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Dr. Bob is Robert Hsiung, MD,
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Posted by temoigneur on July 6, 2005, at 0:20:14
Ed supplied these links on shock therapy for OCD/ OCD+MDD etc.
Does anyone have any experience with shock therapy for OCD. Can you detail what worked and what didn't in both successful and unsuccessful trials, and if you're OCD symptoms seem to comform to one of the 4 factors, would you state what type of OCD you suffer..
thanks so much
OCD symptom clusters point to novel treatments
17 Jun 2005
The symptoms of obsessive–compulsive disorder (OCD) occur in clusters that are closely correlated with specific psychiatric symptoms, US scientists have discovered, underlying the importance of subtyping for the treatment of and research into this condition.
Phenotypic heterogeneity is an obstacle to understanding the pathophysiology and etiology of neuropsychiatric disorders, say Gregor Hasler, from the National Institute of Mental Health in Bethesda, Maryland, and colleagues.
They add that this is particularly the case for OCD, as the symptoms and potential causes of this condition are diverse. Recent studies have revealed symptom dimensions that appear to have a biological validity that points to the possibility of specific treatments.
The team interviewed 317 OCD patients using the Structured Clinical Interview for DSM-IV. Of these, 169 completed the Yale–Brown Obsessive–Compulsive Scale Symptom Checklist, while 275 were assessed using the Thoughts and Behaviors Inventory. The results were then subjected to factor and cluster analysis.
The findings pointed to a four-factor model of OCD, which was confirmed using cluster analyses. Factor I consisted of aggressive, sexual, religious, and somatic obsessions, along with checking compulsions. Factor II was made up of obsessions with symmetry, along with repeating, counting, and ordering/arranging compulsions, while Factor III consisted of contamination obsessions and cleaning compulsions. Factor IV was made up of hoarding obsessions and compulsions.
Further analysis revealed that Factor I was associated with comorbid depression and dysthymia, as well as anxiety disorders, including generalized anxiety disorder, panic disorder, agoraphobia, social and specific phobia, and substance use disorders.
Factor II was linked to bipolar disorders, panic disorder/agoraphobia, and substance use disorders, while Factor III was associated with eating disorders, including anorexia, bulimia, and binge-eating disorder, and negatively linked to Tourette's syndrome. Factor IV was not associated with a psychiatric disorder.
The team concludes: "This study encourages further research to elucidate the genetic and neurobiological underpinnings of OCD symptom dimensions and the mechanisms of OCD comorbidity."
The research is published in the journal Psychiatry Research.Thanks again,
Ben
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