Psycho-Babble Medication Thread 912966

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Re: SSRI users - what is the most prosocial SSRI?

Posted by SLS on August 19, 2009, at 18:17:48

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by bleauberry on August 19, 2009, at 18:03:55

> If you are talking about being comfortable in a crowd, not nervous, then I would say Paxil.
>
> If you are talking about desiring to introduce yourself to strangers at a gathering and mingling around the room, none. You'll be too numb to care.

I found Effexor to be of help, and I never felt numb nor apathetic while taking it. I don't recall being numb on any of the SSRI/SNRI drugs with the possible exception of Zoloft. I don't think that numbness is guaranteed to occur with these drugs.


- Scott

 

Re: SSRI users - what is the most prosocial SSRI? bleauberry

Posted by Maxime on August 19, 2009, at 18:19:05

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by bleauberry on August 19, 2009, at 18:03:55

> If you are talking about being comfortable in a crowd, not nervous, then I would say Paxil.
>
> If you are talking about desiring to introduce yourself to strangers at a gathering and mingling around the room, none. You'll be too numb to care.

Very well put!

I've read that clonazepam can help people with social avoidance problems (as in wanting to introduce yourself to strangers at a gathering).

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by sowhysosad on August 19, 2009, at 19:44:50

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by SLS on August 19, 2009, at 18:17:48

>I don't think that numbness is guaranteed to occur with these drugs.
>
>
> - Scott

Nope, no numbness here either on 3 of them.

I think that's a generalisation.

 

Re: SSRI users - what is the most prosocial SSRI? sowhysosad

Posted by Phillipa on August 19, 2009, at 21:01:29

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by sowhysosad on August 19, 2009, at 19:44:50

I agree as many people I know are on them and doing very well. Phillipa

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by sam K on August 20, 2009, at 2:19:17

In reply to Re: SSRI users - what is the most prosocial SSRI? Michael Bell, posted by Maxime on August 19, 2009, at 11:51:46

the only anti depressant I could stand was adderall. And that only lasted for a few monthes till I went crazy lol. its so funny because ALL ALL antidepressants are horrible for me. I never made any progress ever! I am a bipolar/something or other. SSRIs just make me sit in my basesment and play computer games all day.
GOD I AM GLAD THE MEDICINE TRAIN has ended. Ive tried every med and am glad! Sure they work for some symptoms, but cause so many freaking side effects. Weight gain, anxiety, lazienss,
Adderall was pretty prosocial, but if you have ANY bipolar you will flip out bat sh*t crazy and read whole books in a day and your HEAD WILL EXPLODE!!!

 

Re: SSRI users - what is the most prosocial SSRI? sam K

Posted by morganator on August 20, 2009, at 3:16:28

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by sam K on August 20, 2009, at 2:19:17

I'm guessing you are not on any medication at the moment???

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Alexanderfromdenmark on August 20, 2009, at 3:55:05

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by SLS on August 19, 2009, at 12:55:10

