![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by JaclinHyde on February 28, 2006, at 3:59:38
Just read a nice abstract on the use of Marplan that has me wistful for the days using this drug. I know I am on parnate and I know I am a million times better but Marplan is a great middle of the road MAOI. Had to switch due to a doctor going "hey, you are mildly bipolar!" Parnate is the only MAOI that doesn't cause mania (right, that is why I am typing this at 4 a.m., LOL!) Ah hell, for what it is worth here is the abstract...
"An efficacy study of isocarboxazid and placebo in depression, and its relationship to depressive nosology
by
Davidson JR, Giller EL, Zisook S, Overall JE
Department of Psychiatry, Veterans Administration
Medical Center, Durham, NC 27705.
Arch Gen Psychiatry 1988 Feb; 45(2):120-7ABSTRACT
Isocarboxazid and placebo were evaluated in 130 anxious depressives. Drug was superior to placebo on depression, anxiety, interpersonal sensitivity, and global measures, and on symptoms of hostility, anxiety, obsessiveness, and psychological-cognitive components of depression. There were no significant differences between treatment effects on psychomotor and typical vegetative symptoms. Isocarboxazid was more effective than placebo in major, but not in minor, depression. It was significantly more effective in depression classified as endogenous depression or melancholia by various diagnostic criteria. Drug was more effective than placebo in atypical depression with vegetative reversal and in Brief Psychiatric Rating Scale (BPRS)-derived profiles of anxious and hostile depression; there were no drug-placebo differences in atypical depression without vegetative reversal, or in BPRS retarded and agitated/excited depression. Interpersonal sensitivity emerged as an important drug-responsive dimension."::sniff:: pure poetry :-)
JH
Posted by TylerJ on February 28, 2006, at 10:34:02
In reply to Marplan, how I loved thee, posted by JaclinHyde on February 28, 2006, at 3:59:38
For some reason Marplan didn't work for me. Nardil did but with mega side effects. Parnate...now that's my baby..love it! I think after you've been on parnate for awhile it'll even out for ya...you won't be so "manic". They say when it first starts working it has an amphetamine like effect that fades in 1-2 weeks.
For me I'm enjoying the energizing effect..I don't feel "manic" i just feel alive and well. After feeling like dog crap for so long, this feels absolutely WONDERFUL! Have a great day Terri.:) Ty
p.s. How long have you been on Parnate now? Thurs. it'll be 3 wks for me.
Posted by zeugma on February 28, 2006, at 18:06:58
In reply to Marplan, how I loved thee, posted by JaclinHyde on February 28, 2006, at 3:59:38
that was a lyrical abstract... for what it's worth, i have (among many, many other things) severe 'rejection sensitivity,' 'interpersonal sensitivity,' etc., and TCA's, although effective for depression proper, are worthless when it comes to this dimension. this element is treated with clonazepam... do you have any thoughts on how Marplan compares to clonazepam in terms of this dimension? thanks
-z
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.