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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by bulldog2 on October 18, 2009, at 18:23:34
I wonder has anyone ever read that parnate has a sweetspot such as nortriptyline has? Does it work best at a certain blood level?
It seems as if everyone titrates rapidly upwards to achieve remission. Perhaps people are missing a certain blood level that would be optimum.
Posted by delna on October 19, 2009, at 10:02:14
In reply to Is There A Parnate Sweetspot?, posted by bulldog2 on October 18, 2009, at 18:23:34
Hmmm.....
you know I read somewhere that it should be dosed by weight.
Maybe it was in the psychobabble tips section. Not sure.
Posted by Sunbath on October 19, 2009, at 17:29:52
In reply to Re: Is There A Parnate Sweetspot? » bulldog2, posted by delna on October 19, 2009, at 10:02:14
Hi Delna,
wasn't that for Nardil?
BTW: Thanks for your mail! Sorry that I didn't answer it yet, I just came home, it's 00:30am and I had some drinks. Not able to do that now :/
Will answer tomorrow :)
I hope you had a day without too much hypotension and sedation!!Have a good night!
Posted by delna on October 19, 2009, at 22:44:40
In reply to Re: Is There A Parnate Sweetspot? » delna, posted by Sunbath on October 19, 2009, at 17:29:52
Yes, you are right- that is for nardil
But according to the psychobabble tips, there is a way to test how much Parnate you need...but I wonder if labs perform these testsDate: Sat, 1 Apr 1995 13:33:03 -0800 (PST)
From: Ivan Goldberg <psydoc@psycom.net>
Subject: Non-response to tranylcypromineThe commonest reason people do not respond to tranylcypromine (Parnate) is an inadequate dose. When using an MAOI I follow platelet MAO levels and keep increasing the dose is sufficient to reduce those levels almost to zero. This often takes > 60 mg/day of tranylcypromine.
Sunbath,
About answering my mail- please, please don't feel pressured. I know you have school (and a life :) ) so reply whenever you feel like. I take no offense at all.
Just hope you are doing well. TC
D
Posted by bulldog2 on October 20, 2009, at 13:16:51
In reply to Re: Is There A Parnate Sweetspot? » Sunbath, posted by delna on October 19, 2009, at 22:44:40
> Yes, you are right- that is for nardil
> But according to the psychobabble tips, there is a way to test how much Parnate you need...but I wonder if labs perform these tests
>
> Date: Sat, 1 Apr 1995 13:33:03 -0800 (PST)
> From: Ivan Goldberg <psydoc@psycom.net>
> Subject: Non-response to tranylcypromine
>
> The commonest reason people do not respond to tranylcypromine (Parnate) is an inadequate dose. When using an MAOI I follow platelet MAO levels and keep increasing the dose is sufficient to reduce those levels almost to zero. This often takes > 60 mg/day of tranylcypromine.
>
>
> Sunbath,
> About answering my mail- please, please don't feel pressured. I know you have school (and a life :) ) so reply whenever you feel like. I take no offense at all.
> Just hope you are doing well. TC
> D
>
>It seems from your answers there really is not a sweet spot as there is in nortriptyline. Just need a high enough dose to reduce mao levels to almost zero. However might need a blood test to determine that. Thanks for your answers.
Posted by ace on October 21, 2009, at 19:50:17
In reply to Is There A Parnate Sweetspot?, posted by bulldog2 on October 18, 2009, at 18:23:34
Perhaps people are missing a certain blood level that would be optimum.
This is very common with the MAOI's!!!
I remember a doctor, D Burns, used to reccomend like 10mg Parnate for a therapeutic dose.....way too low in my experience!!!!!
Posted by FredPotter on October 26, 2009, at 15:58:31
In reply to Re: Is There A Parnate Sweetspot?, posted by bulldog2 on October 20, 2009, at 13:16:51
I was told that the working dose gives hypotension on standing and further hypotension when measured standing immediately after the first test
This is the end of the thread.
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