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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by number42 on October 12, 2009, at 13:01:01
I'm on high dose prozac 80 mgs. and just added 150 mgs of trazodone for insomnia. Am i in danger of serotonin syndrome?
#42
Posted by Phillipa on October 12, 2009, at 13:58:46
In reply to trazodone combined with prozac-dangerous?, posted by number42 on October 12, 2009, at 13:01:01
Did you doc put you on it if so shouldn't it be okay? Love Phillipa
Posted by X-ray on October 12, 2009, at 14:42:57
In reply to trazodone combined with prozac-dangerous?, posted by number42 on October 12, 2009, at 13:01:01
Hi,
The concentration of trazodone and its active metabolite increases by adding fluoxetine.
This could lead to increased sedation and serotonin related side effects.
This combination should be avoided.
Best regards,
X-ray
Posted by zzzz7 on October 12, 2009, at 15:41:59
In reply to Re: trazodone combined with prozac-dangerous?, posted by X-ray on October 12, 2009, at 14:42:57
You might start at 25mg and see how little you need to sleep.
Posted by Sunbath on October 12, 2009, at 17:06:11
In reply to Re: trazodone combined with prozac-dangerous?, posted by zzzz7 on October 12, 2009, at 15:41:59
Hey!
Trazodone is a very VERY weak serotonine reuptake blocking agent!I really don't think it could be dangerous, but to begin with 150mg sounds a bit high.. you should be very sedated at that dose when you aren't accustomes to trazodone at all.. but I really don't think that you would be in danger of serotonine syndrome.. but I'm no doctor and no expert at all!
Take care! Good luck to you!
Posted by emmanuel98 on October 12, 2009, at 20:09:17
In reply to trazodone combined with prozac-dangerous?, posted by number42 on October 12, 2009, at 13:01:01
My p-doc, who is very cautious about combining meds, gave me as much trazadone as I wanted -- up to 200mg worked for me for insomnia -- while I was taking 30mg of lexapro. So I don't think serotonin syndrome is a worry. It is a worry with MAOIs however.
Posted by Deneb on October 12, 2009, at 23:32:34
In reply to trazodone combined with prozac-dangerous?, posted by number42 on October 12, 2009, at 13:01:01
Not sure, but I've been on trazodone, prozac AND celexa (and risperdal) all at once and I was OK. Everyone is different though.
This is the end of the thread.
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