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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 21 of 21. This is the beginning of the thread.
Posted by linkadge on October 21, 2008, at 6:13:59
Its a fact of life. Stuff stops working.
Linkadge
Posted by linkadge on October 21, 2008, at 6:15:30
In reply to Folks, you've got to get over pooped out drugs, posted by linkadge on October 21, 2008, at 6:13:59
A drug could have felt like God's gift to mankind 2 years ago, but if its not working now then thats all that matters.
Linkadge
Posted by bulldog2 on October 21, 2008, at 8:43:54
In reply to Folks, you've got to get over pooped out drugs, posted by linkadge on October 21, 2008, at 6:13:59
> Its a fact of life. Stuff stops working.
>
> LinkadgeGood post. The way I look at life is some periods of remission are better than none.I for one don't beat myself up with "would I have been better had I never started drugs". My problems are so hard wired and started so young in life that talk therapy wasn't going to put a dent in my emotional life.So I've cycled drugs for almost 40 years and that's a fact of life. Had it not been for benzos I would never have had a fairly productive work life. I suffer from social/phobia/panic anxiety. CBT just didn't cut it and talk therapy and helped me understand it but didn't stop it.
Oh yes and I was always very physically active and took all the latest cure all supplements and vitamins and minerals and that didn't cure me.
Posted by NewQuestions on October 21, 2008, at 10:52:24
In reply to Re: Folks, you've got to get over pooped out drugs, posted by bulldog2 on October 21, 2008, at 8:43:54
It much more complicated than that. "Poop out" comes in many different forms. There are:
1. Drugs that stop working, but you can use other similar drugs.
2. Drugs that stop working, but you can use other more exotic drugs.
3. Drugs that stop working, and seem to have changed your brain so you can't use any other drugs, because either they don't work or because of the side effects.
Obviously, No. 3 is the worst. Additionally, what if you fall into No. 3 and you can't go off all the drugs because you do not snap back to your pre-drug state? In other words, lets say on a scale of 1 through 10 your brain naturally produced serotonin at a 5, but then after the drugs, it produces sertonin at a 3. Then you can't be on the drugs because they don't work or because of the side effects but you can't be off the drugs because of the way the drugs changed you.
Posted by Phillipa on October 21, 2008, at 11:03:42
In reply to Re: Folks, you've got to get over pooped out drugs, posted by NewQuestions on October 21, 2008, at 10:52:24
What's a remission? Haven't felt normal in over 13 years and have tried many drugs anc categories. Some side effects were so awful had to stop and the one with no side effects luvox now can't get off the 50mg tiny dose but it doesn't do anything my brain wants it after all these years and benzos were wondere drugs at very low doses for me till about four years ago. I just try and push on and it's getting harder. Many poo poo my thyroid but seriously that's when everything went down hill. Love Phillipa
Posted by linkadge on October 21, 2008, at 11:28:10
In reply to Re: Folks, you've got to get over pooped out drugs, posted by bulldog2 on October 21, 2008, at 8:43:54
I'm not condeming medications, I just think that people need to let go of meds that once worked but are clearly no longer working.
I took celexa once and it worked great, the next time I took it, it did nothing. Its not going to help if I take it for another two years and complain the whole time about why I can't feel like I did when I first took it.
I say move on.
Linkadge
Posted by linkadge on October 21, 2008, at 11:31:39
In reply to Re: Folks, you've got to get over pooped out drugs, posted by NewQuestions on October 21, 2008, at 10:52:24
I guess I a just concerned that some people are unable to accept when a drug is no longer working (it happens to me too).
Sure it sucks when a med works and you feel great and then it stops, but I don't think its reasonable to keep taking a drug that has not been working for a long time and expect it to start magically working.
Posted by Bob on October 21, 2008, at 12:10:08
In reply to Re: Folks, you've got to get over pooped out drugs, posted by NewQuestions on October 21, 2008, at 10:52:24
> It much more complicated than that. "Poop out" comes in many different forms. There are:
>
> 1. Drugs that stop working, but you can use other similar drugs.
>
> 2. Drugs that stop working, but you can use other more exotic drugs.
>
> 3. Drugs that stop working, and seem to have changed your brain so you can't use any other drugs, because either they don't work or because of the side effects.
>
> Obviously, No. 3 is the worst. Additionally, what if you fall into No. 3 and you can't go off all the drugs because you do not snap back to your pre-drug state? In other words, lets say on a scale of 1 through 10 your brain naturally produced serotonin at a 5, but then after the drugs, it produces sertonin at a 3. Then you can't be on the drugs because they don't work or because of the side effects but you can't be off the drugs because of the way the drugs changed you.
Very insightful post. I'm in category 3 unfortunately. Actually it's sort of a modified cat 3. The drugs that used to "work" on maybe a 7 out of 10 scale are now at a 1 or 2. However, and this is important, they are not a zero. Then if I try to come off of them, all hell breaks loose and my condition deteriorates into an eventual life threatening situation.To say the least, my body stop bouncing back to pre-drug states many years ago, but that might be irrelevant since my pre-drug state was unacceptable.
