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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Jeroen on December 16, 2008, at 5:16:53
when i cut Seroquel XR in half;, it looses effect?
will it be Seroquel IR then when i cut the Seroquel XR 200 mg pill in half?
Posted by Phillipa on December 16, 2008, at 10:35:28
In reply to when i cut Seroquel XR in half;, it looses effect?, posted by Jeroen on December 16, 2008, at 5:16:53
Who cuts the pills the nurses? Still in hospital? Phillipa
Posted by Zyprexa on December 17, 2008, at 15:19:29
In reply to when i cut Seroquel XR in half;, it looses effect?, posted by Jeroen on December 16, 2008, at 5:16:53
I think you would have to crush it to make it like IR.
Posted by Jeroen on December 17, 2008, at 15:22:50
In reply to Re: when i cut Seroquel XR in half;, it looses effect?, posted by Zyprexa on December 17, 2008, at 15:19:29
hi zyprexa, hows it going
Posted by Zyprexa on December 17, 2008, at 20:25:47
In reply to Re: when i cut Seroquel XR in half;, it looses effect?, posted by Jeroen on December 17, 2008, at 15:22:50
Good, I guess.
Posted by yxibow on December 19, 2008, at 1:34:46
In reply to when i cut Seroquel XR in half;, it looses effect?, posted by Jeroen on December 16, 2008, at 5:16:53
> when i cut Seroquel XR in half;, it looses effect?
>
> will it be Seroquel IR then when i cut the Seroquel XR 200 mg pill in half?What on earth is the purpose of taking Seroquel XR, which is basically a patent extension, but maybe someone responds to it, and cutting it ?
Sorry to sound harsh but I don't understand why people want to cut extended release medication.
It could be Seroquel anything, there's no way of knowing, yes, best guess it would be Seroquel IR, but the plasma level could be all over the place.
The original Seroquel has already been proven to be effective as a single dose at night, regardless of its 6 hour half life, it is the plasma life.
-- Jay
Posted by Zyprexa on December 19, 2008, at 14:15:57
In reply to Re: when i cut Seroquel XR in half;, it looses effect? » Jeroen, posted by yxibow on December 19, 2008, at 1:34:46
Posted by yxibow on December 23, 2008, at 1:04:57
In reply to How do you make an extended release form? (nm), posted by Zyprexa on December 19, 2008, at 14:15:57
By making money with a patent? :0 A lot of the XRs, etc are patent extenders, there is some reason for certain formulations of agents though, like the extended Wellbutrin formulations tend to lower seizure problems.
Basically, the pill is made with multiple coatings I imagine, the first meant not to be breached as much by the hydrochloric acid in the stomach, which would be about a few hours I imagine, and slow the movement through the digestive tract and the blood-brain barrier...
-- actually here is one description of it that better describes it
http://en.wikipedia.org/wiki/Extended_release
-- Jay
Posted by Phillipa on December 23, 2008, at 19:41:25
In reply to Re: How do you make an extended release form? » Zyprexa, posted by yxibow on December 23, 2008, at 1:04:57
Jay what do you think of the new extended release luvox? Luvox has short half-life? Phillipa
Posted by yxibow on December 24, 2008, at 3:40:06
In reply to Re: How do you make an extended release form? » yxibow, posted by Phillipa on December 23, 2008, at 19:41:25
> Jay what do you think of the new extended release luvox? Luvox has short half-life? Phillipa
A patent extender basically now that the fleeing from Columbine has settled. Luvox doesn't have that short of a half life, its close to 15-16 hours. If you're not taking a large amount you can take the entire amount at one point, especially when titrating up from zero to whatever dose you may end up at. The plasma steady state counts more.
Its probably not a good idea to take 200 or 400mg at once which could affect a sudden rush in plasma levels, so its split up into two daily doses at higher levels.
-- Jay
Posted by Phillipa on December 24, 2008, at 18:51:14
In reply to Re: How do you make an extended release form? » Phillipa, posted by yxibow on December 24, 2008, at 3:40:06
yup when on 250mg took twice a day. Phillipa
This is the end of the thread.
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