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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 19 of 19. This is the beginning of the thread.
Posted by Exister on August 13, 2012, at 17:06:32
After 3+ yrs on Marplan and with litle success, looks like im going back to Nardil. Tho I'm trying one last go- despite being on Seroquel before, i was on other stuff too (Valdoxan, Trimipramine, bupropion, clonazepam, Abilify, Solian all within a year and in various combos). Now I've restarted Seroquel with just the Marplan, clonazepam and the bupropion. I figure it best to keep the bupropion as it is one AD to be proven to successfully be augmented by Seroquel.
Surprisingly I feel better from just a small 25mg afternoon dose followed by a short sleep.
Soz for the mix in Brands & generics!
Wish me luck,Ex
Posted by Tomatheus on August 13, 2012, at 18:21:38
In reply to Thats long enough!, posted by Exister on August 13, 2012, at 17:06:32
Hi Exister, and welcome to Psycho-Babble.
So, it sounds like your plan is to take Nardil, clonazepam, and bupropion, with Seroquel. Is this correct? What is it that you're treating?
No matter what condition you're receiving treatment for, I wish you luck with your switch from Marplan to Nardil. May you receive relief from what you're suffering from.
Tomatheus
Posted by Exister on August 13, 2012, at 18:32:06
In reply to Re: Thats long enough!, posted by Tomatheus on August 13, 2012, at 18:21:38
> Hi Exister, and welcome to Psycho-Babble.
>
> So, it sounds like your plan is to take Nardil, clonazepam, and bupropion, with Seroquel. Is this correct? What is it that you're treating?
>
> No matter what condition you're receiving treatment for, I wish you luck with your switch from Marplan to Nardil. May you receive relief from what you're suffering from.
>
> Tomatheusyes thats right, Seroquel (increase from 25-100mg), Marplan (120mg), Klonopin (4mg), Wellbutrin (300mg).
Social phobia & major depression are my ills.
Thanx for the comment
Ex
Posted by Exister on August 13, 2012, at 18:34:58
In reply to Re: Thats long enough! » Tomatheus, posted by Exister on August 13, 2012, at 18:32:06
Sorry thats not quite clear, I will change to Nardil if this next idea fails.
Posted by Tomatheus on August 13, 2012, at 18:48:51
In reply to Re: Thats long enough! » Exister, posted by Exister on August 13, 2012, at 18:34:58
> Sorry thats not quite clear, I will change to Nardil if this next idea fails.
Ok, makes sense. Again, good luck!
Tomatheus
Posted by Lou Pilder on August 13, 2012, at 21:12:54
In reply to Re: Thats long enough! » Tomatheus, posted by Exister on August 13, 2012, at 18:32:06
> > Hi Exister, and welcome to Psycho-Babble.
> >
> > So, it sounds like your plan is to take Nardil, clonazepam, and bupropion, with Seroquel. Is this correct? What is it that you're treating?
> >
> > No matter what condition you're receiving treatment for, I wish you luck with your switch from Marplan to Nardil. May you receive relief from what you're suffering from.
> >
> > Tomatheus
>
> yes thats right, Seroquel (increase from 25-100mg), Marplan (120mg), Klonopin (4mg), Wellbutrin (300mg).
>
> Social phobia & major depression are my ills.
>
> Thanx for the comment
> ExEx,
You wrote the above.
The drugs that you are taking could kill you. You see, there are 3 of the 4 that are central nervous system depressants and respiratory depressants. When combined, they could have a geometric effect of suppression and death could happen. Not only that, but taking the drugs together can induce seizures. And on top of that, the drugs can induce a state where you could be compelled to kill yourself and/or others and if you stop the drugs, you could go into a state where people kill themselves and/or others.
Now I have some questions thht if you post anserws to them here, I could have the opportunity to post a response to you.
