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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by bulldog2 on March 12, 2010, at 17:43:13
I find that parnate is very effective in getting one out of a deep depression. However for me it leaves me a bit flat. One of my symptoms is I'm reclusive. Now even when parnate lifts me out of my depression I am still not sociable. When neurontin works it makes me very sociable. However when I mix neurontin with parnate neither drug works as well as by itself.
I have found a good mix. Oxycodone with parnate. They are very synergistic. I feel the dopamine lift from parnate enhances the oxycodone. Very nice feeling.
More p-docs should use parnate with the appropriate opiate as they do blend very well.
Again parnate by itself is very flat for me. Really needs other meds to get a really good mood.However is effective to get one out of the pits.
Posted by Phillipa on March 12, 2010, at 19:38:54
In reply to Parnate Needs to Be Spiced Up, posted by bulldog2 on March 12, 2010, at 17:43:13
My pdoc thought tramadol would be good for me and recognizes from what her patients tell her that some are opiod responders. But the medical system is keeping close tabs on pain meds and she won't prescribe as Dea license could be lost. Suggested a pain clinic but said they also are limited and prefer physical theraphy. Phillipa
Posted by JayBTV2 on March 13, 2010, at 7:36:02
In reply to Re: Parnate Needs to Be Spiced Up » bulldog2, posted by Phillipa on March 12, 2010, at 19:38:54
> My pdoc thought tramadol would be good for me and recognizes from what her patients tell her that some are opiod responders. But the medical system is keeping close tabs on pain meds and she won't prescribe as Dea license could be lost. Suggested a pain clinic but said they also are limited and prefer physical theraphy. Phillipa
You can't use Tramadol w/ Parnate since it also blocks the reuptake of Serotonin. But if on it's own some find it helpful. I'd be scared of tolerance/addiction.
As for Parnate I'm about 4 months into my trial. Finally did 3 weeks on 60mg and now I'm up to 70mg for the last few days. It's more subtle than I was expecting but it's definitely helping. For me personally I notice it most in the self-confidence department when I'm forced to be amongst people.
Also lately I've been taking 30mg in the morning, 30mg at noon, and 10 around 3ish. That second dose has been giving me a nice "chest buzz" for some reason the last week or so. I recently added Fish oil and Magnesium (good kind - not oxide) to my regime so perhaps that's what's giving me more of the immediate effect. I read one post from the archives where someone taking fish oil and Parnate talked about chest adrenalin - perhaps that's what I'm experiencing. Either way for me it's a nice feeling.
As for oxycodone I had a minor (luckily) problem with that a few months back. I was taking it occasionally to feel good - not for pain. That was before and during my tapering up of Parnate. It definitely lasted longer with Parnate. However for me personally that's something I quit and don't plan to go back to. Way too risky for me as far as addiction is concerned. I've seen what people go through when you start to _need_ it. Last thing I want is to be pawning my guitars to get a 30mg pill because I feel like crap :)
My current meds:
Parnate 70mg
Lamictal 200mg
Lithium 600mg
Seroqual (~100mg sleep)
Fish oil
Magnesium (800mg Glycinate/Taurate/etc)-Jay
Posted by Maxime on March 18, 2010, at 15:54:04
In reply to Parnate Needs to Be Spiced Up, posted by bulldog2 on March 12, 2010, at 17:43:13
I imagine that it would be hard to get an opiate prescribe to you ( not just you, anyone). I don't think my pdoc would give me one.
Posted by sukarno on March 18, 2010, at 21:52:11
In reply to Re: Parnate Needs to Be Spiced Up » bulldog2, posted by Maxime on March 18, 2010, at 15:54:04
Well, as tramadol is not scheduled in most US states (in other words it is not a controlled substance except in a few states), I would think it wouldn't be too much of a problem. It could be that the physician is afraid the patient might want the "real thing" (hydrocodone, oxycodone, etc) if they are on tramadol for the long term. I don't know though. I think they might be afraid of chastisement from their state medical board.
In the United States, a drug can be used off-label for almost any purpose though.
That said, there are anecdotes coming in about how distressing the withdrawal syndrome is from tramadol. It has a withdrawal syndrome similar to venlafaxine (Effexor), with the added misery of opioid withdrawal tacked on.
Probably, since it has mild opioid properties (comparing apples to oranges here.. it could be like codeine I suppose) it shouldn't be as distressing as discontinuing hydrocodone or oxycodone.
This is the end of the thread.
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