Psycho-Babble Medication Thread 826706

Shown: posts 1 to 5 of 5. This is the beginning of the thread.

 

Parnate vs. Nardil

Posted by maco11 on May 1, 2008, at 21:46:09

I am new to this forum but not very new to depression.

I started taking Parnate about 15 years ago after being on several different meds, both tric and SSRI's and a multitude of combinations through my late teens and into my early 20's. I was giving up-I lost all will to go on. Couldn't eben get out of bed and God forbid hold down a job.

In a last desparate attempt to 'live', I switched psych's and was given Parnate after he diagnosed me with Atypical Depression. Parnate saved my life back then and could care less about side affects or special diets. I mean, depression was the absolute worse side affect of life anyone could have, so watching what I ate was not a problem- because I had my life back.

Anyway, I spent years on Parnate but seemed in some weird way to build up a tolerence to my dosage. I felt that I had to increase the amount to achieve the same affect. Went up to 100mg a day- Eventually, some side affects did catch up to me, so I went on to numerous combo's of Zoloft w/ Adderall and Klono (can't spell half of these meds)..so now, my new pdoc wants to put me on Nardil.

I've researched this MAOI but seemed to be a little confused as to the real difference between the Parnate I used to take and Nardil. They are both MAOI's, one MAOI-A and one B.

Could someone share the overall difference or how they felt when taking Nardil, then at some later time, Parnate (or vice versa)or maybe was the effect the same or similar

 

Re: Parnate vs. Nardil » maco11

Posted by Phillipa on May 1, 2008, at 23:20:03

In reply to Parnate vs. Nardil, posted by maco11 on May 1, 2008, at 21:46:09

Welcome to babble see you're new to the forum. A wealth of information here. I personally can not answer your questions but am sure someone will soon. Again welcome!!!! Love Phillipa

 

Re: Parnate vs. Nardil » maco11

Posted by Quintal on May 2, 2008, at 11:47:26

In reply to Parnate vs. Nardil, posted by maco11 on May 1, 2008, at 21:46:09

Put simply Parnate is more of an amphetamine-like stimulant (but not everyone feels this effect), while Nardil is more sedating. Nardil also has GABAergic metabolites that help anxiety, a bit like a benzo. Sexual problems are much more common with Nardil than Parnate, as is weight gain. I get the impression Nardil users are more prone to severe hypotension and consitaption. Both of them tend to cause insomnia.

Q

 

Re: Parnate vs. Nardil

Posted by undopaminergic on May 2, 2008, at 14:08:36

In reply to Re: Parnate vs. Nardil » maco11, posted by Quintal on May 2, 2008, at 11:47:26

Also, Parnate is less likely to have adverse effects on the liver, but it appears to have a higher risk of hypertensive attacks than Nardil.

 

Re: Parnate vs. Nardil

Posted by maco11 on May 3, 2008, at 19:15:20

In reply to Re: Parnate vs. Nardil, posted by undopaminergic on May 2, 2008, at 14:08:36

Thanks for this info., I'm a little torn on whether I should even start Nardil or simply pester my doc for Parnate again. Everyone's knowledge and experience with this is helpful.
But, I do know that even though Parnate helped me so much in the past, I was confused alot, had a very hard time focusing on anything. This scares me as I have a very demanding job. I guess I just have to weigh out the pros and cons of both. Either way, MAOI's have been so much more affective in treating my depression.


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