![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by 4WD on September 29, 2012, at 9:47:29
I discovered this by accident. I used to take Nuvigil for chronic fatigue. When it would start wearing off, I'd feel horrible, sick, depressed, scared etc. Fur some reason I tried taking a small dose if bedtime meds: 25-50mg Trazadone, 20 mg Geodon, .25-.5 of Klonopin. Within 30 minutes, all the bad stuff would go away. Also tried it when feeling very bad on waking and it helped. Now, on Parnate, when I feel horrible from the previous nights insomnia on top of as Parnate fatigue, it helps that to o. I'm pretty sure its the Trazadone doing it-I've tried it with just the Klonopin our Geodon and no help from that. Anybody want to hazard a guess? And BTW you can take Trazadone w/MAOI-I took 100-200 mg a might for three years on Nardil and no with it now either.
Posted by phillipa on September 29, 2012, at 10:13:27
In reply to when feeling really bad, why does Trazadone help?, posted by 4WD on September 29, 2012, at 9:47:29
No idea do that many take trazadone anymore? Haven't seen it mentioned in a long time. Hows the parnate going? Phillipa
Posted by phillipa on September 29, 2012, at 10:19:58
In reply to when feeling really bad, why does Trazadone help?, posted by 4WD on September 29, 2012, at 9:47:29
Google lists it as being like serzone. But does also say contraindicated with Maios? And you took it with Nardil? Phillipa
Posted by 4WD on September 29, 2012, at 12:04:36
In reply to Re: when feeling really bad, why does Trazadone help? » 4WD, posted by phillipa on September 29, 2012, at 10:19:58
> Google lists it as being like serzone. But does also say contraindicated with Maios? And you took it with Nardil? Phillipa
I read that it was such a weak serotonergic agent that it want likely to be a problem. And my old p doc was a super genius with needs and he prescribed them both-out me in z Nardil when I asked and didn't take me off Trazadone. But Pi duo take s low dose if it, just half it even a quarter of a 100 mg pill. But my new p doc is kind of a wuss that way. When pi went on Parnate he says I'd have to stop the Trazadone. I just kept quiet and kept taking it. I'll tell him at my next appt snout the Nardil plus Traz and the Parnate plus Traz add a dine deal and what can he say? But I feel pretty sure he'd never even consider letting me take a stimulant with it for the daytime fatigue and sleepiness I'm having such a problem with. I take 20 mg when I get up and (after an hour or so up) then in about an hour I start having a little energy. Then I usually have 3-4 good hours when I feel good-normal good. Then it wears if and even though I take a second dose, I'm so tired and sleepy starting about 3 our 4 pm that I'm no guid for anything the rest if the day. But yesterday might I tried the Trazadone/Geodon combo and after about an hour I felt at least decent again. Though I did fall asleep on the couch till 2am and couldn't wake up enough to go to bed till then.
Posted by 4WD on September 29, 2012, at 12:08:22
In reply to Trazadone (with Parnate) and how Parnate's doing, posted by 4WD on September 29, 2012, at 12:04:36
I apologize for the typos. I'm on my mobile phone and it chooses words for me-predictive text-that are not what I intended. And I can't always see all if what I'm typing.
Marsha
Posted by phidippus on September 29, 2012, at 17:29:05
In reply to when feeling really bad, why does Trazadone help?, posted by 4WD on September 29, 2012, at 9:47:29
Trazadone is a 5-HT1A partial agonist, which helps with anxiety. Its primary mechanism of action is as a 5-HT2A receptor antagonism. Antagonizing this receptor also reduces anxiety.
Eric
Posted by 4WD on October 2, 2012, at 12:10:25
In reply to Re: when feeling really bad, why does Trazadone help? » 4WD, posted by phidippus on September 29, 2012, at 17:29:05
> Trazadone is a 5-HT1A partial agonist, which helps with anxiety. Its primary mechanism of action is as a 5-HT2A receptor antagonism. Antagonizing this receptor also reduces anxiety.
>
> Eric
Thank you. I knew it was related more to the 5HT receptor action than to any Ssri action-the effect was so immediate-25-35 minutes after dosing If feel so much better. And I strict the Geodon-Trazadone combination is a part if it, asking with a scrap of a Klonopin, 1/4mg it leads.
Thanks for your answer
Posted by phidippus on October 2, 2012, at 17:49:50
In reply to Re: when feeling really bad, why does Trazadone help? » phidippus, posted by 4WD on October 2, 2012, at 12:10:25
What are all your meds?
Eric
Posted by 4WD on October 3, 2012, at 15:55:07
In reply to Re: when feeling really bad, why does Trazadone help? » 4WD, posted by phidippus on October 2, 2012, at 17:49:50
Oh Lord, let's see.
Am- 2mg estradiol, 20mg Geodon, 1/3 Prevacid and recently added Parnate, 10 mg t.i.d.
Afternoon sometimes 20mg more GeodonBedtime: 25-50 mg Trazadone, 1/4 - 1/2mg Klonopin, 1/2 pepcid (half a40 mg tab), 40 mg Geodon. Sometimes add 50-75 mg Lyrica
Also, as needed, 1/4 mg Xanax for panic attacks. And for episodes if intense severe depression, 2.5 Zyprexa. I also take prometrium-the counterpart to the morning estrogen.
