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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by KarenRB53 on October 16, 2007, at 18:37:28
My pdoc was suggesting that I try Sinequin and I have never heard of it. Has anyone used it? He's trying to find an AD that will not effect high blood pressure.
Posted by Racer on October 16, 2007, at 18:44:41
In reply to Sinequin, posted by KarenRB53 on October 16, 2007, at 18:37:28
I took a very low dose of Sinequan many years ago for pain. I couldn't tolerate it, because it lowered my blood pressure too much, and the dose was below therapeutic for depression, anyway, so I can't tell you whether it was effective.
It's a tricyclic, hits NE and 5HT, as well as some of the histamine receptors and I think acetylcholine. I know I've heard of it being well tolerated, and I can't help but think it won't raise blood pressure... The generic name is doxepin, if that helps you at all.
If you haven't tried a tricyclic, it's probably well worth trying.
Good luck.
Posted by Phillipa on October 16, 2007, at 19:38:51
In reply to Sinequin, posted by KarenRB53 on October 16, 2007, at 18:37:28
What other classes of meds have you tried in the past? Phillipa
Posted by alienatari on October 17, 2007, at 0:22:59
In reply to Sinequin, posted by KarenRB53 on October 16, 2007, at 18:37:28
I was on it, at 150mg at the most. Made me quite dizzy sometimes. Did help me sleep though. Didnt really help my depression but no antidepressant has so maybe thats just me.
Posted by KarenRB53 on October 17, 2007, at 7:45:09
In reply to Re: Sinequin, posted by alienatari on October 17, 2007, at 0:22:59
> I was on it, at 150mg at the most. Made me quite dizzy sometimes. Did help me sleep though. Didnt really help my depression but no antidepressant has so maybe thats just me.
Were you on it for long and did it make you gain weight? I know the tricyclics are famous for weight gain. Do you mind my asking if you're on any meds for blood pressure?
Thanks, Karen
Posted by KarenRB53 on October 17, 2007, at 7:52:01
In reply to Re: Sinequan » KarenRB53, posted by Racer on October 16, 2007, at 18:44:41
> I took a very low dose of Sinequan many years ago for pain. I couldn't tolerate it, because it lowered my blood pressure too much, and the dose was below therapeutic for depression, anyway, so I can't tell you whether it was effective.
>
> It's a tricyclic, hits NE and 5HT, as well as some of the histamine receptors and I think acetylcholine. I know I've heard of it being well tolerated, and I can't help but think it won't raise blood pressure... The generic name is doxepin, if that helps you at all.
>
> If you haven't tried a tricyclic, it's probably well worth trying.
>
> Good luck.No,I've never tried a tricyclic before. They're famous for weight gain and that I don't want. What dosage were you taking and do you take meds for high blood pressure?
Thanks, Karen
Posted by KarenRB53 on October 17, 2007, at 8:02:10
In reply to Re: Sinequin » KarenRB53, posted by Phillipa on October 16, 2007, at 19:38:51
> What other classes of meds have you tried in the past? Phillipa
I was on Prozac for over 10 yrs and just tapered off. I wanted to try the Ensam patch but pdoc is afraid because I have high blood pressure (but well under control with meds). He has also suggested Imipramine but these are tricyclics and famous for weight gain which I don't want. I'm trying to lose the weight I put on with Prozac.
Karen
Posted by Racer on October 17, 2007, at 9:38:40
In reply to Re: Sinequan » Racer, posted by KarenRB53 on October 17, 2007, at 7:52:01
> No,I've never tried a tricyclic before. They're famous for weight gain and that I don't want. What dosage were you taking and do you take meds for high blood pressure?
> Thanks, Karen
>
>This was more than twenty years ago, so I might be wrong, but I think I was taking 25mg -- it was not for depression, and that's below therapeutic levels for depression.
No, no blood pressure meds -- my normal BP is about 90/60, so a "blood pressure" med for me would probably RAISE it so that I didn't fall down so much...
TCAs are notorious for a lot of side effects, including weight gain. Desipramine is supposed to be pretty weight/blood pressure neutral, if that helps. For weight gain, you might talk to your doctor about medications to mitigate it. Sometimes an acid reducer helps, other times other medications -- like Topomax -- can help.
Good luck.
Posted by linkadge on October 17, 2007, at 13:30:55
In reply to Re: Sinequan » KarenRB53, posted by Racer on October 17, 2007, at 9:38:40
I've tried doxapin and it is fairly good. It is a bit of a deleriant, but it helps depression.
Linkadge
Posted by KarenRB53 on October 17, 2007, at 14:24:48
In reply to Re: Sinequan, posted by linkadge on October 17, 2007, at 13:30:55
> I've tried doxapin and it is fairly good. It is a bit of a deleriant, but it helps depression.
>
> LinkadgeReally!! I'm spacey enough, I don't need any help. Did you stop taking it for that reason?
Karen
Posted by linkadge on October 18, 2007, at 12:42:20
In reply to Re: Sinequan » linkadge, posted by KarenRB53 on October 17, 2007, at 14:24:48
No, I stopped because I couldn't get a doctor to represcribe it. I thought it was a good med, I would have continued.
Linkadge
This is the end of the thread.
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