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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Questionmark on April 10, 2006, at 2:20:30
Blueberry's post at this link (www.dr-bob.org/babble/books/20050728/msgs/591219.html), mentioned that the book, _The Mood Cure_, states that... well, i'll paste a part he/she wrote.
"There are tons of little details that are fascinating. Just one tiny example, I never knew that the metabolite of serotonin, after it is broken down in the brain, is crucial for mood...and that SSRIs prevent that metabolite from forming. Tons of details like that."
Is this really true?? Does anyone know for sure? The metabolite of serotonin is involved (/CRUcial??) in mood? It does seem totally logical that all SRIs and MAOIs would prevent that metabolite from forming. (What is the metabolite? Is it 5-HAA or something like that?)
So is this true or not, and if so, how exactly is it involved in mood and what are the consequences of reduced 5-HT metabolite formation?
Posted by SLS on April 10, 2006, at 9:22:32
In reply to Metabolite of Serotonin - important in mood?, posted by Questionmark on April 10, 2006, at 2:20:30
> > "There are tons of little details that are fascinating. Just one tiny example, I never knew that the metabolite of serotonin, after it is broken down in the brain, is crucial for mood...and that SSRIs prevent that metabolite from forming. Tons of details like that."
> Is this really true??
I've never hear of this.
I'm also curious to know more about it.
5-HIAA, if I remember properly, is 5-hydroxy indoleacetic acid. I believe this is the primary metabolite that results from the deamination of serotonin by MAO-A.
- Scott
Posted by linkadge on April 10, 2006, at 12:28:02
In reply to Re: Metabolite of Serotonin - important in mood?, posted by SLS on April 10, 2006, at 9:22:32
I think its possible. I know, for instance that PEA is one of the strongest endogenios CNS stimulants but certain PEA metabolites are powerful CNS depressants.
Linkadge
Posted by Questionmark on April 13, 2006, at 21:08:18
In reply to Re: Metabolite of Serotonin - important in mood?, posted by linkadge on April 10, 2006, at 12:28:02
This is the end of the thread.
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