![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 11 to 35 of 35. Go back in thread:
Posted by Jeroen on July 14, 2007, at 19:05:23
In reply to Re: neuroleptic magniulan syndrome » KayeBaby, posted by Phillipa on July 14, 2007, at 18:11:50
sorry dont know what to say nor to do,
ed is aware of my situation, i think bob is too..
thanks for concern, i am in not so good shape
Posted by Phillipa on July 14, 2007, at 22:29:50
In reply to Re: neuroleptic magniulan syndrome, posted by Jeroen on July 14, 2007, at 19:05:23
Well if Ed knows all is okay. Love Phillipa
Posted by stargazer2 on July 15, 2007, at 8:35:13
In reply to stargazer, posted by Jeroen on July 14, 2007, at 16:45:01
Anything that will help you is important to do or say. Do the doctors there mention NMS as the cause of your fever? Do you have rigidity? You have to be very careful with any of the neuroleptics and hopefully you are not on any right now or possibly any antypicals in the future, unless at very low doses. That was one of the known diagnoses I feared when my doctor put me on AP's. I would not go above a certain dosage with abilify.
Good luck with resolving this situation you are in...SG
Posted by Fivefires on July 15, 2007, at 19:31:07
In reply to Info on NMS (neuroleptic malignant syndrome), posted by stargazer2 on July 14, 2007, at 16:42:55
I think this is what happened to my grandmother.
She was given Haldol in an ER.
Once NMS is recognized, is the most important and immediate treatment, the removal of the neuroleptic medication?
And, can that even sometimes 'be too late'?
My grandmother 'never got her mind back'.
She was still energetic and her mind was clear as a bell, the day before.
I apologize if these are questions you cannot answer yourself, but maybe you can, so thanks much.
5f
Posted by Fivefires on July 15, 2007, at 21:16:37
In reply to Info on NMS (neuroleptic malignant syndrome), posted by stargazer2 on July 14, 2007, at 16:42:55
I failed to address my ?s 2 Stargazer by name, so following up her post again, and adding one more question.
I'm so concerned, because, 1) A lot of very ill people were on babble tonight :(, and 2) I've been thinking of trying a low dose atypical antipsychotic for my TRD.
My add'l ? - Could Haldol alone cause neuroleptic malignant syndrome, or more likely the dopamine, or both?
tyshareurknowledge, 5f
ps: I'm now thinking a mood stabilizer may be something safer to ponder.
Posted by Jeroen on July 16, 2007, at 3:58:06
In reply to Re: Info on NMS (neuroleptic malignant syndrome) » stargazer2, posted by Fivefires on July 15, 2007, at 21:16:37
mood stablizer thats what i got it from
lamictal, still having fever
Posted by stargazer2 on July 16, 2007, at 5:44:07
In reply to Re: Info on NMS (neuroleptic malignant syndrome) » stargazer2, posted by Fivefires on July 15, 2007, at 21:16:37
5f, the combination of haldol and sinemet were the cause of my father's NMS. He was given haldol, which prevents dopamine release and sinemet, which promotes dopamine release (since that chemical is soo low in Parkinsonism) and the removal of the much needed dopamine precipitated the syndrome. It was known he was on Sinemet, so it was a medical error to give him Haldol and this was done at Yale, a top 10 hospital in the country. If it was missed there, it would be missed most places unless someone had personal experience with it.
So much is NOT known about how the AP work and in combination with the various other drugs so many of us take, it can be a recipe for disaster. Even my own doctor prescribes AP without thinking about the side effects of NMS.
Removal of the drug, typically an antipsycotic, is the first order of business, followed by the administration of bromcristine and another drug (listed in the article under my post above describing the syndrome and the treatment).
Using an AP on it's own can cause NMS and I think the article said only 0.5-1% develop and 90% develop it within the first two weeks of use. My fear is that no one knows much about it, look at Jereon, and so many others where it is missed routinely.
I took Abilify, Risperdal, Seroquel and zyprexa myself for TRD and try to never do this unless I'm in a real crisis, so I avoid them if at all possible due to the risk, even minor, of NMS.
