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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Jeroen on November 5, 2008, at 9:23:11
hi, magnesium did nothing at all for the seroquel poop out effect, it even made my TD worse and sedation too
i am never taking this magnesium again
next in line is: Seroquel XR (no idea)
or Memantine (good chance)
Posted by JadeKelly on November 5, 2008, at 10:46:00
In reply to seroquel and magnesium failiure!, posted by Jeroen on November 5, 2008, at 9:23:11
> hi, magnesium did nothing at all for the seroquel poop out effect, it even made my TD worse and sedation too
>
> i am never taking this magnesium again
>
> next in line is: Seroquel XR (no idea)
> or Memantine (good chance)
Hi Joreoen, see my above response to your last post, 11/5 re: meds.
Hope it helps! Jade
Posted by Phillipa on November 5, 2008, at 12:07:35
In reply to Re: seroquel and magnesium failiure! » Jeroen, posted by JadeKelly on November 5, 2008, at 10:46:00
Jeroen magnesium and calcium directly influence bones and heart and are supplements. Magnesium is supposed to be calming. Also cause diarrhea in high doses. Sorry it didn't help The side effects. Love Phillipa
Posted by polarbear206 on November 6, 2008, at 16:36:56
In reply to seroquel and magnesium failiure!, posted by Jeroen on November 5, 2008, at 9:23:11
> hi, magnesium did nothing at all for the seroquel poop out effect, it even made my TD worse and sedation too
>
> i am never taking this magnesium again
>
> next in line is: Seroquel XR (no idea)
> or Memantine (good chance)Hey Jeroen
I still think you should trial Lithium.
Posted by bleauberry on November 6, 2008, at 18:10:18
In reply to seroquel and magnesium failiure!, posted by Jeroen on November 5, 2008, at 9:23:11
Magnesium helps a lot of people and is even a total cure for some. But me, it makes me feel a lot worse. More depressed, very lethargic. I think I get plenty in my choice of foods. I think I already have too much inhibitory stuff going on in my brain fighting off whatever mysterious excitation is going on that any more, such as magnesium, is just too much, or is working on the wrong pathways than the one causing the problems.
Lithium is similar to magnesium. Within the psychiatric world it would certainly make sense to give lithium a shot.
But, I've said it before and I'll say it again, a tricyclic antidepressant added to your seroquel is tops on my list as the best next thing you could do. I'm actually kind of puzzled and shocked why during 3 to 4 months within a hospital nobody has turned to the tried-and-true fairly reliable tricyclic family. I've seen enough case studies and such of people that reminded me of you who did best with an antipsychotic+TCA combo. Don't question why or how, just know that it has worked for others similar to you...psychosis+depression+schizophrenia+treament resistant...when all the other things that seemed to make more sense didn't work.
Posted by Jeroen on November 7, 2008, at 2:10:56
In reply to Re: seroquel and magnesium failiure!, posted by polarbear206 on November 6, 2008, at 16:36:56
nobody wants to prescribe that to me
Posted by Jeroen on November 7, 2008, at 2:13:21
In reply to Re: seroquel and magnesium failiure!, posted by bleauberry on November 6, 2008, at 18:10:18
thanks! what about trazodone?
Posted by bleauberry on November 7, 2008, at 19:46:23
In reply to to blueberry, posted by Jeroen on November 7, 2008, at 2:13:21
> thanks! what about trazodone?
My guess is trazodone wouldn't be the one. But ya know, it is easy to be totally wrong, as your doctors have seen with their own choices.
Overall trazodone just doesn't seem to have enough oomph in my opinion, and maybe that is why it is used mostly as a sleep agent? I can't even think of the last time anyone ever said trazodone was their magic medicine. Happens with all the others though.
In that same family though, serzone sounds like a better choice. But going through a trial of two to three tricyclics makes a lot more sense to me, just based on other case reports similar to you. Amitriptyline, nortriptyline, imipramine, possibly desipramine. I mean, all you would need is about 2 weeks on each one to give them a good feel. If you don't get worse on one, or improve slightly, then keep going with it for more time. If you do get worse, switch to another one straight across without any washout.
When I read about tough cases like yours, it seems like tricyclics keep coming up. While most of these other meds we take are fairly fine tuned in what they do, the tricyclics hit so many different things. I mean, for example, hyper histamine can be the same as psychosis. Hyper choline can too. Tricyclics are anti both of those. Maybe seroquel worked for a short time because it was such a strong antihistimine, but tolerance developed to that. Tolerance that maybe could be avoided if the anti-histamine effect was coming from two different directions from two different drugs acting on a wider coverage of the various different histamine receptors? I am just thinking out loud.
Posted by Jeroen on November 10, 2008, at 15:13:32
In reply to Re: to blueberry » Jeroen, posted by bleauberry on November 7, 2008, at 19:46:23
hi there, thanks for your info
doctors here dont switch and do that, they rather want me to stick with something i feel down with
too bad, its like a punishment, everybody complains
This is the end of the thread.
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