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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by willyee on May 9, 2006, at 10:19:00
Kinda weird i ask this since i with all modesty know a hella lot about this drug,but u never know who knows more,so does anyone,ED perhaps no of any medication that might work in synergy with xyrem,xyrem is great for social anxiety but its lack of any stimulant properties makes it very hard to manage without getting foggy headed.
Posted by SLS on May 9, 2006, at 11:26:31
In reply to Xyrem, posted by willyee on May 9, 2006, at 10:19:00
> Kinda weird i ask this since i with all modesty know a hella lot about this drug,but u never know who knows more,so does anyone,ED perhaps no of any medication that might work in synergy with xyrem,xyrem is great for social anxiety but its lack of any stimulant properties makes it very hard to manage without getting foggy headed.
Have you considered adding Provigil? It is expensive, but it has the potential to offset any daytime sleepiness and promote clearer thinking. Some people even report that it reduces anxiety, despite its potential to produce it as a side effect.
- Scott
Posted by willyee on May 9, 2006, at 15:15:18
In reply to Re: Xyrem » willyee, posted by SLS on May 9, 2006, at 11:26:31
Yess i have but i dont see myself getting script for it and its very expensive,adfranil i know isnt a instant stimulant but more over time,im thinking some form of instant stimulant like u spoke of modfanil.
Amphet are no good,trouble with xyrem.Parnate at times when its behaving helps a bit.
Posted by jakeman on May 10, 2006, at 20:31:02
In reply to Xyrem, posted by willyee on May 9, 2006, at 10:19:00
willyee,
how's the xyrem working for insomnia? I've got a doctor who may prescribe it but he wants to try everything else first. And now I'm wondering about a xyrem - ensam combination.
warm regards, Jake
Posted by willyee on May 10, 2006, at 22:22:18
In reply to Re: Xyrem » willyee, posted by jakeman on May 10, 2006, at 20:31:02
I dont use it for insomnia,to do so requires a ver high dose of around 4 grams or higher,also xyrem has a half life of 4 hours so it requires two doses u are instructed to set aside to seperate doses.
Xyrem is an EXTREMLY dose dependant drug,doses to treat anxiet depression depending on weight individual response etc,should be approx no more than 1 gram at most.
This is in high contrast to 4 grams at least for sleep,so its a totaly different story.
Xyrem is believed to have a dopamine rebound effect,but personaly after reading its actualy a glutamine rebound affect,very stimulating and agigtating,so its a drug u wanna use carefully.
In all honesty id ise ambien for insomnia before xyrem,the doses of 4 grams and above are simply to high for this drug.But best wishes if u do try it.......i just hope no pray u know the price of it in vivo ur insurance,because without insurance,ur speaking of 300 dollers at least for a single supply,its extremly extremly expensive.I use it sparingly,as its very powerful.Ambien has been great for insomnia,it seems u can augment ambien with tons of stuff from a small peiace of a benzo,to a beta blocker,to over the counter taurine,all these in combo with a partial pieace of ambien work great for me.
My sleep on parnate is finaly ok,now is the depression,anxiety,social avoidant behaviour issues at hand!What fun!
Posted by jakeman on May 11, 2006, at 20:21:13
In reply to Re: Xyrem, posted by willyee on May 10, 2006, at 22:22:18
willyee thanks for the info, it's helpful. My sleep study showed that I was getting 0 short-wave deep sleep. That's why my sleep doctor is considering it. I can't remember the last time I woke in the morning feeling refreshed. And I always wake in the middle of the night and barely get back to sleep, if at all.
warm regards, Jake
> I dont use it for insomnia,to do so requires a ver high dose of around 4 grams or higher,also xyrem has a half life of 4 hours so it requires two doses u are instructed to set aside to seperate doses.
>
> Xyrem is an EXTREMLY dose dependant drug,doses to treat anxiet depression depending on weight individual response etc,should be approx no more than 1 gram at most.