They have never done much for me in terms of depression resolution. I just stopped abilify on my own due to ineffectiveness, although I'm sure my pdoc would have been happy to see me continue to increase the Abilify rather than the wellbutrin or nardil, I'm not sure why with the seriousness of the side effects.Are the drug companies offering the docs incentives to prescribe the AP's since abify costs $600 for a month's supply and did nadda for me?
Remember, a fever is the classic sign of the syndrome, so an unexplained fever with rigidity is what will usually occur first.
SG2
Posted by Jeroen on July 16, 2007, at 8:33:17
In reply to Re: Info on NMS /5f, posted by stargazer2 on July 16, 2007, at 5:44:07
this is bad, very bad, even the geodon
Posted by Fivefires on July 16, 2007, at 16:12:11
In reply to Re: Info on NMS /5f, posted by stargazer2 on July 16, 2007, at 5:44:07
Tks so much sg2.
I've either overlooked a discussion of NMS b4 now, or was in one and didn't understand the magnitude.
This is a real good reason to say no to APs or mood stabilizers for depression, awa Haldol (a tranquilizer I believe).
No one's gettin' @ my dopamine and that's final!
Maybe I'm already depriving myself of some by taking Xanax, but it's either this or Valium 4me at this time.
My anxiety is my mental illness.
This is a print - author unknown.
Glad you were there for your father.
All my best to Jereon.
YouToo, 5f
Posted by Phillipa on July 16, 2007, at 19:18:19
In reply to Re: Info on NMS. » stargazer2, posted by Fivefires on July 16, 2007, at 16:12:11
Haldol is a major tranquilzer and can also cause TD. I don't think a mood stabalizer such as lamictal, tegretol, depakote,lithium could cause NLS. Love Phillipa
Posted by Fivefires on July 16, 2007, at 20:16:41
In reply to Re: Info on NMS. » Fivefires, posted by Phillipa on July 16, 2007, at 19:18:19
Yeah Phillipa?
I thought someone had posted a mood stabilizer had precipitated NMS, though I could very well be wrong. I'm upset about a life situation here today. I think there were two threads going at the same time on pb yesterday re: NMS.
I'm full of ?s and searching for answers.
Feeling very med skiddish today.
tks, 5f
Posted by stargazer2 on July 16, 2007, at 21:04:10
In reply to Re: Info on NMS. » Fivefires, posted by Phillipa on July 16, 2007, at 19:18:19
FYI...Haldol is classified as an antipsychotic, not a major or minor tranquilizer...SG
Posted by Phillipa on July 16, 2007, at 21:26:33
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 16, 2007, at 21:04:10
SG2 I know it's a typical antipsychotic but didn't they used to classify it as a major tranquiller in the past? Love Phillipa ps we used to give haldol and ativan to out of control patients they stopped the haldol as BP could get so low. Love Phillipa
Posted by Phillipa on July 16, 2007, at 21:39:48
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 16, 2007, at 21:04:10
SG2 also used for intracctable hiccups. And mania until the mood stabalizer particularily lithium kicks in. Love Phillipa
Posted by stargazer2 on July 17, 2007, at 7:46:31
In reply to Re: Info on NMS/Haldol/Phillipa. » stargazer2, posted by Phillipa on July 16, 2007, at 21:39:48
Not sure if it was classified as a tranquilizer in the past, perhaps it was before the AP's became fashionable, but both my 1995 and current drug book classify it as a AP. Rarely is it given anymore with all the atypicals out there. I never gave it in the last 5 years, although they gave it to my father within that time for agitation that was related to being in the ER and having his parkinson's meds not working. Once we got there he became calmer and did not need anything for agitation but can you imagine being in your late 70's, in the ER where he was hallucinating from dopamine imbalence and poor vision and have no one to stay with you? He was on a gurney lined up just waiting for a bed while the other docs and nurses attended to the trauma and victims of violence. It was a way to just shut him up that night.