> Am I missing something, or is there no group of drug-free depressed patients?
>
>
> - Scott
>
>
> > > Uuuh that's scary why would that be so?
> >
> > Cause SSRI's sink them into the ground. Not good for male depression or overall health.
> >
> > PURPOSE: To evaluate endocrine profile and hypothalamic-pituitary-testis (HPT) axis in male depressed patients with selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction (SDF). MATERIALS AND METHODS: Eighty-six fertile depressed male patients with SSRI-induced SDF, aged 18 to 50 years, were enrolled in the study (group 1). Sixty-two age-matched depressed fertile patients who currently receive one of the SSRIs but without SDF (group 2), and 68 age-matched healthy fertile men who had never received a psychiatric diagnosis (group 3) served as controls. Pretreatment evaluation included history and physical examination and International Index of Erectile Function. Two blood samples were drawn from each subject at 20-minute intervals for the determination of the resting levels of the following hormones: luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, prolactin, and estradiol. The HPT axis was also assessed using the gonadotropin-releasing hormone test. RESULTS: The prevalence of hormonal abnormalities in groups 1, 2, and 3 were 83.7% (72), 51.6% (32), and 11.8% (7), respectively (P = 0.001 vs group 1 and 0.007 vs group 2). Compared with normal controls, the subjects taking SSRIs had significantly lower serum levels of LH, FSH, and testosterone. In addition, there were significantly decreased LH and FSH responses to gonadotropin-releasing hormone test in groups 1 and 2 compared with normal controls. Of patients in groups 1 and 2, 68 (79.1%) and 27 (43.5%) had elevated serum levels of prolactin (P = 0.0001 vs group 1 and 0.001 vs group 2). CONCLUSIONS: Most depressed subjects taking SSRIs with and without SDF had diminished HPT axis function. This should be replicated in further studies.
> >
> >
> >
>
>
Sls you are right. There should have been a control group of depressed patients not taking drugs, but still if you read the whole study, I don't really feel there needs to be.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by SLS on August 20, 2009, at 6:44:40

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 3:55:05

> Sls you are right. There should have been a control group of depressed patients not taking drugs, but still if you read the whole study, I don't really feel there needs to be.

I find abstracts difficult to follow sometimes.


- Scott

 

Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark

Posted by Garnet71 on August 20, 2009, at 7:11:07

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 3:55:05

Alexander, I was interested in this study too. I don't normally pay much attention to the methodology of these medication studies since I am not a scientist (and also don't have time to read them thoroughly), but I did notice there was a control group. Maybe you could give us a link or citation, those interested could read more about this?

I've come across studies in the past where medications helped regulate the HPA for those with PTSD. Studies have shown people with childhood trauma have irregular HPA regulation to begin with, so I've read. Not that you've personally had childhood trauma-I think I remember your saying that you did not--but I just wanted to point that out.

Also, I take some health-related courses and in doing some (unrelated) research, I came across an article that men in Denmark (if your screename reflects your country of origin!) have unusually low testostorone levels in comparison with those in other states. I'm not kidding-you should google that.

Alexander, your situation really sucks. I'd be pssed off if drugs were the cause of the destruction of my sex life--for sure. I mean let's face it, sex is a big part of the human experience. I can't really imagine what it would be like, but it seems it would be like having a part of your autonomy denied. Autonomy is probably not the right word. I can't even find the word.

You are so young and it just sucks. I don't post here very much anymore, but I do read your posts from time to time, wondering if you've gotten better. Hang in there :)

RE: the control group:

...and 68 age-matched healthy fertile men who had never received a psychiatric diagnosis (group 3) served as controls.

...Compared with normal controls, the subjects taking SSRIs had significantly lower serum levels of LH, FSH, and testosterone. In addition, there were significantly decreased LH and FSH responses to gonadotropin-releasing hormone test in groups 1 and 2 compared with normal controls.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Garnet71 on August 20, 2009, at 7:27:16

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 3:55:05

grr..googling brings up so much about this...I wish I remember where I found that article...this issue seems to be a world trend, but for some reason, Denmark has different circumstances. Okay, maybe this note will leave you at a starting point if you are interested.

"In Denmark, 40 per cent of young men have a "subnormal" sperm count and the rate of testicular cancer is among the highest in the world."

http://au.lifestyle.yahoo.com/b/mens-health/4033/testosterone-underattack/

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Alexanderfromdenmark on August 20, 2009, at 8:14:57

In reply to Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark, posted by Garnet71 on August 20, 2009, at 7:11:07

