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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 25 of 35. This is the beginning of the thread.
Posted by Jeroen on July 14, 2007, at 3:48:42
hi, i am hospitalized for several weeks hoping the fevers stop but
docs do not find anything in my blood so now they are doing other investigationsi am having flu alike fever attacks every day since 4 weeks, of only 1 week taking lamictal
i'm still exausted....
strange things, and doctors dont know, and now are investigating for infection in my body
this is so fustrating, i do am in a emergency med ward, of just trying the med www.lamictal.com25 mg
i'm on abilify, tranxenen, but it just wont passi don't know what 2 do ....
maybe those meds make it worse, i still feel lamictal after 4 weeks in my brain
i propably have a psychosis induced too, no idea
damn,these really are dark ages...
Posted by KayeBaby on July 14, 2007, at 10:48:10
In reply to Lamictal, fever syndrome, unknown psychosis????, posted by Jeroen on July 14, 2007, at 3:48:42
> hi, i am hospitalized for several weeks hoping the fevers stop but
> docs do not find anything in my blood so now they are doing other investigations
>Have they ruled out Neurolectic Malignant Syndrome? What about discontinuing Abilify to see if it my be causing this.
How are your kidneys?
> i am having flu alike fever attacks every day since 4 weeks, of only 1 week taking lamictal
>
> i'm still exausted....
>
>
> strange things, and doctors dont know, and now are investigating for infection in my body
>
>
> this is so fustrating, i do am in a emergency med ward, of just trying the med www.lamictal.com
>
> 25 mg
>
>
> i'm on abilify, tranxenen, but it just wont pass
>
> i don't know what 2 do ....
>
> maybe those meds make it worse, i still feel lamictal after 4 weeks in my brain
>
>
> i propably have a psychosis induced too, no idea
> damn,
>
> these really are dark ages...
Keep talking to us, Jeron.
Ask your Dr.s if you could go off of Abilify and see if it helps. You can always re-start it later.Hang in there.
Kaye
Posted by Phillipa on July 14, 2007, at 11:50:07
In reply to Re: Lamictal, fever syndrome, unknown psychosis????, posted by KayeBaby on July 14, 2007, at 10:48:10
Kaye I never thought of that you could be right. Jeroen does you doc know all the meds you've been on? Love Phillipa
Posted by Jeroen on July 14, 2007, at 12:45:53
In reply to Re: Lamictal, fever syndrome, unknown psychosis???? » KayeBaby, posted by Phillipa on July 14, 2007, at 11:50:07
yhea, ive been thinking bout NMS
but i am on tranxene too because i think i had seizures of quitingbtw how to cure NMS? fever thing, ... if i have it
start Zyprexa ,??????
Posted by KayeBaby on July 14, 2007, at 14:58:02
In reply to neuroleptic magniulan syndrome, posted by Jeroen on July 14, 2007, at 12:45:53
Jeron,
Have your Dr's mentioned this as a possibility?Ask them. Ask them about stopping abilify temporarily.
I think if you have NMS the first thing is to stop any med that could be causing it.
A four week fever with no infection to be found is reason to think about meds causing it.
Talk to the Dr.s.
Do you have anyone that can help advocate for you?
Take Care,
Kaye
Posted by Jeroen on July 14, 2007, at 15:29:46
In reply to Re: neuroleptic magniulan syndrome, posted by KayeBaby on July 14, 2007, at 14:58:02
not from abilify but from LAMICTAL!! ;)
if the NMS is do from Lamictal..
my fever now is 37.3 degrees but it has been higher upto 38 degrees,
it's hard to tell a doctor to stop a med where i am, it's a Belgian Emergency Ward , and they pump up medications to 15 mg of Abilify
i am very upset of what i've done and i hope the lord can forgive me.. i will warn others...
Posted by KayeBaby on July 14, 2007, at 16:25:36
In reply to not from abilify but from LAMICTAL!! ;), posted by Jeroen on July 14, 2007, at 15:29:46
Jeron,
What have you done?I don't know much about this syndrome but just am worried about you.
Take Care,
Kaye
Posted by stargazer2 on July 14, 2007, at 16:42:55
In reply to Re: not from abilify but from LAMICTAL!! ;), posted by KayeBaby on July 14, 2007, at 16:25:36
Here's some info on Neuroleptic Malignant Syndrome...
http://www.cmdg.org/Movement_/drug/Neuroleptic_Malignant_Syndrome/neuroleptic_malignant_syndrome.htm
My father was put into this as a result of the ER at Yale giving him Haldol and he was on Dopamine for parkinsonism. I noted he was febrile and alerted the house staff to this and I commented that I thought he had gone into NMS. They were surprised I knew about this. lUckily it was caught very early and no side effects were long lasting.