Stargazer
Posted by Jeroen on July 17, 2007, at 10:34:44
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 17, 2007, at 7:46:31
i heared a woman saying life ends at 14 and starts at 45
because she took lamictal
can you beleive that?
what the zzck iz going on??
Posted by Jeroen on July 17, 2007, at 14:34:28
In reply to strange things in life..., posted by Jeroen on July 17, 2007, at 10:34:44
why did this med destroys my life and my summer again?
is this lamictal induced psychosis, or something?
i'm on abilify they gave it here..
Posted by gardenergirl on July 17, 2007, at 15:36:42
In reply to Re: strange things in life..., posted by Jeroen on July 17, 2007, at 14:34:28
I'm sorry you're still suffering. I'm surprised that such a low dose of Lamictal could have such a serious effect. Did your doctor confirm to you that it was indeed an adverse reaction to Lamictal that caused what you've been experiencing?
Hope you start feeling better very soon,
gg
Posted by Zyprexa on July 17, 2007, at 15:44:06
In reply to Re: strange things in life..., posted by Jeroen on July 17, 2007, at 14:34:28
Posted by Fivefires on July 17, 2007, at 15:55:58
In reply to strange things in life..., posted by Jeroen on July 17, 2007, at 10:34:44
I think medications taken by a person w/ a clean body (This is my not-so-clever wording for a body never having dealt w/ the introduction of a psychiatric medication.) or a person who is younger versus older (There would be vast differences.) are a couple simple reasons, out of very many reasons, medications work so completely different in people.
No two of us are exactly alike, well, not yet anyway.
Life isn't fair.
I wanted to give up last night! Today, I find those thoughts again wondering into my mind. I ask myself, when is this long shitt* haul gonna' end, and what did I do to deserve this?
A good person said have faith your time will come.
Try to dismiss this woman from your thoughts as this is not conducive to you feeling well!
We're here for you. And, I hope your Pdoc is as well.
I hope you feel better soon.
5f
Posted by Phillipa on July 17, 2007, at 19:46:30
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 17, 2007, at 7:46:31
Stargazer no you're right for some reason I was thinking of thorazine. Sorry about that. Yes it is a strong ap. Love Phillipa
Posted by Jeroen on July 18, 2007, at 8:45:39
In reply to Re: hows the abilify? (nm) » Jeroen, posted by Zyprexa on July 17, 2007, at 15:44:06
making me wanna switch too Zyprexa, (even if it doesnt work for my other psychosis) but for lamictal induced whatever...
sigh
Posted by Fivefires on July 18, 2007, at 11:19:23
In reply to To Zyprexa, posted by Jeroen on July 18, 2007, at 8:45:39
Jeroen ... has no one yet shared w/ you that Lamictal did not work for them?
I apologize if asking you, whether or not you have ever had any psychotic episodes (not medication induced) and whether or not you have ever been consistently bipolar are 'too personal' questions to ask.(?)
I have anxiety and depression, never psychoses and never a consistent indication of being bipolar. Lamictal did not work for me, period. I had no change in mood and only got a side order of headache.
I usually don't like to share my experience of a drug w/ someone trying the same drug because POS might interfere, but how many days now have you been on Lamictal?
Do you need some others to jump in here w/ you on this? Try posting differently maybe? Are you getting enough support from people where you are?
5f
Posted by Jeroen on July 18, 2007, at 11:24:25
In reply to Re: To Zyprexa, posted by Fivefires on July 18, 2007, at 11:19:23
not even a week and first day, i was much better
then nightmare, agression, i even threw my playstation 1 down the stairs,
the cops came to rescue ok?
Posted by Fivefires on July 18, 2007, at 11:43:20
In reply to not even a week, posted by Jeroen on July 18, 2007, at 11:24:25
I've had similar first day wonders and then 'poof' .. they're gone!! Always think of the movie, Awakenings!
I don't know what's up w/ this Jeroen, but it su*ks and I'm sorry you're suffering so much.
bestwishes, 5f
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.