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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Bob on August 4, 2008, at 12:11:15
Does anyone know if there is a medical or scientific term for when a psychiatric drug or combo stops working after a period of time during which it was at least partially effective? I know that the common slang term is poop-out, but is there another expression that pdocs would use other than, stopped working?
Posted by Phillipa on August 4, 2008, at 12:14:58
In reply to Terminology for 'poop out'?, posted by Bob on August 4, 2008, at 12:11:15
I don't know. I think this is when the docs start adding things or changing meds. Anyone know if they believe in poopout? As when working in psych they always said that the patient stopped taking the med and we as nurses believed them. What I know now that I didn't know then is phenominal thanks to babble meds. Phillipa
Posted by Bob on August 4, 2008, at 12:23:33
In reply to Re: Terminology for 'poop out'? » Bob, posted by Phillipa on August 4, 2008, at 12:14:58
> I don't know. I think this is when the docs start adding things or changing meds. Anyone know if they believe in poopout? As when working in psych they always said that the patient stopped taking the med and we as nurses believed them. What I know now that I didn't know then is phenominal thanks to babble meds. Phillipa
My God. If they're not going to believe that a med can stop working then the situation might be much much worse than I could have imagined.
Posted by Phillipa on August 4, 2008, at 12:28:42
In reply to Re: Terminology for 'poop out'? » Phillipa, posted by Bob on August 4, 2008, at 12:23:33
Remember this was l3 years ago. I think I'll google the term and see what it says? I hope docs have accepted that a med can stop working they know benzos do. Also they change meds to another similar one. Let me see. Phillipa I'm wrong I'm sure I hope I am. Forgive me If I scared you. I scare me all the time. Phillipa
Posted by Phillipa on August 4, 2008, at 12:33:12
In reply to Re: Terminology for 'poop out'? » Phillipa, posted by Bob on August 4, 2008, at 12:23:33
Goggle has a lot here's one. A Discussion forum. Phillipa
PAXIL POOP OUT,SWITCHING SSRIS - Family Medicine - MedHelp
Posted by Justherself54 on August 4, 2008, at 15:09:47
In reply to Terminology for 'poop out'?, posted by Bob on August 4, 2008, at 12:11:15
> Does anyone know if there is a medical or scientific term for when a psychiatric drug or combo stops working after a period of time during which it was at least partially effective? I know that the common slang term is poop-out, but is there another expression that pdocs would use other than, stopped working?
I think the term is tachyphylaxis. If you search the web you'll find lots of sites.
Posted by SLS on August 4, 2008, at 15:58:38
In reply to Terminology for 'poop out'?, posted by Bob on August 4, 2008, at 12:11:15
Tachyphylaxis ?
- Scott
Posted by Bob on August 4, 2008, at 16:31:02
In reply to Re: Terminology for 'poop out'?, posted by SLS on August 4, 2008, at 15:58:38
> Tachyphylaxis ?
>
>
> - ScottIt apparently refers to the tendency for some drugs to cause a response with the initial dose, but then rapidly degrade into non-response. I don't think it has anything to do with psychiatric drugs in particular.
IMO, psychiatry needs a term to refer to the poop-out phenomenon, since it appears with frequency and regularity.
- Bob
Posted by Justherself54 on August 4, 2008, at 17:43:16
In reply to Re: Terminology for 'poop out'?, posted by SLS on August 4, 2008, at 15:58:38
> Tachyphylaxis ?
>
>
> - ScottJust trying my best to help a poster with a question. If you google tachyphylaxis and anti-depressants there are lots of references to it.
That's all I have to say.
Posted by SLS on August 4, 2008, at 18:59:19
In reply to Re: Terminology for 'poop out'? » SLS, posted by Bob on August 4, 2008, at 16:31:02
It is pretty funny, isn't it? Such great minds in the medical field have not come up with anything more technical.
- Scott
Posted by Larry Hoover on August 4, 2008, at 20:06:00
In reply to Terminology for 'poop out'?, posted by Bob on August 4, 2008, at 12:11:15
To no one in particular, tachyphylaxis is mis-used in the context of antidepressants. Tachyphylaxis is a rapid process. In the context of ADs, I think that desensitization is the proper concept, but it's not commonly used. Even tolerance would be a more appropriate term than tachyphylaxis.
That said, language evolves. And the victory apparently goes to tachyphylaxis.
Lar
Posted by SLS on August 4, 2008, at 20:28:22
In reply to Re: Terminology for 'poop out'?, posted by Larry Hoover on August 4, 2008, at 20:06:00
Hi Larry.
Yes. You are right. I left a question mark after the term because I didn't feel it was the best match as a synonym.
In my case, though, I would call my pattern of 3-day responses to antidepressant monotherapy as being tachyphylactic. "Tolerance" sounds appropriate, all things considered. Still, there is something about the term "poop-out" that hits the target.
- Scott
> To no one in particular, tachyphylaxis is mis-used in the context of antidepressants. Tachyphylaxis is a rapid process. In the context of ADs, I think that desensitization is the proper concept, but it's not commonly used. Even tolerance would be a more appropriate term than tachyphylaxis.
>
> That said, language evolves. And the victory apparently goes to tachyphylaxis.
>
> Lar
This is the end of the thread.
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