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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by myco on February 5, 2009, at 18:41:43
Has anyone with anxiety taking a maoi had good results with augmenting with: L-tyrosine or DL-Phenylalanine? I'm not even sure if a combo like this is safe but I want to augment for AD effect (ie more energy, stimulation) but not to the point where i'm cringing with anxiety. What doses worked for you?
thnx,
Posted by Jim45 on February 7, 2009, at 15:50:17
In reply to MAOI use with: L-TYROSINE or DL-Phenylalanine?, posted by myco on February 5, 2009, at 18:41:43
With careful attention to dose and time, I've had fantastic results from Selegiline and PEA (phenylethylamine - not DL-Phenylalanine).
I had terrible amotivation, no energy, and depression. That's all gone now and I've been using that combo for almost 2 months.
I do take a small dose of Effexor - 37.5 mg - divided in 1/2 or 1/3 twice daily also.
I'm 200 pounds, and for me 1/3 or 1/4 tablet of Selegiline every 2-3 hours and 100 +/- mg of PEA hourly +/- (yeah, it wears off quickly and has to be taken annoying regularly) is a therapeutic regimen.
I take it from around 11 AM until 7 or 8 PM. Stopping sooner causes tiredness for a couple of hours.
I was suffering damage from high-dose Effexor I'd been on for 5 or 6 years. Been miserable for almost 2 years and decided something had to give. Life's too short.
I've been like the person I was years ago for the past couple of months and hope this regimen doesn't stop working.
Taking too much is dangerous and can be psychologically addictive. If you're using or gonna use meds to cope find something else.
One last thing - it took about a month after I noticed BP/fluid retention problems to get the dose and times right. Most folks quickly give up due to bad experiences because they took too much or it was too complex a regimen. It is a pain, but it's well worth it. Only opiates and high doses of Effexor have helped me in the past. This is the best thing I've EVER used to help me. It's incredible.
Good luck!!
Posted by myco on February 7, 2009, at 16:23:17
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine?, posted by Jim45 on February 7, 2009, at 15:50:17
Posted by myco on February 7, 2009, at 16:24:34
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine? (nm) » Jim45, posted by myco on February 7, 2009, at 16:23:17
Posted by Ant-Rock on February 9, 2009, at 18:55:47
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine?, posted by Jim45 on February 7, 2009, at 15:50:17
> With careful attention to dose and time, I've had fantastic results from Selegiline and PEA (phenylethylamine - not DL-Phenylalanine).
>
> I had terrible amotivation, no energy, and depression. That's all gone now and I've been using that combo for almost 2 months.
>
> I do take a small dose of Effexor - 37.5 mg - divided in 1/2 or 1/3 twice daily also.
>
> I'm 200 pounds, and for me 1/3 or 1/4 tablet of Selegiline every 2-3 hours and 100 +/- mg of PEA hourly +/- (yeah, it wears off quickly and has to be taken annoying regularly) is a therapeutic regimen.
>
> I take it from around 11 AM until 7 or 8 PM. Stopping sooner causes tiredness for a couple of hours.
>
> I was suffering damage from high-dose Effexor I'd been on for 5 or 6 years. Been miserable for almost 2 years and decided something had to give. Life's too short.
>
> I've been like the person I was years ago for the past couple of months and hope this regimen doesn't stop working.
>
> Taking too much is dangerous and can be psychologically addictive. If you're using or gonna use meds to cope find something else.
>
> One last thing - it took about a month after I noticed BP/fluid retention problems to get the dose and times right. Most folks quickly give up due to bad experiences because they took too much or it was too complex a regimen. It is a pain, but it's well worth it. Only opiates and high doses of Effexor have helped me in the past. This is the best thing I've EVER used to help me. It's incredible.
>
> Good luck!!This is really interesting.
Where would one go to obtain PEA?
Thanks,Anthony
Posted by Jim45 on February 9, 2009, at 22:19:11
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine? » Jim45, posted by Ant-Rock on February 9, 2009, at 18:55:47
Dear Antrock -
Just google "buy phenylethylamine"
PLEASE .....
Research combining PEA with Selegiline before using the combo.
It can be unpleasant and dangerous if you take too much of either.
For me, a 200 pound male, 1/4 or 1/3 (MAX) of a 5 mg Selegiline tablet every 2-3 hours, and 100+/- mg of PEA every hour or so (you'll know when) is a therapeutic dose.
It's incredible. As I recently commented on someone elses post, I have no desire to drink alcohol or smoke pot anymore. I have my old life back.
I start taking the combo around lunchtime. I even feel okay/good in the mornings. Once you start though you may find yourself needing it until an hour or so before bedtime. When it wears off you'll get very tired. If you're forgetful, write down when you take what. A couple of times I've forgotten and took an extra dose. It was unpleasant and scary. It's an annoying and complex regimen, but the outcome in my opinion (and for my neurological makeup and those with similar problems) it's well worth it.
JUST BE CAREFUL!!!
And - Good luck!
Jim
Posted by myco on February 13, 2009, at 10:55:10
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine?, posted by Jim45 on February 7, 2009, at 15:50:17
Hey, do you know anything about tyrosine competing for transport across the blood-brain barrier with tryptophan and recommendations to take 5-htp to deal with the lag on seratonin (derived from the tryptophan)? I've bought the tyrosine and will add a tiny little dose (100mg twice a day to start) but I wont last long on it if it depresses me by messing with seratonin.
Posted by Jim45 on February 13, 2009, at 14:45:59
In reply to Re: MAOI use with: L-TYROSINE or DL-Phenylalanine? » Jim45, posted by myco on February 13, 2009, at 10:55:10
Sorry Myco.
Only know about things I've dealt with and limited other meds/drugs stuff.
I have to add that like what I just wrote to X_ander, I now have concerns about combining PEA and Selegiline. Here's that post:
Dear X_ander.
I posted the following yesterday. Guess it didn't get through. Man I'm sorry, but I'm SO detail-oriented (doses/times) and careful with what I've been trying re the PEA/Selegiline.
After over a month of dose/time experimentation, even my "safe" regimen had problems. Following is an attempted repost that I've been putting everywhere I recommended PEA/Selegiline:
I THOUGHT that by experimenting I would find a safe PEA/Selegiline dose/time regimen.
I'm methodical and know enough about pharmacology, physiology and neurology to be dangerous .
THIS STUFF IS NOT SAFE. I HOPE I HAVEN'T HURT or will hurt anyone by what I've written about PEA/Selegiline.
Maybe....just maybe, if I can find a vasodilator and diuretic that will cancel out the vasoconstrictive and fluid retention properties of the combo, I'll write back.
Otherwise, my final word after 3 months using the combo is......
STAY AWAY FROM IT.
I don't know what in the world I'll do. Never found anything else like it.
I also kinda like life though and not having strokes from weird BP spikes or organ damage from fluid pressure. Mouth sores from the drying effect of the combo and rebound histamine spikes (PEA interferes with the enzyme that breaks down(?) histamine - NOT good for asthmatics or those with allergies.
X_ander, I can SOOOO relate to your condition, but I don't think PEA/Selegiline is the way to go. Again, if I can find countermeds for the dangerous effects, I'll post my findings.
Sorry
Jim
My apologies, but ignorance of what you're asking about keeps me from being able to help you Myco.
Jim
This is the end of the thread.
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