Posted by Jeroen on July 14, 2007, at 16:45:01
In reply to Info on NMS (neuroleptic malignant syndrome), posted by stargazer2 on July 14, 2007, at 16:42:55
hey stargazer ... ive read about your story before...
that's why my bell ringed about NMS
seriously...
thanks!
Posted by Phillipa on July 14, 2007, at 18:11:50
In reply to Re: neuroleptic magniulan syndrome, posted by KayeBaby on July 14, 2007, at 14:58:02
Jeroen we've known one another for a long time and I'm begging you to tell your doc whats happening as I agree withe KayeBaby. Love Phillipa
Posted by Jeroen on July 14, 2007, at 19:05:23
In reply to Re: neuroleptic magniulan syndrome » KayeBaby, posted by Phillipa on July 14, 2007, at 18:11:50
sorry dont know what to say nor to do,
ed is aware of my situation, i think bob is too..
thanks for concern, i am in not so good shape
Posted by Phillipa on July 14, 2007, at 22:29:50
In reply to Re: neuroleptic magniulan syndrome, posted by Jeroen on July 14, 2007, at 19:05:23
Well if Ed knows all is okay. Love Phillipa
Posted by stargazer2 on July 15, 2007, at 8:35:13
In reply to stargazer, posted by Jeroen on July 14, 2007, at 16:45:01
Anything that will help you is important to do or say. Do the doctors there mention NMS as the cause of your fever? Do you have rigidity? You have to be very careful with any of the neuroleptics and hopefully you are not on any right now or possibly any antypicals in the future, unless at very low doses. That was one of the known diagnoses I feared when my doctor put me on AP's. I would not go above a certain dosage with abilify.
Good luck with resolving this situation you are in...SG
Posted by Fivefires on July 15, 2007, at 19:31:07
In reply to Info on NMS (neuroleptic malignant syndrome), posted by stargazer2 on July 14, 2007, at 16:42:55
I think this is what happened to my grandmother.
She was given Haldol in an ER.
Once NMS is recognized, is the most important and immediate treatment, the removal of the neuroleptic medication?
And, can that even sometimes 'be too late'?
My grandmother 'never got her mind back'.
She was still energetic and her mind was clear as a bell, the day before.
I apologize if these are questions you cannot answer yourself, but maybe you can, so thanks much.
5f
Posted by Fivefires on July 15, 2007, at 21:16:37
In reply to Info on NMS (neuroleptic malignant syndrome), posted by stargazer2 on July 14, 2007, at 16:42:55
I failed to address my ?s 2 Stargazer by name, so following up her post again, and adding one more question.
I'm so concerned, because, 1) A lot of very ill people were on babble tonight :(, and 2) I've been thinking of trying a low dose atypical antipsychotic for my TRD.
My add'l ? - Could Haldol alone cause neuroleptic malignant syndrome, or more likely the dopamine, or both?
tyshareurknowledge, 5f
ps: I'm now thinking a mood stabilizer may be something safer to ponder.
Posted by Jeroen on July 16, 2007, at 3:58:06
In reply to Re: Info on NMS (neuroleptic malignant syndrome) » stargazer2, posted by Fivefires on July 15, 2007, at 21:16:37
mood stablizer thats what i got it from
lamictal, still having fever
Posted by stargazer2 on July 16, 2007, at 5:44:07
In reply to Re: Info on NMS (neuroleptic malignant syndrome) » stargazer2, posted by Fivefires on July 15, 2007, at 21:16:37
5f, the combination of haldol and sinemet were the cause of my father's NMS. He was given haldol, which prevents dopamine release and sinemet, which promotes dopamine release (since that chemical is soo low in Parkinsonism) and the removal of the much needed dopamine precipitated the syndrome. It was known he was on Sinemet, so it was a medical error to give him Haldol and this was done at Yale, a top 10 hospital in the country. If it was missed there, it would be missed most places unless someone had personal experience with it.
So much is NOT known about how the AP work and in combination with the various other drugs so many of us take, it can be a recipe for disaster. Even my own doctor prescribes AP without thinking about the side effects of NMS.
Removal of the drug, typically an antipsycotic, is the first order of business, followed by the administration of bromcristine and another drug (listed in the article under my post above describing the syndrome and the treatment).