>
> This is in high contrast to 4 grams at least for sleep,so its a totaly different story.
>
> Xyrem is believed to have a dopamine rebound effect,but personaly after reading its actualy a glutamine rebound affect,very stimulating and agigtating,so its a drug u wanna use carefully.
>
>
> In all honesty id ise ambien for insomnia before xyrem,the doses of 4 grams and above are simply to high for this drug.But best wishes if u do try it.......i just hope no pray u know the price of it in vivo ur insurance,because without insurance,ur speaking of 300 dollers at least for a single supply,its extremly extremly expensive.
>
> I use it sparingly,as its very powerful.Ambien has been great for insomnia,it seems u can augment ambien with tons of stuff from a small peiace of a benzo,to a beta blocker,to over the counter taurine,all these in combo with a partial pieace of ambien work great for me.
>
>
> My sleep on parnate is finaly ok,now is the depression,anxiety,social avoidant behaviour issues at hand!What fun!
Posted by willyee on May 12, 2006, at 22:08:15
In reply to Re: Xyrem » willyee, posted by jakeman on May 11, 2006, at 20:21:13
Well like i said its requires two seperate dosings a night,that be made up prior to laying down.
However xyrem is one of the deepest stages of sleep a drug nutrient or whatever it is now a days can give u,so you very well might benifit greatly from it,just watch out the next day because as ghb dwindles from ur body it lands from gaba recptors to glutmaine recptors,which can cause anxiety the next day,this is sometimes confused with witdrawal but its not,this info i speak of can be found by searching xyrem through WIKIPEDIAS definitation.
Posted by jakeman on May 12, 2006, at 23:34:56
In reply to Re: Xyrem » willyee, posted by jakeman on May 11, 2006, at 20:21:13
Thanks for your reply willyee. I'd like to figure out a vitamen regimem that alliviates any rebound effect.
> willyee thanks for the info, it's helpful. My sleep study showed that I was getting 0 short-wave deep sleep. That's why my sleep doctor is considering it. I can't remember the last time I woke in the morning feeling refreshed. And I always wake in the middle of the night and barely get back to sleep, if at all.
>
> warm regards, Jake
>
>
> > I dont use it for insomnia,to do so requires a ver high dose of around 4 grams or higher,also xyrem has a half life of 4 hours so it requires two doses u are instructed to set aside to seperate doses.
> >
> > Xyrem is an EXTREMLY dose dependant drug,doses to treat anxiet depression depending on weight individual response etc,should be approx no more than 1 gram at most.
> >
> > This is in high contrast to 4 grams at least for sleep,so its a totaly different story.
> >
> > Xyrem is believed to have a dopamine rebound effect,but personaly after reading its actualy a glutamine rebound affect,very stimulating and agigtating,so its a drug u wanna use carefully.
> >
> >
> > In all honesty id ise ambien for insomnia before xyrem,the doses of 4 grams and above are simply to high for this drug.But best wishes if u do try it.......i just hope no pray u know the price of it in vivo ur insurance,because without insurance,ur speaking of 300 dollers at least for a single supply,its extremly extremly expensive.
> >
> > I use it sparingly,as its very powerful.Ambien has been great for insomnia,it seems u can augment ambien with tons of stuff from a small peiace of a benzo,to a beta blocker,to over the counter taurine,all these in combo with a partial pieace of ambien work great for me.
> >
> >
> > My sleep on parnate is finaly ok,now is the depression,anxiety,social avoidant behaviour issues at hand!What fun!
>
>
Posted by willyee on May 13, 2006, at 8:47:02
In reply to Re: Xyrem » jakeman, posted by jakeman on May 12, 2006, at 23:34:56
I have tremdonous experiance with it,and even the founders assistant recomends klonopin be used.....personaly i found a klonopin/liquid deprenyl combo to help alleviate morning rebound.
