depression, where their benifits are unclear, but keep using them for moderate severe depression, where their benifits are clear cut.
Posted by poser938 on November 4, 2012, at 18:52:13
In reply to Re: Lou's response-owltlhan, posted by jono_in_adelaide on November 4, 2012, at 18:08:12
You are far more likely to be killed in a car accident on the way to play the lottery thsn you are to win. But people know winning it is very well possible, so millions play it every day.
Posted by jono_in_adelaide on November 5, 2012, at 0:31:23
In reply to Re: Lou's response-owltlhan, posted by poser938 on November 4, 2012, at 18:52:13
Or, choose not to take them at all, and either live a life of abject misery, or die by your own hand.
Posted by Lou PIlder on November 5, 2012, at 21:01:43
In reply to Re: Lou's response-owltlhan, posted by jono_in_adelaide on November 5, 2012, at 0:31:23
> Or, choose not to take them at all, and either live a life of abject misery, or die by your own hand.
>
> J,
You wrote the above. So as to not have the readers think otherwise, could you post answers to the following?
A. Could there be the possibility that if one does not take mind-altering drugs, they could have life and life more abundantly?
B. Are the choices that you posted the only choices for one in depression?
C. Can people kill themselves while taking psychotropic druigs?
D. Can people get a life-ruining condition from taking psychotropic drugs?
E. Are you aware that many psychotropic drugs are addicting in that if stopped a withdrawal that can be horrific can happen including suicide or homocide?
F. Are you aware of the fallacy called {false dilemma}?
Lou
This is the end of the thread.
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