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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Prozac Pro on September 16, 2011, at 10:59:24
Hi All-
I just saw this promising abstract of a clinical trial of adjunctive SAMe for SSRI/SNRI sexual dysfunction.
http://www.ncbi.nlm.nih.gov/pubmed/21398094
Any experiences with this, specifically in conjunction with fluoxetine?
Dosages? The abstract is silent regarding the dosages used in t he trial.
Thanks for your sharing any thoughts.
Posted by mbluett on September 24, 2011, at 21:57:40
In reply to SAMe for SSRI (fluoxetine) sexual dysfunction?, posted by Prozac Pro on September 16, 2011, at 10:59:24
Hi there. I have tried SAMe in conjunction with Lexapro and also with Effexor. I found it very effective in increasing libido.
Posted by Chtorr281 on September 27, 2011, at 4:33:41
In reply to Re: SAMe for SSRI (fluoxetine) sexual dysfunction? » Prozac Pro, posted by mbluett on September 24, 2011, at 21:57:40
Can SAMe help with actual physical dysfunctional problems or just libido?
Posted by mbluett on September 27, 2011, at 6:51:34
In reply to Re: SAMe for SSRI (fluoxetine) sexual dysfunction?, posted by Chtorr281 on September 27, 2011, at 4:33:41
> Can SAMe help with actual physical dysfunctional problems or just libido?
Yes, it did help with both. It also potentiates the effect of the antidepressant, so it might be worth lowering your AD (with your pdoc) if you get too sedated or stimulated.
Posted by Prozac Pro on September 29, 2011, at 8:43:26
In reply to Re: SAMe for SSRI (fluoxetine) sexual dysfunction? » Chtorr281, posted by mbluett on September 27, 2011, at 6:51:34
> > Can SAMe help with actual physical dysfunctional problems or just libido?
>
> Yes, it did help with both. It also potentiates the effect of the antidepressant, so it might be worth lowering your AD (with your pdoc) if you get too sedated or stimulated.Thanks- what is the dose you use? How much time before a response is experienced?
Posted by mbluett on September 29, 2011, at 12:38:41
In reply to Re: SAMe for SSRI (fluoxetine) sexual dysfunction?, posted by Prozac Pro on September 29, 2011, at 8:43:26
Hi there. It took it for 3 or 4 days @ 200mg daily before I noticed the effect on libido. I tried 400mg daily but it made me manic and agitated.
Posted by Prozac Pro on September 29, 2011, at 13:35:57
In reply to Re: SAMe for SSRI (fluoxetine) sexual dysfunction? » Prozac Pro, posted by mbluett on September 29, 2011, at 12:38:41
> Hi there. It took it for 3 or 4 days @ 200mg daily before I noticed the effect on libido. I tried 400mg daily but it made me manic and agitated.
Interesting. The study I cited above started with a dose of 800 mg per day, increasing to 1,600. That's a lot SAME, and expensive, too. It's encouraging that you found a lower dose to be effective.
This is the end of the thread.
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