A. What kind of prescriber, if there is one, gives you all of these drugs to take together?
B. If one prescriber does not prescribe all of these drugs to you to take together, where do you obtain the drugs?
C. Have you looked up the prescriber's name in a registry of doctors that have been (redacted by respondent)
D. Have you found out if any of the prescriber's clients (redated by respondent)
E. What makes you believe, if you do believe, that taking all those drugs together is safe, if you believe that?
Lou
Posted by Phillipa on August 13, 2012, at 23:28:06
In reply to Re: Thats long enough! » Exister, posted by Exister on August 13, 2012, at 18:34:58
Best of luck!!!! Phillipa
Posted by SLS on August 14, 2012, at 1:07:46
In reply to Thats long enough!, posted by Exister on August 13, 2012, at 17:06:32
> After 3+ yrs on Marplan and with litle success, looks like im going back to Nardil. Tho I'm trying one last go- despite being on Seroquel before, i was on other stuff too (Valdoxan, Trimipramine, bupropion, clonazepam, Abilify, Solian all within a year and in various combos). Now I've restarted Seroquel with just the Marplan, clonazepam and the bupropion. I figure it best to keep the bupropion as it is one AD to be proven to successfully be augmented by Seroquel.
> Surprisingly I feel better from just a small 25mg afternoon dose followed by a short sleep.
> Soz for the mix in Brands & generics!
> Wish me luck,
>
> ExI have personally witnessed a young woman experience an immediate and robust antidepressant effect after taking just one 50 mg dose of Seroquel. She felt great and functioned much better within three days of continued treatment. She was taking Wellbutrin and risperidone at the time. Once risperidone was discontinued and replaced by Abilify, the dosage of Seroquel needed to be brought up as high as 800 mg/day in order to control her symptoms. My guess is that Abilify outcompetes Seroquel for dopamine receptor binding sites on the postsynaptic membrane and thereby inhibits through partial agonism the antipsychotic actions of Seroquel.
- Scott
Posted by jono_in_adelaide on August 14, 2012, at 1:33:33
In reply to Re: Thats long enough! » Exister, posted by SLS on August 14, 2012, at 1:07:46
Scott - i got a similar effect from one dose of risperidone - I took 1mg at bedtime, and work up the next morning feeling less anxious, less depressed and less full of doom.
I was taking sertaline, reboxetine and alprazolam already
Posted by Exister on August 20, 2012, at 11:01:53
In reply to Thats long enough!, posted by Exister on August 13, 2012, at 17:06:32
Well I'm still only on 50mg Seroquel. Apart from a false start, where I felt great for 24hrs I now feel no benefits. Today I will go to 100mg, see if that helps. If it does, although im running outa pills i can restock soon and then maybe up the dose. But I have a strong suspision that Nardil is needed in place of Marplan. That means coming off everything (except maybe klonopin) AND 2 weeks clean untill I can start it. I'm still very depressed & I'm preparing for hell on earth!
Posted by Exister on August 20, 2012, at 11:14:18
In reply to Lou's warning-aflac » Exister, posted by Lou Pilder on August 13, 2012, at 21:12:54
> > > Hi Exister, and welcome to Psycho-Babble.
> > >
> > > So, it sounds like your plan is to take Nardil, clonazepam, and bupropion, with Seroquel. Is this correct? What is it that you're treating?
> > >
> > > No matter what condition you're receiving treatment for, I wish you luck with your switch from Marplan to Nardil. May you receive relief from what you're suffering from.
> > >
> > > Tomatheus
> >
> > yes thats right, Seroquel (increase from 25-100mg), Marplan (120mg), Klonopin (4mg), Wellbutrin (300mg).
> >
> > Social phobia & major depression are my ills.
> >
> > Thanx for the comment
> > Ex
>
> Ex,
> You wrote the above.
> The drugs that you are taking could kill you. You see, there are 3 of the 4 that are central nervous system depressants and respiratory depressants. When combined, they could have a geometric effect of suppression and death could happen. Not only that, but taking the drugs together can induce seizures. And on top of that, the drugs can induce a state where you could be compelled to kill yourself and/or others and if you stop the drugs, you could go into a state where people kill themselves and/or others.
> Now I have some questions thht if you post anserws to them here, I could have the opportunity to post a response to you.
> A. What kind of prescriber, if there is one, gives you all of these drugs to take together?
> B. If one prescriber does not prescribe all of these drugs to you to take together, where do you obtain the drugs?
> C. Have you looked up the prescriber's name in a registry of doctors that have been (redacted by respondent)
> D. Have you found out if any of the prescriber's clients (redated by respondent)
> E. What makes you believe, if you do believe, that taking all those drugs together is safe, if you believe that?
> Lou
>The best and most qualified psychopharmacologist(s) in my part of the UK prescribes all of my meds and who I trust 100%. I've been on more potent combos than this so experience is a good indication of whats safe for myself. Do your research and you will find many 'so-called' dangerous combinations completely safe, or at least safe if treated carefully. Amphetamines with MAOIs is an example.