- Bob
Posted by Bob on October 21, 2008, at 12:12:40
In reply to Re: Folks, you've got to get over pooped out drugs, posted by Phillipa on October 21, 2008, at 11:03:42
> What's a remission? Haven't felt normal in over 13 years and have tried many drugs anc categories. Some side effects were so awful had to stop and the one with no side effects luvox now can't get off the 50mg tiny dose but it doesn't do anything my brain wants it after all these years and benzos were wondere drugs at very low doses for me till about four years ago. I just try and push on and it's getting harder. Love Phillipa
Exactly. Me too, but with Celexa instead of Luvox.
Posted by Phillipa on October 21, 2008, at 12:45:20
In reply to Re: Folks, you've got to get over pooped out drugs » Phillipa, posted by Bob on October 21, 2008, at 12:12:40
Really I thought I was the only one? What's your functioning level. I'm very scared to go out alone and get tired very fast. Phillipa
Posted by Jeroen on October 21, 2008, at 14:37:53
In reply to Re: Folks, you've got to get over pooped out drugs, posted by Phillipa on October 21, 2008, at 11:03:42
hey philippa, 13 years, i am 10 years so 3 years to go then :(
im taking magnesium with seroquel who knows theres a 10% chance it will help it kick in againotherwise i can try XR, 400 mg or 800 mg
Posted by Phillipa on October 21, 2008, at 15:04:37
In reply to To Philippa, posted by Jeroen on October 21, 2008, at 14:37:53
Jeroen you're so young what age when started them? I thought you were early 20's? Love Phillipa
Posted by cumulative on October 21, 2008, at 18:08:07
In reply to Folks, you've got to get over pooped out drugs, posted by linkadge on October 21, 2008, at 6:13:59
And instead (eventually) tried memantine, which prevents it from doing so for me. The combination has been better than anything else I have tried, for 13 weeks now.
Posted by Bob on October 21, 2008, at 19:38:39
In reply to Re: Folks, you've got to get over pooped out drugs » Bob, posted by Phillipa on October 21, 2008, at 12:45:20
> Really I thought I was the only one? What's your functioning level. I'm very scared to go out alone and get tired very fast. Phillipa
I'm at a pretty low level. I've been diabled from my job for a few years ago. My mornings are always pretty bad, and sometimes the rest of the day isn't so good either. A lot of fatigue and apathy, along with mostly physical manifestations of anxiety.
Posted by linkadge on October 21, 2008, at 20:47:35
In reply to I'm glad I didn't get over amphetamine pooping out, posted by cumulative on October 21, 2008, at 18:08:07
Well goodey for you.
Linkadge
Posted by Jeroen on October 22, 2008, at 1:12:57
In reply to Re: I'm glad I didn't get over amphetamine pooping out » cumulative, posted by linkadge on October 21, 2008, at 20:47:35
there is evidence that it works with SSRI and Ritalin alike agents, i hope it works with seroquel too
Posted by Jeroen on October 22, 2008, at 2:22:16
In reply to Re: Folks, you've got to get over pooped out drugs » Phillipa, posted by Bob on October 21, 2008, at 19:38:39
hi, is this safe, im taking Seroquel 100 mg twice daily, Abilify 10 mg, and Magnesium 400 mg once daily
Posted by Zyprexa on October 22, 2008, at 14:04:08
In reply to is this safe?, posted by Jeroen on October 22, 2008, at 2:22:16
How is the seroquel going?
Posted by Jeroen on October 22, 2008, at 14:36:16
In reply to Re: Looks safe to me » Jeroen, posted by Zyprexa on October 22, 2008, at 14:04:08
better then the rest, thanks
im waiting for the 4 minutes it will work lol and make me feel great for only 4 minutes
im taking magnesium 400 mg with it, theres 10% chance it will kick in :)
Posted by cumulative on October 22, 2008, at 21:13:09
In reply to Re: I'm glad I didn't get over amphetamine pooping out » cumulative, posted by linkadge on October 21, 2008, at 20:47:35
> Well goodey for you.
Haha. I'm just saying there can be value to ... keeping at it, I guess.
Posted by okydoky on October 25, 2008, at 21:57:34
In reply to Re: I'm glad I didn't get over amphetamine pooping out, posted by cumulative on October 22, 2008, at 21:13:09
Interesting. I just procured some Parnate. I took Parnate for several years and it pooped out completely about 14 years ago. My old pdoc used to have me try it every few years. It's been about 4 years now so I thought I'd try it again.
Think it's a waste of time and hope and money? I try other things, they just have not worked so I try it again evey few years. Has anyone heard of a drug working again after years? I used to go on drug holidays from Parnate for several months at a time and that worked for a few years.
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