I'm doing ok on Parnate except for hypotension and tiredness.
I've recently stopped Nuvigil and/or Adderall but consisting resuming a small dose of the latter for the Parnate exhaustion.
Posted by 4WD on October 3, 2012, at 16:38:52
In reply to Re: when feeling really bad, why does Trazadone help?, posted by 4WD on October 3, 2012, at 15:55:07
> I'm on a lot of meds but all if them are small to minute dosages. I was higher dissed but some GP told me the reason I was always so lethargic and apathetic and tired was because I was on "so much medication."
Oh Lord, let's see.
> Am- 2mg estradiol, 20mg Geodon, 1/3 Prevacid and recently added Parnate, 10 mg t.i.d.
> Afternoon sometimes 20mg more Geodon
>
> Bedtime: 25-50 mg Trazadone, 1/4 - 1/2mg Klonopin, 1/2 pepcid (half a40 mg tab), 40 mg Geodon. Sometimes add 50-75 mg Lyrica
>
> Also, as needed, 1/4 mg Xanax for panic attacks. And for episodes if intense severe depression, 2.5 Zyprexa. I also take prometrium-the counterpart to the morning estrogen.
>
> I'm doing ok on Parnate except for hypotension and tiredness.
>
> I've recently stopped Nuvigil and/or Adderall but consisting resuming a small dose of the latter for the Parnate exhaustion.
>
Posted by phillipa on October 3, 2012, at 22:55:28
In reply to Re: when feeling bad... for Phippidus mostly, posted by 4WD on October 3, 2012, at 16:38:52
Careful with the providgil? Phillipa
Posted by 4WD on October 4, 2012, at 0:04:40
In reply to Re: when feeling really bad, why does Trazadone help? » 4WD, posted by phidippus on September 29, 2012, at 17:29:05
> Trazadone is a 5-HT1A partial agonist, which helps with anxiety. Its primary mechanism of action is as a 5-HT2A receptor antagonism. Antagonizing this receptor also reduces anxiety.
>
> Eric
Thank you. I knew it was related more to the 5HT receptor action than to any Ssri action-the effect was so immediate-25-35 minutes after dosing If feel so much better. And I strict the Geodon-Trazadone combination is a part if it, asking with a scrap of a Klonopin, 1/4mg it leads.
Thanks for your answer
Posted by phidippus on October 4, 2012, at 16:54:21
In reply to Re: when feeling bad... for Phippidus mostly, posted by 4WD on October 3, 2012, at 16:38:52
What's the Geodon helping you with?
What do you use the Lyrica for?
You're only on 10 mg of Parnate?
Eric
Posted by 4WD on October 5, 2012, at 4:04:08
In reply to Re: when feeling bad... for Phippidus mostly » 4WD, posted by phidippus on October 4, 2012, at 16:54:21
> What's the Geodon helping you with?
>
> What do you use the Lyrica for?
>
> You're only on 10 mg of Parnate?
> www
> EricOh, forgot. Also on buprenorphine 16mg day. Tapering off it very slowly.
On the a Geodon because when I first went in it in 2008, I achieved complete remission overnight (as an adjunct to Nardil). It actually pooped out eventually but I get more anxiety w/0 it.. Scared to let it go I guess.No, 30mg Parnate. 10mg x 3/day.
Lyrica was Rxd for fibromyalgia years ago. Its not a regular med,, take it only when I need to try and sleep longer.
Trazadone helped to keep me from waking up too early panicky. Not sure what its doing now.
Klonopin helps as an a/d more than an anxiolytic .
Could 1/4s of the Trazadone 100mg and Klonopin 1mg plus 20-40mg Geodon at bedtime cause me to wake top every day feeling like jet lag plus bad flu plus the worst hangover anyone had ever had? Thus feeling lasts 4 hours or so after waking. I sometimes sleep 12-14 hours and then still need a nap later. But if I wake up early our earlier, I feel horrible all day, not just at first.
At wits end. I can only stand the mornings because there is no other choice. But I wake up sick and miserable and totally dysfunctional for half the . Day. The b first 2-3 hours I can't even bear to open my eyes. I just sit on the couch and somehow tolerate it.
My pdoc is not a real creative thinker. These are the meds my previous odoc put me on 5-6 years ago. The current one doesn't ever suggest anything or changes. I have to come up with my own treatment plan. I suggested the Parnate. I reduced the dosages if thebedtime meds.
Posted by phidippus on October 5, 2012, at 15:51:56
In reply to Re: when feeling bad... for Phippidus mostly » phidippus, posted by 4WD on October 5, 2012, at 4:04:08
>Oh, forgot. Also on buprenorphine 16mg day. Tapering off it very slowly.
Why?
>Scared to let it go I guess.
This is a poor excuse to keep taking a medication. Is their any way you can try life without it?
>take it only when I need to try and sleep longer
Gabitril helps more with sleep, improving stage 4 sleep.
>Not sure what its doing now
Trazadone is probably helping with anxiety. You're taking too low a dose to get an antidepressant effect.
>Could 1/4s of the Trazadone 100mg and Klonopin >1mg plus 20-40mg Geodon at bedtime cause me to >wake top every day feeling like jet lag
It certainly could. Do you have bad insomnia?
Eric
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.