You seem to be having a go at me rather than being helpfull. Still, each to thier own opinion.
Posted by Lou Pilder on August 20, 2012, at 16:35:30
In reply to Re: Lou's warning-aflac » Lou Pilder, posted by Exister on August 20, 2012, at 11:14:18
> > > > Hi Exister, and welcome to Psycho-Babble.
> > > >
> > > > So, it sounds like your plan is to take Nardil, clonazepam, and bupropion, with Seroquel. Is this correct? What is it that you're treating?
> > > >
> > > > No matter what condition you're receiving treatment for, I wish you luck with your switch from Marplan to Nardil. May you receive relief from what you're suffering from.
> > > >
> > > > Tomatheus
> > >
> > > yes thats right, Seroquel (increase from 25-100mg), Marplan (120mg), Klonopin (4mg), Wellbutrin (300mg).
> > >
> > > Social phobia & major depression are my ills.
> > >
> > > Thanx for the comment
> > > Ex
> >
> > Ex,
> > You wrote the above.
> > The drugs that you are taking could kill you. You see, there are 3 of the 4 that are central nervous system depressants and respiratory depressants. When combined, they could have a geometric effect of suppression and death could happen. Not only that, but taking the drugs together can induce seizures. And on top of that, the drugs can induce a state where you could be compelled to kill yourself and/or others and if you stop the drugs, you could go into a state where people kill themselves and/or others.
> > Now I have some questions thht if you post anserws to them here, I could have the opportunity to post a response to you.
> > A. What kind of prescriber, if there is one, gives you all of these drugs to take together?
> > B. If one prescriber does not prescribe all of these drugs to you to take together, where do you obtain the drugs?
> > C. Have you looked up the prescriber's name in a registry of doctors that have been (redacted by respondent)
> > D. Have you found out if any of the prescriber's clients (redated by respondent)
> > E. What makes you believe, if you do believe, that taking all those drugs together is safe, if you believe that?
> > Lou
> >
>
> The best and most qualified psychopharmacologist(s) in my part of the UK prescribes all of my meds and who I trust 100%. I've been on more potent combos than this so experience is a good indication of whats safe for myself. Do your research and you will find many 'so-called' dangerous combinations completely safe, or at least safe if treated carefully. Amphetamines with MAOIs is an example.
> You seem to be having a go at me rather than being helpfull. Still, each to thier own opinion.Exister,
You wrote the above. If you could post answers to the following here, I could respond to you.
A. You state that psychopharmacologists(s) are the prescriber(s) of the drugs that you are taking. Is one giving you all of those drugs that you list?
B. If not, if more than one prescribed those drugs to you, does the one know that the other(s) prescribed the other drugs to you?
C. If not, then could there be an error that could kill you by the one prescriber not knowing what the other prescriber has you taking?
D. If there is no error and all know of all the drugs you are taking, could you ask the prescriber(s) if they know that those drugs combined could induce a depressed CNS and respiration that could cause your death?
E. Are you aware that there is an addiction potential in the taking of the benzodiazepine?
F. Are you aware that if one takes a BZD for life that long-term consequences could happen?
G. Could you ask your prescriber(s) if they take money from the drug manufacturers?
H. Are you aware that there is a difference between {support} and {reinforcement}?
K. Would you agree that what could be safe for you could be deadly to another?
L. Would you agree that just because you are alive now that that does not mean that you could not die suddenly tomrrow?
M. Could you post a citation here that states that the combination of drugs that your psychopharmacologist(s) gave you are "safe"?
N. Are you aware that it is generally agreed that about 42,000 peopoe died last year from psychotropic drugs from one way or another, and that the records show that many of those deaths were from taking combinations of psychiatric drugs?. Are you aware that the combining of psychotropic drugs could cause neuroleptic malignant syndrome which could lead to death?
P. Are you aware that my posting here is to warn others as well, that the combination of the drugs that you take could cause death because there was not another poster posting that warning?
Q. Are you aware that a lot of these drugs used here are not new drugs but a new name for an off-shoot of an old drug?
R. Would you agree that just because you are alive while taking these drugs that there could be a set of people here that are {less-confident) in what to do so they could go out and get the drugs that you take by some other means than having them prescribed to them, and then die from the drugs because since they are {less-confident}, they could think that what you take, they could take, and it would help them?
