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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by Gabbix2 on January 8, 2006, at 12:08:49
Overview of research and findings:
http://news.bbc.co.uk/1/hi/health/4569254.stm
Journal full-text version:
http://ajp.psychiatryonline.org/cgi/content/full/163/1/41
Posted by linkadge on January 8, 2006, at 12:36:01
In reply to Antidepressants and Suicide New Study, posted by Gabbix2 on January 8, 2006, at 12:08:49
I think this is a backlash study, done to try and quell the public's fears about a possable connection between the drugs and suicide risk.
I still think that their is a connection, and would need to see more studies of this nature to convince myself otherwise.
It wasn't just one study that made researchers think there might be a connection, so I'd think it would require more studies to show that there is no connection.
Linkadge
Posted by linkadge on January 8, 2006, at 12:39:18
In reply to Antidepressants and Suicide New Study, posted by Gabbix2 on January 8, 2006, at 12:08:49
They also noted that:
"And adolescents were significantly more likely to attempt suicide than adults in their first six months of taking the drugs."
So there may be some reason why teens are more reactive to drug initiation.
Linkadge
Posted by linkadge on January 8, 2006, at 12:42:11
In reply to Antidepressants and Suicide New Study, posted by Gabbix2 on January 8, 2006, at 12:08:49
As well, the fact that U.S. and European researchers have seemed to consistantly reach somewhat different conclusions about the safety of the drugs seems to raise a flag for me.
Linkadge
Posted by Nickengland on January 8, 2006, at 13:05:29
In reply to Re: Antidepressants and Suicide New Study, posted by linkadge on January 8, 2006, at 12:42:11
I think if theres any doubt, then there is no doubt.
I've seen documentrys on TV where people who took SSRI's who previously had no suicide thoughts or attempts, within 2 weeks were dead.
(Sorry to end on that morbid note)
Kind regards
Nick
Posted by iforgotmypassword on January 8, 2006, at 14:42:11
In reply to Re: Antidepressants and Suicide New Study, posted by Nickengland on January 8, 2006, at 13:05:29
i was on an SSRI during every single suicide attempt i ever made. i also had problems with akithisia, not being able to interpret my feelings or behaviour, and constant inescapable feelings of intense urgency. if you were to ask me based on my experience, i think that there would very likely be a connection.
these kind of creepy "studies" kind of explain why i don't trust the medical establishment all that much anymore.
Posted by Nickengland on January 8, 2006, at 15:15:32
In reply to Re: Antidepressants and Suicide New Study, posted by iforgotmypassword on January 8, 2006, at 14:42:11
I also think with this study...
>a US study suggests.
This is exactly what the drug companies in the US want as this can then be used to target a wider area of business and increase drug sales without doubts that could in effect make the drug sales decline.
From what I've read on this board drug presciption cost are $ big business in the US - and big business needs as many unique selling points as possible to increase the sales of a product...
>They say unnecessary concerns over the drugs may mean people with depression are not taking drugs which could benefit them.
Suicide (especially in the young) is a huge concern. If people decline to take the drugs because of this risk, then the drug compnay will not benefit from them.
The thing is as well (i'm no expert) but if you break down these studies, sometimes you can find out there flawed....I'm not suggesting this one is, but you can find possibly a study and real life accounts on this board even that will suggest otherwise.
Its like, I could bring up a study now of a drug from pubmed and say look - it proves itself as an antidepressant...but then if you look at the study in deatil, you could then find that it was funded by the drug company etc and certain other aspects which then make the study not so much as benefit for the patient, but for the actual company..
Didnt Mac donalds say their food was healthy and pretty risk free - then came along supersize me or whatever ther film was called, then they started coming out with the 'healthy' products like carrot sticks etc..
Posted by Nickengland on January 8, 2006, at 15:25:18
In reply to Antidepressants and Suicide New Study, posted by Gabbix2 on January 8, 2006, at 12:08:49
Posted by Berberis on January 8, 2006, at 17:09:46
In reply to Re: Antidepressants and Suicide New Study, posted by iforgotmypassword on January 8, 2006, at 14:42:11
I had the same experience...especially on Paxil. One week into treatment on Paxil I became acutely suicidal. I'm convinced it was caused by Paxil. I did poorly on almost all SSRI's...they made me anxious, irritable and hypomanic -- why I got the diagnosis of Bipolar II.
Posted by Phillipa on January 8, 2006, at 18:57:13
In reply to Re: Antidepressants and Suicide New Study » iforgotmypassword, posted by Berberis on January 8, 2006, at 17:09:46
Are you saying that if you experince these things on an AD that you are bipolar ll? Fondly, Phillipa
Posted by linkadge on January 8, 2006, at 19:35:34
In reply to Re: Antidepressants and Suicide New Study » Berberis, posted by Phillipa on January 8, 2006, at 18:57:13
There seems to be different branches of thought on the subject. Some doctors think that if an antidepressant produces mania/hypomania then you are definately bipolar. Others think that it may need to fit into a different categry.
Some doctors think that mania produced by antidepressants means nothing at all.
For instance. Dr. Manjii (who does extensive work into bipolar disorder and the mechanisms of mood stabalization) said something along the lines of "Given the right circumstances, it seems that almost anyone can have a manic episode"
Linkadge
Posted by Berberis on January 8, 2006, at 20:46:17
In reply to Re: Antidepressants and Suicide New Study » Berberis, posted by Phillipa on January 8, 2006, at 18:57:13
> Are you saying that if you experince these things on an AD that you are bipolar ll? Fondly, Phillipa
My pdoc told me that because SSRI's caused mood instability (severe rapid cycling in my case) that I was most likely atypical bipolar. I've also been labeled Bipolar nos and Bipolar II. The consensus from a hospitalization was Bipolar II.
Posted by Gabbix2 on January 9, 2006, at 10:36:48
In reply to Thanks for posting this :-) (nm) » Gabbix2, posted by Nickengland on January 8, 2006, at 15:25:18
Your welcome.
I didn't even read it. I was just the "delivery girl" for someone who couldn't post it themselves.
FWIW From my own experience, I think there is a connection.
Posted by Laurie Beth on January 9, 2006, at 13:29:27
In reply to Antidepressants and Suicide New Study, posted by Gabbix2 on January 8, 2006, at 12:08:49
Perhaps SSRIs cause suicidal thoughts/behavior in a few people, decrease suicidal thoughts/behavior in a few people, and the net effect is zero or even beneficial. That still doesn't mean that the SSRI didn't cause suicidal thoughts/behavior in a specific person. Which is why monitoring, especially during dose changes, seems to be a good idea.
Posted by law663 on January 10, 2006, at 22:53:11
In reply to Re: Antidepressants and Suicide New Study, posted by Laurie Beth on January 9, 2006, at 13:29:27
From the footnote of the study:
" During the past 3 years, Dr. Simon has received a research grant from Eli Lilly and Co. (manufacturer of fluoxetine) and has received consulting fees for contributions to a patient education program developed by Pfizer Pharmaceuticals (manufacturer of sertraline). Dr. Wang has provided expert testimony regarding paroxetine and risk of suicide. Dr. Savarino and Ms. Operskalski have no relevant financial interests to disclose. Dr. Simon had full access to all data used for this study and had final responsibility for the decision to submit this manuscript. The funder (NIMH) had no role in study design, data collection, data analysis and interpretation, or preparation of this report."
This is the end of the thread.
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