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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Zana on July 20, 2009, at 15:19:18
Does anyone have any theories about why Remeron would theoretically be such a potent augementor of Effexor? I am taking it with Pristiq, the new Effexor. I had no AD effect from the Remeron alone but did feel much better when Pristiq was added to the mix.
I'd like to decrease the Remeron. I'm on 45mgs. But I'm afraid of losing the AD effect of the combination, if in fact that's what's helping.
Thanks
Zana
Posted by SLS on July 20, 2009, at 16:05:10
In reply to California Rocket Fuel?, posted by Zana on July 20, 2009, at 15:19:18
> Does anyone have any theories about why Remeron would theoretically be such a potent augementor of Effexor? I am taking it with Pristiq, the new Effexor. I had no AD effect from the Remeron alone but did feel much better when Pristiq was added to the mix.
> I'd like to decrease the Remeron. I'm on 45mgs. But I'm afraid of losing the AD effect of the combination, if in fact that's what's helping.
> Thanks
> ZanaI'm really not sure what is behind the theory why the combination should work. Both drugs do different things, so perhaps they are complimentary. Pristiq inhibits the reuptake of both 5-HT and NE. Remeron might act synergistically to enhance NE neurotransmission through its ability to antagonize presynaptic NE alpha-2 autoreceptors. Remeron also facilitates dopamine activity downstream (fronto-cortical) by blocking 5-HT2c receptors.
If it is necessary, you can go higher with the Remeron. The label says you can go up to 45mg, but I have seen plenty of people go to 60mg and 75mg.
Good luck.
- Scott
Posted by Phillipa on July 20, 2009, at 16:16:07
In reply to Re: California Rocket Fuel? » Zana, posted by SLS on July 20, 2009, at 16:05:10
Zana so it is also helping with the pristiq interesting as two different types of effexor. Great to hear. Hope things continue to improve for you. Love Phillipa
Posted by rjlockhart04-08 on July 20, 2009, at 20:24:26
In reply to California Rocket Fuel?, posted by Zana on July 20, 2009, at 15:19:18
Well all I need is Rocket fuel to get Cali, Rocket fuel.....getting unstable....repeat, all systems are unstable, The Matinic hit a problem in 2005, and it's about to under now. Been sinkin since 2005....back at at ya!
Evacuation plans are being made, 2009, I do not want to be deep and and forgotten, mm mm, get that rocket fuel, stable or not, and get out, it's time for rj to hit big time in New York. Big time! Man I'm so big, last time I had a bigmac at McDonald's was.........? no money!
Man, this called getting tough! realizing the world wasnt what i thought it was, reality check!
rj
Posted by floatingbridge on July 20, 2009, at 21:33:18
In reply to California Rocket Fuel?, posted by Zana on July 20, 2009, at 15:19:18
Hi Zana,
Wondering if increasing the pristiq would alter the ratio of remeron/pristiq synergy? Maybe then, (just guessing), one could go up on remeron?
fb
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