> Alexander, I was interested in this study too. I don't normally pay much attention to the methodology of these medication studies since I am not a scientist (and also don't have time to read them thoroughly), but I did notice there was a control group. Maybe you could give us a link or citation, those interested could read more about this?
>
> I've come across studies in the past where medications helped regulate the HPA for those with PTSD. Studies have shown people with childhood trauma have irregular HPA regulation to begin with, so I've read. Not that you've personally had childhood trauma-I think I remember your saying that you did not--but I just wanted to point that out.
>
> Also, I take some health-related courses and in doing some (unrelated) research, I came across an article that men in Denmark (if your screename reflects your country of origin!) have unusually low testostorone levels in comparison with those in other states. I'm not kidding-you should google that.
>
> Alexander, your situation really sucks. I'd be pssed off if drugs were the cause of the destruction of my sex life--for sure. I mean let's face it, sex is a big part of the human experience. I can't really imagine what it would be like, but it seems it would be like having a part of your autonomy denied. Autonomy is probably not the right word. I can't even find the word.
>
> You are so young and it just sucks. I don't post here very much anymore, but I do read your posts from time to time, wondering if you've gotten better. Hang in there :)
>
> RE: the control group:
>
> ...and 68 age-matched healthy fertile men who had never received a psychiatric diagnosis (group 3) served as controls.
>
> ...Compared with normal controls, the subjects taking SSRIs had significantly lower serum levels of LH, FSH, and testosterone. In addition, there were significantly decreased LH and FSH responses to gonadotropin-releasing hormone test in groups 1 and 2 compared with normal controls.

High Garnet. It's not just the sexual dysfunction that annoys the hell out me(though that really sucks) it's all the other things that come with low testosterone. increased belly fat, weakness, exercise intolerance, muscle loss, cognitive dysfunction. And my skin has lost some of it's elasticity. I'm just like come on, I'm 22! I feel like I turned 90 in 2 years. I was desperate enough already, I can't handle all this, and I'm getting zero help from the doctors.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Alexanderfromdenmark on August 20, 2009, at 8:51:05

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by SLS on August 20, 2009, at 6:44:40

> > Sls you are right. There should have been a control group of depressed patients not taking drugs, but still if you read the whole study, I don't really feel there needs to be.
>
> I find abstracts difficult to follow sometimes.
>
>
> - Scott


Unfortunately I can't find a link to the whole study. I've got it here on my computer, but havn't got a server to put up on. The thing that sepereates SSRI patients from the controls if is significantly elevated levels of prolactin, significantly decreased LH, FSH and testosterone and decreased or no response to meds that stimulate LH and FSH secretion.

Basicly they are secondary hypogonadal while on the drug. The elevated prolactin also suggests a significan't decraese in dopamine. Supporting our dopamine depletion theories.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Garnet71 on August 20, 2009, at 9:51:20

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 8:14:57

((((Alexander))))

Hey is there anyway you can contact a Uni in your area and get involved in a study? that way, Drs. would really look into your issues and lots of tests, etc.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Alexanderfromdenmark on August 20, 2009, at 10:16:09

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Garnet71 on August 20, 2009, at 9:51:20

> ((((Alexander))))
>
> Hey is there anyway you can contact a Uni in your area and get involved in a study? that way, Drs. would really look into your issues and lots of tests, etc.


I already was. But i've dropped out now, because I can't cut it. I havn't read a uni all time I was there and i'm so tired I'm nearly bed-ridden. I've gone down to a clinic in belgium that diagnosed me hypothyroid, hypogonadal and in adrenal fatigue. The whole thing is costing me a fortune i don't have and it's awfully inconveniet that they are located in another country.

I'm crossing fingers though that they will help me. I don't want to take supplemental testosterone, because I don't want to take it the rest of my life and it's only a recent issue. I'd rather try to restart my HPG axis.

It's a nightmare though, being like this and not getting any help from my local doctors. I have to figure out everything on my own and pay for everything when I'm completely broke.

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by linkadge on August 20, 2009, at 20:15:18

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by sam K on August 20, 2009, at 2:19:17

>SSRIs just make me sit in my basesment and play >computer games all day.

So true, so true - and (if I may add) not care about the consequences.

Linkadge

 

Re: SSRI users - what is the most prosocial SSRI? linkadge

Posted by morganator on August 20, 2009, at 21:06:06

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by linkadge on August 20, 2009, at 20:15:18

I would like to know what antidepressant does not make you not care about the consequences of things as much- MAOIs?? SNRIs?? Tricyclics??

