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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by rjlockhart98 on August 21, 2005, at 10:04:19
I have read absracts that lose dose of Alprazolam has somewhat of stimulating effect, by working on dopamine systems at low doses. Higher doses dont.
Is this why doctor have the bad apple eye on it.
Dexamphetamine directly stimulates dopamine systems. But its been around so long doctors know all, well some, about its reports since the 1940's.
Anyways, is this theory true?
Posted by ed_uk on August 23, 2005, at 1:24:32
In reply to does Xanax stimulate the reward center?, posted by rjlockhart98 on August 21, 2005, at 10:02:41
Hi Matt,
It doesn't stimulate my reward centre ;-)
~ed
Posted by rjlockhart98 on August 23, 2005, at 1:24:32
In reply to Re: does Xanax stimulate the reward center? » rjlockhart98, posted by ed_uk on August 21, 2005, at 12:50:48
you have taken xanax?
Posted by ed_uk on August 23, 2005, at 1:24:32
In reply to Re: does Xanax stimulate the reward center?, posted by rjlockhart98 on August 21, 2005, at 14:22:37
>you have taken xanax?
Yeah, it wasn't that special. I find Valium more effective. Good thing too, it's the only benzo I can get hold of.
~ed
Posted by Phillipa on August 23, 2005, at 1:24:32
In reply to Re: does Xanax stimulate the reward center? » rjlockhart98, posted by ed_uk on August 21, 2005, at 14:57:12
So ED, How did you get the xanax. And it's definitely not special. Fondly, Phillipa
Posted by lostsailor on August 24, 2005, at 5:32:18
In reply to Re: does Xanax stimulate the reward center? » ed_uk, posted by Phillipa on August 21, 2005, at 19:26:53
I have never heard of the low does theory. I take a rather high dose of Xanax 6-8 mg/ day (doc is ok with 10 if used very judicially and only in cases of bad, bad panic...)
My biggest problem with it is it's short half-life. About 6 hours for me and it's XANAX time...--liken it to an Amex card---don't leave home without it.
When panic symptoms are not as severe, I move to valium and love it, because of the super long half-life and a much more relaxed feeling of not having to always worry about having my pills with me at ALL times. Valium is neat...I am written for 20 mg tid, but doc is cool with me taking it in two divided doses of 30 each or just 20...all my call and he gives me "head room" with this two as one extra is ok with him on a bad day... ( really…some days I’ll take 20 mg in the morning and nothing more till late that night or sometimes the next morning.
Klonopin...I can't understand why docs seem to love it so...it does help Panic patients tremendously, but does not do much for the other anxiety related disorders and in some studies, seems to cause depression.
The other alternative, almost a blend of valium and xanax is ativan.... not as long of a life as valium but a bit longer than xanax.... I have a slight bias, though, as although doc will give it to me, but mum takes it and I get that a neat euphoric feeling from it b/c it is so rare that I use it, but doc is not into me mixing benzos, unless we are out and I have forgotten mine or something...
Hope this helps a bit.
~tony
Posted by ed_uk on August 24, 2005, at 14:21:24
In reply to Xanax stimulating the reward center?xanax users, posted by lostsailor on August 24, 2005, at 5:32:18
>Klonopin...I can't understand why docs seem to love it so...
It's the fashion!
~Ed
Posted by lostsailor on August 25, 2005, at 6:25:10
In reply to Re: Xanax stimulating the reward center?xanax users » lostsailor, posted by ed_uk on August 24, 2005, at 14:21:24
Posted by Kon on August 25, 2005, at 11:43:00
In reply to Xanax stimulating the reward center?xanax users, posted by lostsailor on August 24, 2005, at 5:32:18
> Klonopin...I can't understand why docs seem to love it so...it does help Panic patients tremendously, but does not do much for the other anxiety related disorders and in some studies, seems to cause depression.
One reason...at least wrt the most common anxiety disorder (social anxiety disorder), it is the benzo with the most research evidence for efficacy. In fact, based on individual studies, klonopin had the largest mean effect size on SAD of all medications.
Posted by Paulbwell on August 28, 2005, at 23:26:37
In reply to does Xanax stimulate reward center at low doses?, posted by rjlockhart98 on August 21, 2005, at 10:04:19
> I have read absracts that lose dose of Alprazolam has somewhat of stimulating effect, by working on dopamine systems at low doses. Higher doses dont.
>
> Is this why doctor have the bad apple eye on it.
>
> Dexamphetamine directly stimulates dopamine systems. But its been around so long doctors know all, well some, about its reports since the 1940's.
>
> Anyways, is this theory true?
>
>Hi Ya
I have taken Xanax, and it DOES cause initial reward then followed by sedation, then sleppiness feelings-just like Alcohol. I now take Valium and there is no 'Reward' as there CAN BE with Xanax, i can take take it 3x daily or not at all,I'm supposing because of it's VERY long half life of 200 hours-althought it's CNS effects last only a few hours. Valium is FAR more subtle to the sledge hammer of Xanax which CAN-BE europhic when taken. Hard up, Euphoria, sedation then sleepiness, then frazzled nervers-creating a need for another dose-i have read about this MANY times.
Cheers
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