Unfortuantly since gaba doesent cross well,supplemtnal gaba wont help too much,taurine isnt strong enough,ur prob gonna need a benzo and a stimulant liq deprenyl has a wonderful synergy with klonopin
Posted by Declan on May 13, 2006, at 21:51:24
In reply to Re: Xyrem » willyee, posted by jakeman on May 10, 2006, at 20:31:02
Xyrem Emsam combination. I'm impressed.
Posted by jparsell82 on May 14, 2006, at 23:49:10
In reply to Re: Xyrem » jakeman, posted by jakeman on May 12, 2006, at 23:34:56
Maybe high-dose glycine could help that?
> Thanks for your reply willyee. I'd like to figure out a vitamen regimem that alliviates any rebound effect.
>
>
> > willyee thanks for the info, it's helpful. My sleep study showed that I was getting 0 short-wave deep sleep. That's why my sleep doctor is considering it. I can't remember the last time I woke in the morning feeling refreshed. And I always wake in the middle of the night and barely get back to sleep, if at all.
> >
> > warm regards, Jake
> >
> >
> > > I dont use it for insomnia,to do so requires a ver high dose of around 4 grams or higher,also xyrem has a half life of 4 hours so it requires two doses u are instructed to set aside to seperate doses.
> > >
> > > Xyrem is an EXTREMLY dose dependant drug,doses to treat anxiet depression depending on weight individual response etc,should be approx no more than 1 gram at most.
> > >
> > > This is in high contrast to 4 grams at least for sleep,so its a totaly different story.
> > >
> > > Xyrem is believed to have a dopamine rebound effect,but personaly after reading its actualy a glutamine rebound affect,very stimulating and agigtating,so its a drug u wanna use carefully.
> > >
> > >
> > > In all honesty id ise ambien for insomnia before xyrem,the doses of 4 grams and above are simply to high for this drug.But best wishes if u do try it.......i just hope no pray u know the price of it in vivo ur insurance,because without insurance,ur speaking of 300 dollers at least for a single supply,its extremly extremly expensive.
> > >
> > > I use it sparingly,as its very powerful.Ambien has been great for insomnia,it seems u can augment ambien with tons of stuff from a small peiace of a benzo,to a beta blocker,to over the counter taurine,all these in combo with a partial pieace of ambien work great for me.
> > >
> > >
> > > My sleep on parnate is finaly ok,now is the depression,anxiety,social avoidant behaviour issues at hand!What fun!
> >
> >
>
>
Posted by Jakeman on May 15, 2006, at 18:33:01
In reply to Re: Xyrem » jakeman, posted by jparsell82 on May 14, 2006, at 23:49:10
> Maybe high-dose glycine could help that?
>jparsel,
Thanks for the great suggestion. I had not thought of glycine but you may be onto something. I'm going to do some research.
~Jake
Posted by Jakeman on May 15, 2006, at 18:37:55
In reply to Re: Xyrem » jakeman, posted by Declan on May 13, 2006, at 21:51:24
> Xyrem Emsam combination. I'm impressed.
I wonder if that would work? I'd being willing to try it. I wish I had more knowledge of the mechanisms of hormones and neurotransmitters. I've also thought of Emsam and Lyrica, and a benzo at night like Klonipin or Restoril.
~Jake
Posted by Jakeman on May 15, 2006, at 18:43:24
In reply to Re: Xyrem, posted by willyee on May 13, 2006, at 8:47:02
willyee,
Are you still taking Xyrem? My sleep doctor says the major hassle is taking it twice a night. But I'm already waking at 4 am everyday anyway and wake up feeling like sh*t. That's with every sleep drug...lunesta, ambien, sonata, klonipin, etc.~Jake
> I have tremdonous experiance with it,and even the founders assistant recomends klonopin be used.....personaly i found a klonopin/liquid deprenyl combo to help alleviate morning rebound.
This is the end of the thread.
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