![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by psychopharmaddict on October 5, 2005, at 14:30:01
I had to post this subject, and didnt really know what to name it but, ok here is the synopsis of what im speaking of. I have been taking this combonation of medication for 18months.
I have in the past 6 yrs, tried so many medications, diagnosed with Refractory depression (low mood and anger), Attention Deficite Disorder (limbic Add), social Anxiety, moresoe always used to hybernate. Addicton I struggled with for a few years, though never cocaine or stimulants.I have to say that even though, and I do admit these 3 drugs can be abused, to a certain extent, but I find myself (luckily not abusing them, but dependant.Meaning I cannot stop one day or withdrawls set in.
I feel in my opinion, Like myself, Kept using alcohol and opiate type drugs , and 3 rehabs, meetings, pscyh doctors, 12 medication and maybe 20 percent effectiveness, even clean 1 yr, and was on Zoloft/Remeron, one of the most potent combinations in reference to Seratonin.
Well it didnt take a neurosurgeon to figure out that the problem wasnt serotonin, or even Norepinephrine. Dopamine( a complicated N.T.), was the culprate. From suffering from these problems, and then abusing 3 different drugs , Alcohol, opiates, and GHB, all dopaminergic reward center activators (nucleus accumbens to frontal lobes, well My doctor agreed in giving me a few tests, one ADD , another a rundown on my history to the tea, and what opinons I had.Starting me on suboxone, helped me stop using oxycontin, and also an added bonus, which suboxone is used in refractory depression (psychopharmacology edition 10), but unnapproved at the time, only for office detox. I dont get a high but a slight mood enhancement , and keep my dose low. Sometimes taking a break.
Now Adderall, I feel helped me like I would never believe. I also was truthful to my doctor, and do not abuse it, and lower my dose sometimes for tolerance issues. Klonopin , I take .5mg for any leftover anxiety.
My problem or point is now, I feel Now Im on these meds for life. Now think about it, .5mg of klonopin, 4mg of suboxone ( 24mg is high) and 75mg-90mg of adderall IR, which is high but my bodywieght and tolerance , my doctor had no problem titrating doose.
I know if i even slowely over time stopped these meds, I would definately go back feeling lousy, antisocial, lazy, unfocuses, and very very tempted to use alochol or drugs. SO in the long run , I would rather take 3 medication for 10 yrs than go back to using. The only thing i look foreward to is the new medication in each catagory which may appear , that may be less dependant and work almost as well. But that may be far and fewPSPHsa
Posted by tbone1 on October 5, 2005, at 15:09:41
In reply to Dopamine/Mu Opiate/Gaba Adderall/Suboxone/Gaba, posted by psychopharmaddict on October 5, 2005, at 14:30:01
> I had to post this subject, and didnt really know what to name it but, ok here is the synopsis of what im speaking of. I have been taking this combonation of medication for 18months.
> I have in the past 6 yrs, tried so many medications, diagnosed with Refractory depression (low mood and anger), Attention Deficite Disorder (limbic Add), social Anxiety, moresoe always used to hybernate. Addicton I struggled with for a few years, though never cocaine or stimulants.
>
> I have to say that even though, and I do admit these 3 drugs can be abused, to a certain extent, but I find myself (luckily not abusing them, but dependant.Meaning I cannot stop one day or withdrawls set in.
>
> I feel in my opinion, Like myself, Kept using alcohol and opiate type drugs , and 3 rehabs, meetings, pscyh doctors, 12 medication and maybe 20 percent effectiveness, even clean 1 yr, and was on Zoloft/Remeron, one of the most potent combinations in reference to Seratonin.
>
> Well it didnt take a neurosurgeon to figure out that the problem wasnt serotonin, or even Norepinephrine. Dopamine( a complicated N.T.), was the culprate. From suffering from these problems, and then abusing 3 different drugs , Alcohol, opiates, and GHB, all dopaminergic reward center activators (nucleus accumbens to frontal lobes, well My doctor agreed in giving me a few tests, one ADD , another a rundown on my history to the tea, and what opinons I had.
>
> Starting me on suboxone, helped me stop using oxycontin, and also an added bonus, which suboxone is used in refractory depression (psychopharmacology edition 10), but unnapproved at the time, only for office detox. I dont get a high but a slight mood enhancement , and keep my dose low. Sometimes taking a break.
>
> Now Adderall, I feel helped me like I would never believe. I also was truthful to my doctor, and do not abuse it, and lower my dose sometimes for tolerance issues. Klonopin , I take .5mg for any leftover anxiety.
>
> My problem or point is now, I feel Now Im on these meds for life. Now think about it, .5mg of klonopin, 4mg of suboxone ( 24mg is high) and 75mg-90mg of adderall IR, which is high but my bodywieght and tolerance , my doctor had no problem titrating doose.
>
> I know if i even slowely over time stopped these meds, I would definately go back feeling lousy, antisocial, lazy, unfocuses, and very very tempted to use alochol or drugs. SO in the long run , I would rather take 3 medication for 10 yrs than go back to using. The only thing i look foreward to is the new medication in each catagory which may appear , that may be less dependant and work almost as well. But that may be far and few
>
> PSPHsaAs an recovering addict good luck because sooner or later you will abuse them. once an addict always an addict and it seems to me that you have done some pretty harsh drug. i almost died from ghb and the oxy is like heroin. you should have learned from rehab that its impossible to substitute
Posted by lunesta on October 5, 2005, at 17:13:07
In reply to Re: Dopamine/Mu Opiate/Gaba Adderall/Suboxone/Gaba, posted by tbone1 on October 5, 2005, at 15:09:41
i was fentanyl (which is more like heroin - i mean geez it comes in lollipops and is 80X more owerful than morphine!)
and I have like 5 boxes of Xyrem (GHB) sitting around but I dont use it cause its prescribed for sleep but i just dont like the effects of it.
Yeah these are tough drugs! That is true, if you are an addict you always will have the urge or whtever.
Posted by blueberry on October 5, 2005, at 18:28:21
In reply to Dopamine/Mu Opiate/Gaba Adderall/Suboxone/Gaba, posted by psychopharmaddict on October 5, 2005, at 14:30:01
If you are doing ok with the three meds, I say great. It sounds like you are well aware of your abuse potential and that you are making efforts to avoid that. And it sounds like you are in close touch with your doctors and being honest with them. If that's the case, it might be a fair idea to stay with it and be vigilant in controlling your meds. Don't let them control you. Sounds like a mood stabilizer should be on board too. Lithium or depakote. Both helpful for current or former abusers with mood problems. Just an opinion though.
Posted by tbone1 on October 7, 2005, at 15:47:22
In reply to Re: Dopamine/Mu Opiate/Gaba Adderall/Suboxone/Gaba, posted by blueberry on October 5, 2005, at 18:28:21
By comparison, antidepressant medications (e.g. Wellbutrin) clearly can make bipolar disorder worse. How often, that's controversial; how much protection against this that one gets from a mood stabilizer, that's not clear either; and when to stop an antidepressant if things are going well, that's controversial too. But that they can in many people, at least 20% and perhaps more like 30 or 40%, depending on circumstances -- that's well agreed upon.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.