S. Are you aware that I know the chemical structure of these drugs and what they can do as a {nerve-agent} and how these drugs were devised and for what and by who and how the chemical constituamts were used in (redacted by respondent)?
Lou
Posted by Exister on August 25, 2012, at 13:21:17
In reply to Lou's reply-lezkonphydndt » Exister, posted by Lou Pilder on August 20, 2012, at 16:35:30
Just wondering the different times of how how long Seroquel (quetiepine) took to work for different people. Also if u could include other meds, esp if they had a direct influence on this time period, and dosages etc.
Please note that Only Unipolar depression sufferers are relevant to my situation and question.Im climbing dosage slowly and despite having a few mild suicidle thoughts during the 10 days on 50mg, since hitting 100mg 3 days ago no such thoughts have occured.
Posted by Exister on September 4, 2012, at 11:01:47
In reply to Seroquel question, posted by Exister on August 25, 2012, at 13:21:17
So after I had 10 days on 50mg then 10 days on 100mg Seroquel, I decided 50mg was most effective. In fact I was surprised at its power! I was in a dark place and it took me out of there, only slightly but relief nonetheless.
Just seen my doc yesterday and was decided to stay on 50mg as I was experiencing too much hypersomnia. He also added amitriptyline, starting very low 10mg to work slowly up to 100mg if needed. One pill last night and i feel it working! Nice :)
Posted by SLS on September 4, 2012, at 12:36:27
In reply to feel better!, posted by Exister on September 4, 2012, at 11:01:47
> So after I had 10 days on 50mg then 10 days on 100mg Seroquel, I decided 50mg was most effective. In fact I was surprised at its power! I was in a dark place and it took me out of there, only slightly but relief nonetheless.
> Just seen my doc yesterday and was decided to stay on 50mg as I was experiencing too much hypersomnia. He also added amitriptyline, starting very low 10mg to work slowly up to 100mg if needed. One pill last night and i feel it working! Nice :)
That's great!Thanks for the update.
Do you feel that you have more energy with the Seroquel?
Why was amitriptyline chosen?
- Scott
Posted by Exister on September 4, 2012, at 12:59:05
In reply to Re: feel better! » Exister, posted by SLS on September 4, 2012, at 12:36:27
Thanx Scott!
You know scott I DO have more energy whith Seroquel! It feels like it has re-activated the bupropion. Or perhapse its a synergistic effect. Whatever reason, it very much needed!The Amitriptyline was added as a replacement for the trimipramine I was taking some months ago, but stopped coz of sleep paralysis/ hypnopompic state as a side effect. So, the Amitriptyline is actually meant to become my main mood brightener replacement lol I cannot expect bupropion to take that role. Its always been an energy med for me (my hypersomnia) and little else.
Ex
Posted by Tomatheus on September 4, 2012, at 13:41:48
In reply to feel better!, posted by Exister on September 4, 2012, at 11:01:47
Exister,
I'm pleased to hear that you're feeling better. I hope that you continue to benefit from your medication combo.
Tomatheus
Posted by Exister on September 4, 2012, at 13:46:54
In reply to Re: feel better! » Exister, posted by Tomatheus on September 4, 2012, at 13:41:48
Posted by SLS on September 4, 2012, at 13:55:23
In reply to Re: feel better! » SLS, posted by Exister on September 4, 2012, at 12:59:05
> Thanx Scott!
> You know scott I DO have more energy whith Seroquel! It feels like it has re-activated the bupropion. Or perhapse its a synergistic effect. Whatever reason, it very much needed!
>
> The Amitriptyline was added as a replacement for the trimipramine I was taking some months ago, but stopped coz of sleep paralysis/ hypnopompic state as a side effect. So, the Amitriptyline is actually meant to become my main mood brightener replacement lol I cannot expect bupropion to take that role. Its always been an energy med for me (my hypersomnia) and little else.
> ExInterestingly, I have a friend who has described the role that Wellbutrin plays in her treatment in exactly the same way. She says that Wellbutrin gives her the energy to do stuff, but Pistiq gives her the motivation and reward to do stuff.
That's an interesting combination of drugs you are taking.
Good luck with the amitriptyline. If for some reason you find it too sedating or anticholinergic, you could try using nortriptylne instead.
- Scott
This is the end of the thread.
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