Using an AP on it's own can cause NMS and I think the article said only 0.5-1% develop and 90% develop it within the first two weeks of use. My fear is that no one knows much about it, look at Jereon, and so many others where it is missed routinely.
I took Abilify, Risperdal, Seroquel and zyprexa myself for TRD and try to never do this unless I'm in a real crisis, so I avoid them if at all possible due to the risk, even minor, of NMS.
They have never done much for me in terms of depression resolution. I just stopped abilify on my own due to ineffectiveness, although I'm sure my pdoc would have been happy to see me continue to increase the Abilify rather than the wellbutrin or nardil, I'm not sure why with the seriousness of the side effects.Are the drug companies offering the docs incentives to prescribe the AP's since abify costs $600 for a month's supply and did nadda for me?
Remember, a fever is the classic sign of the syndrome, so an unexplained fever with rigidity is what will usually occur first.
SG2
Posted by Jeroen on July 16, 2007, at 8:33:17
In reply to Re: Info on NMS /5f, posted by stargazer2 on July 16, 2007, at 5:44:07
this is bad, very bad, even the geodon
Posted by Fivefires on July 16, 2007, at 16:12:11
In reply to Re: Info on NMS /5f, posted by stargazer2 on July 16, 2007, at 5:44:07
Tks so much sg2.
I've either overlooked a discussion of NMS b4 now, or was in one and didn't understand the magnitude.
This is a real good reason to say no to APs or mood stabilizers for depression, awa Haldol (a tranquilizer I believe).
No one's gettin' @ my dopamine and that's final!
Maybe I'm already depriving myself of some by taking Xanax, but it's either this or Valium 4me at this time.
My anxiety is my mental illness.
This is a print - author unknown.
Glad you were there for your father.
All my best to Jereon.
YouToo, 5f
Posted by Phillipa on July 16, 2007, at 19:18:19
In reply to Re: Info on NMS. » stargazer2, posted by Fivefires on July 16, 2007, at 16:12:11
Haldol is a major tranquilzer and can also cause TD. I don't think a mood stabalizer such as lamictal, tegretol, depakote,lithium could cause NLS. Love Phillipa
Posted by Fivefires on July 16, 2007, at 20:16:41
In reply to Re: Info on NMS. » Fivefires, posted by Phillipa on July 16, 2007, at 19:18:19
Yeah Phillipa?
I thought someone had posted a mood stabilizer had precipitated NMS, though I could very well be wrong. I'm upset about a life situation here today. I think there were two threads going at the same time on pb yesterday re: NMS.
I'm full of ?s and searching for answers.
Feeling very med skiddish today.
tks, 5f
Posted by stargazer2 on July 16, 2007, at 21:04:10
In reply to Re: Info on NMS. » Fivefires, posted by Phillipa on July 16, 2007, at 19:18:19
FYI...Haldol is classified as an antipsychotic, not a major or minor tranquilizer...SG
Posted by Phillipa on July 16, 2007, at 21:26:33
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 16, 2007, at 21:04:10
SG2 I know it's a typical antipsychotic but didn't they used to classify it as a major tranquiller in the past? Love Phillipa ps we used to give haldol and ativan to out of control patients they stopped the haldol as BP could get so low. Love Phillipa
Posted by Phillipa on July 16, 2007, at 21:39:48
In reply to Re: Info on NMS/Haldol/Phillipa., posted by stargazer2 on July 16, 2007, at 21:04:10
SG2 also used for intracctable hiccups. And mania until the mood stabalizer particularily lithium kicks in. Love Phillipa
Posted by stargazer2 on July 17, 2007, at 7:46:31
In reply to Re: Info on NMS/Haldol/Phillipa. » stargazer2, posted by Phillipa on July 16, 2007, at 21:39:48
Not sure if it was classified as a tranquilizer in the past, perhaps it was before the AP's became fashionable, but both my 1995 and current drug book classify it as a AP. Rarely is it given anymore with all the atypicals out there. I never gave it in the last 5 years, although they gave it to my father within that time for agitation that was related to being in the ER and having his parkinson's meds not working. Once we got there he became calmer and did not need anything for agitation but can you imagine being in your late 70's, in the ER where he was hallucinating from dopamine imbalence and poor vision and have no one to stay with you? He was on a gurney lined up just waiting for a bed while the other docs and nurses attended to the trauma and victims of violence. It was a way to just shut him up that night.
Stargazer
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