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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by dapper on December 7, 2007, at 3:38:15
So, who has solid research and facts on the newest form of medication known as Valdoxan? Supposedly, its proving to be as effective, if not more, than effexor. However, it actually aids in proper sleep, rather than disturbes REM sleep, like most SSRI's or SNRI's. So no daytime lethargy, and no sexual side effects either. Too good to be true? It's making me wonder. However, prozac was probably too good to be true for many when it debuted. Just wanted some insight from others and opinions. I guess its in the middle of FDA approval from Novartis.
Posted by Netch on December 7, 2007, at 10:16:32
In reply to A new medication in the works? : ), posted by dapper on December 7, 2007, at 3:38:15
Valdoxan looks promising
Posted by Phillipa on December 7, 2007, at 11:52:29
In reply to Re: A new medication in the works? : ), posted by Netch on December 7, 2007, at 10:16:32
Wasn't luvox from France and servier? Phillipa
Posted by Bob on December 7, 2007, at 21:31:50
In reply to A new medication in the works? : ), posted by dapper on December 7, 2007, at 3:38:15
> So, who has solid research and facts on the newest form of medication known as Valdoxan? Supposedly, its proving to be as effective, if not more, than effexor. However, it actually aids in proper sleep, rather than disturbes REM sleep, like most SSRI's or SNRI's. So no daytime lethargy, and no sexual side effects either. Too good to be true? It's making me wonder. However, prozac was probably too good to be true for many when it debuted. Just wanted some insight from others and opinions. I guess its in the middle of FDA approval from Novartis.
Is this supposed to become available in the U.S.?
Posted by 10derHeart on December 7, 2007, at 23:50:39
In reply to Re: A new medication in the works? : ) » dapper, posted by Bob on December 7, 2007, at 21:31:50
You would hope so......this site has a paragraph on it. Supposedly, Novartis will finish required studies and "file" the drug this year (2007)
http://www.drugresearcher.com/news/ng.asp?id=79754-novartis-tifacogin-fingolimod-mycograb-aeb
How much time between drug company filing, through FDA approval to finally on the market? Beats me. Anyone know?
Posted by Abby Cunningham on December 8, 2007, at 21:41:09
In reply to Re: A new medication in the works? : ) » dapper, posted by Bob on December 7, 2007, at 21:31:50
> > So, who has solid research and facts on the newest form of medication known as Valdoxan? Supposedly, its proving to be as effective, if not more, than effexor. However, it actually aids in proper sleep, rather than disturbes REM sleep, like most SSRI's or SNRI's. So no daytime lethargy, and no sexual side effects either. Too good to be true? It's making me wonder. However, prozac was probably too good to be true for many when it debuted. Just wanted some insight from others and opinions. I guess its in the middle of FDA approval from Novartis.
>
>
> Is this supposed to become available in the U.S.?
>
See this thread and links:
http://www.dr-bob.org/babble/20071115/msgs/795849.html
Valdoxan is still in open label studies; the university of MA is doing one right now which I wanted to get in on, however you must quit all other psych meds and not be seeing a therapist : a perfect patient for Novartis is a depressed person who has not been on meds and is not seeing a therapist!! How many of those kinds of people are around? LOL....I don't think this study will recruit that many people. They taper people off current meds (probably way too fast) then put them on valdoxan; how the heck can they tell what is withdrawal from other meds and what is side effects from valdoxan or is it helping. Seems they would do better with a previously unmedicated brain. Good luck to them.
Posted by Bob on December 9, 2007, at 11:17:45
In reply to Re: A new medication in the works? : ), posted by Abby Cunningham on December 8, 2007, at 21:41:09
What is an "open label study"?
Posted by deniseuk190466 on December 9, 2007, at 12:17:13
In reply to Re: A new medication in the works? : ) » Abby Cunningham, posted by Bob on December 9, 2007, at 11:17:45
I was wonderng why you have to quit all other medication to go on the trial. Are they Contradicted if taken together?
Surely if the meds you are taking are helping a little but not enough by adding this med you would know if it makes the difference or not.
I wanted to try and get on a Ketamine trial but for that you seem to have to wean off all other meds to (which is not something I feel I can do) but I don't understand why I would have to come off all other medication.
Denise
Posted by yxibow on December 9, 2007, at 17:33:20
In reply to Re: A new medication in the works? : ) » Abby Cunningham, posted by Bob on December 9, 2007, at 11:17:45
> What is an "open label study"?
One in which the doctors and patients know what medication they are receiving as opposed to a double blind trial.
Posted by Racer on December 9, 2007, at 20:59:10
In reply to Why do you have to quit all meds?, posted by deniseuk190466 on December 9, 2007, at 12:17:13
> I was wonderng why you have to quit all other medication to go on the trial. Are they Contradicted if taken together?
>
>No, it's nothing to do with whether or not other drugs are contraindicated with the drug being studied. The point of the trial is to see if the study drug is effective -- which means you have to test it alone. It doesn't make a huge amount of sense, from the drug company's standpoint, to run tests to see if their drug is only effective if combined with other drugs -- they have to prove that the drug is valuable on its own.
Thus, you have to stop all other drugs in order to be included in the study.
Does that make more sense?
Posted by Deniseuk190466 on December 13, 2007, at 14:02:08
In reply to Re: Why do you have to quit all meds? » deniseuk190466, posted by Racer on December 9, 2007, at 20:59:10
Racer,
Yes it does and I did realise that but I was talking to a Doctor in the States about going on this Ketamine trial and I would like to participate but the thought of coming off all medication before 5 weeks beforehand (which is what it could amount to) kills me. Everytime I try coming off I just feel awful, it's horrible an it doesn't get any better. If I came off them and it was just two weeks of feeling bad then it wouldn't be so bad but it's not just for two weeks, it's for as long as I am off them.
I thought maybe they could at least let me take a little bit of zyprexa or something every now and again just to help see me through. I can't see the harm in that.
I hate being like this, I feel like such a junkie. But there is a limit to how long I'm prepared to suffer.
Denise
This is the end of the thread.
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