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Dr. Bob is Robert Hsiung, MD,
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Posted by linkadge on April 1, 2011, at 16:29:16
Linkadge
Posted by BrainDamage on April 2, 2011, at 12:40:16
In reply to quetieptine shrinks the hippocampus and striatum, posted by linkadge on April 1, 2011, at 16:29:16
That is bad news
I like Quetiapine, but I'm not entirely supprised since Olanzapine also causes brain atrophy.
I feel that Quetiapine is a good drug, I wonder if it has this effect even at low doses?
Posted by Brot on April 2, 2011, at 13:20:05
In reply to quetieptine shrinks the hippocampus and striatum, posted by linkadge on April 1, 2011, at 16:29:16
I think that ap's shrink the brain is the false conclusion.
Schizophrenia shrinks the brain.
And they compared first episode schizophrenics on quetiapine with healthy controls...
As far as I know, Antipsychotics decrease the brain shrinkage in shizophrenia. I once read a study comparing first episode schizoprenics on Haldol versus unmedicated schizophrencis. The unmedicated ones hat twice the shrinkage than medicated ones had...
Posted by jono_in_adelaide on April 11, 2011, at 22:46:35
In reply to Re: quetieptine shrinks the hippocampus and striatum, posted by Brot on April 2, 2011, at 13:20:05
Low doses of quietipine are just a strong antihistamine - doxepin or Phenerganwould do the same thing, and be safer
Posted by SLS on April 12, 2011, at 5:55:45
In reply to Re: quetieptine shrinks the hippocampus and striatum, posted by jono_in_adelaide on April 11, 2011, at 22:46:35
> Low doses of quietipine are just a strong antihistamine - doxepin or Phenerganwould do the same thing, and be safer
I have seen 50mg of quetiapine produce a robust antidepressant effect when added to ongoing risperidone treatment. Of course, I don't know why. Perhaps NE reuptake inhibition at low dosages is greater in magnitude than is generally thought. I believe it is the metabolite that is more active.
- Scott
This is the end of the thread.
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