 

Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark

Posted by Sigismund on August 21, 2009, at 2:42:34

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 10:16:09

>I don't want to take supplemental testosterone, because I don't want to take it the rest of my life and it's only a recent issue. I'd rather try to restart my HPG axis.

Probably good thinking.

 

Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark

Posted by SLS on August 21, 2009, at 6:18:49

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 20, 2009, at 10:16:09

> I don't want to take supplemental testosterone, because I don't want to take it the rest of my life and it's only a recent issue. I'd rather try to restart my HPG axis.

How would you go about that?

A brief application of HCG?


- Scott

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by Alexanderfromdenmark on August 21, 2009, at 7:37:29

In reply to Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark, posted by SLS on August 21, 2009, at 6:18:49

> > I don't want to take supplemental testosterone, because I don't want to take it the rest of my life and it's only a recent issue. I'd rather try to restart my HPG axis.
>
> How would you go about that?
>
> A brief application of HCG?
>
>
> - Scott
>

Clomid, Nolvadex, Lowering E2(if too high), dopamine agonists or similar drugs. i've never done it before so I dunno. Clomid seems to be the gold standard for trying restart. Question is, will doctors play ball?

 

Re: SSRI users - what is the most prosocial SSRI?

Posted by linkadge on August 21, 2009, at 18:19:08

In reply to Re: SSRI users - what is the most prosocial SSRI? linkadge, posted by morganator on August 20, 2009, at 21:06:06

>I would like to know what antidepressant does >not make you not care about the consequences of >things as much- MAOIs?? SNRIs?? Tricyclics??

Probably high dose paxil plus zyprexa. You won't care if you lay around all day and your legs atrophy and go gangrenous and the stench is so bad that your neighbours call the police.

Linkadge

 

Re: SSRI users - what is the most prosocial SSRI? linkadge

Posted by morganator on August 21, 2009, at 19:34:32

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by linkadge on August 21, 2009, at 18:19:08

I think you misunderstood my post. I was talking about medications that do not make you this way...

 

Re: SSRI users - what is the most prosocial SSRI? Alexanderfromdenmark

Posted by viper1431 on August 22, 2009, at 0:02:13

In reply to Re: SSRI users - what is the most prosocial SSRI?, posted by Alexanderfromdenmark on August 19, 2009, at 11:59:04

Wish i could take that bet :P
I was on an ssri (lexepro) when i asked for a testosterone test and the results showed them to be strangly high. And i don't work out and take any accociated things.

> Michael I'll wager a 10 bucks that if you are on a SSRI right now, you have low testosterone l

 

Re: SSRI users - what is the most prosocial SSRI? Michael Bell

Posted by viper1431 on August 22, 2009, at 0:03:53

In reply to SSRI users - what is the most prosocial SSRI?, posted by Michael Bell on August 19, 2009, at 11:14:27

For me lexepro, the other ssri's made me emotionally numb or flat and i didn't like it but when i gave lexepro a go last year i found i was suddenly able to just talk and reply to people rather than grunting. The only prob i had with it along with the other ssri's is they make my body feel weak during the day

> Just curious as to which SSRI had the greatest impact on prosociability. Any feedback would be great. I'm thinking about switching. Thanks!

 

THANKS FOR ALL THE REPLIES!!! (nm)

Posted by Michael Bell on August 24, 2009, at 22:16:01

In reply to SSRI users - what is the most prosocial SSRI?, posted by Michael Bell on August 19, 2009, at 11:14:27

 

Re: THANKS FOR ALL THE REPLIES!!! Michael Bell

Posted by floatingbridge on August 26, 2009, at 11:41:29

In reply to THANKS FOR ALL THE REPLIES!!! (nm), posted by Michael Bell on August 24, 2009, at 22:16:01

Hi Michael,

please keep us updated.

best,

fb


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