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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 18 of 18. This is the beginning of the thread.
Posted by TomG on May 3, 2005, at 13:59:04
1)What is your dosage and most importantly your symptoms? Symptoms are a biggy I want to know as much as you want to type about your symtoms.
2)Response time?
3)Are you getting it overseas without r/x or here in the U.S. legitimatly with a scrip. For those that have done both. What is the best quality. Domestic vs. Foreign and Pill vs. Liquid. I was a little disappointed seeing that the place I was going to order mine online the deprenyl was made in Mexico. That can be skeetchy with some meds depending on what they are.
Best combination? L-phenylalanine + deprenyl?
or DLPA + deprenyl?I've read that breaks or "drug hollidays" as they are called here should be considered instead of a continuos dosing. Any truth?
As best you can do it would be great if you could list the first symptoms that begin to diminish when you knew the drug was working.Anxiety?
Calm feeling?
Much Thanks,Tom
Posted by Declan on May 3, 2005, at 17:27:29
In reply to *******Selegiline******* Responders**** Enter Here, posted by TomG on May 3, 2005, at 13:59:04
Some people think that deprenyl citrate is much better than deprenyl hcl. I've taken both and can't say I noticed a lot of difference. The neuroprotective dose is no greater than 2 mg/day, depending on age. I take 1 and 2 mg deprenyl citrate on alternate days. The effect is potentiated by tyrosine, and phenylalanine. My problem is that if I get the dose high enough to be noticeable and helpful in the day, my sleep is disturbed that night. I'd use dl-phenylalanine rather than the l form. Something to do with a favourable effect on endorphins and PEA. One time when I was using 5 or more mg daily I got that PEA falling in love feeling.
Declan
Posted by Sarah T. on May 4, 2005, at 0:16:50
In reply to Re: *******Selegiline******* Responders**** Enter Here, posted by Declan on May 3, 2005, at 17:27:29
Hello, declan,
Can you tell me the difference between deprenyl citrate and deprenyl HCl? Is one the tablet and the other the liquid? Do you know which of those two is in the selegiline patch that so many of us have been waiting for?
Posted by Declan on May 4, 2005, at 16:46:27
In reply to Re: *******Selegiline******* Responders**** Enter Here » Declan, posted by Sarah T. on May 4, 2005, at 0:16:50
Hi Sarah
Deprenyl citrate is the liquid one, 1mg/drop, deprenyl hcl aka selegeline hcl is the tablet sometimes known as Eldepryl. I assume the patch will be the hudrochloride. On that amount of selegeline ( Its meant to give a dose > 10mg/d?), I don't think I'd sleep.
Declan
Posted by Sarah T. on May 4, 2005, at 22:56:17
In reply to Re: *******Selegiline******* Responders**** Enter Here, posted by Declan on May 4, 2005, at 16:46:27
Hi Declan,
Thanks for the information. When -- or if -- the patch is ever available, I hope they make it in lower strengths.
Posted by KaraS on May 5, 2005, at 21:43:05
In reply to Re: *******Selegiline******* Responders**** Enter Here » Declan, posted by Sarah T. on May 4, 2005, at 22:56:17
> Hi Declan,
> Thanks for the information. When -- or if -- the patch is ever available, I hope they make it in lower strengths.
Hi Sarah,I've read that the lowest strength patch is going to be 20 mg. I don't remember where I read that or I'd post the link.
K
Posted by Sarah T. on May 5, 2005, at 23:34:01
In reply to Re: *******Selegiline******* Responders**** Enter Here » Sarah T., posted by KaraS on May 5, 2005, at 21:43:05
Hi, Kara,
Twenty milligrams??!! That's too much, way too much for a starting dose. I don't suppose that cutting it into smaller pieces would help? What is the matter with these drug companies? There are so many meds that are completely off-limits to me because the smallest strength available is still too high.
Posted by KaraS on May 6, 2005, at 5:15:06
In reply to Re: *******Selegiline******* Responders**** Enter Here » KaraS, posted by Sarah T. on May 5, 2005, at 23:34:01
> Hi, Kara,
>
> Twenty milligrams??!! That's too much, way too much for a starting dose. I don't suppose that cutting it into smaller pieces would help? What is the matter with these drug companies? There are so many meds that are completely off-limits to me because the smallest strength available is still too high.
I could be wrong. But if I'm not, they're probably figuring that 10 mg. can be taken without worrying about the diet (so no need for the patch) and therefore they'd start a bit higher than that. I've wondered about cutting it into smaller pieces also. Don't know if that would work. Seems like it should though. I get rashes just from putting band-aids on so I doubt I'd be able to use any patch unfortunately.k
Posted by TomG on May 6, 2005, at 12:05:42
In reply to Re: *******Selegiline******* Responders**** Enter Here » KaraS, posted by Sarah T. on May 5, 2005, at 23:34:01
Possibly because of the method of delivery of the patch the dosage doesn't necessarily correspond to the oral or liquid forms. Just a thought. I really have no info to back that up.
Posted by Sarah T. on May 6, 2005, at 17:16:59
In reply to Re: *******Selegiline******* Responders**** Enter Here » Sarah T., posted by KaraS on May 6, 2005, at 5:15:06
> > > > > > > I could be wrong. But if I'm not, they're probably figuring that 10 mg. can be taken without worrying about the diet (so no need for the patch) and therefore they'd start a bit higher than that. I've wondered about cutting it into smaller pieces also. Don't know if that would work. Seems like it should though. I get rashes just from putting band-aids on so I doubt I'd be able to use any patch unfortunately. k >
>Thanks, Kara. I get rashes from band-aids, too, including the ones that are supposed to be for sensitive skin. Some of the band-aid rashes I've gotten are worse than the wound I was trying to protect with the band-aid!
Posted by KaraS on May 6, 2005, at 18:09:12
In reply to Re: *******Selegiline******* Responders**** Enter Here » KaraS, posted by Sarah T. on May 6, 2005, at 17:16:59
> > > > > > > > I could be wrong. But if I'm not, they're probably figuring that 10 mg. can be taken without worrying about the diet (so no need for the patch) and therefore they'd start a bit higher than that. I've wondered about cutting it into smaller pieces also. Don't know if that would work. Seems like it should though. I get rashes just from putting band-aids on so I doubt I'd be able to use any patch unfortunately. k >
> >
>
> Thanks, Kara. I get rashes from band-aids, too, including the ones that are supposed to be for sensitive skin. Some of the band-aid rashes I've gotten are worse than the wound I was trying to protect with the band-aid!
I wonder if there is any way around that problem? I hate thinking that this is just another option that won't be available to me. I'm sure you understand.K
Posted by Sarah T. on May 6, 2005, at 19:07:01
In reply to Re: *******Selegiline******* Responders**** Enter Here » Sarah T., posted by KaraS on May 6, 2005, at 18:09:12
> > > > > > > > > > I wonder if there is any way around that problem? I hate thinking that this is just another option that won't be available to me. I'm sure you understand. K>
Are you referring to the problem that we have with the adhesive used on band-aids? Perhaps they'll suggest that we put the patch in a different spot on the body every time we start a new one. I've never used a medicine in patch form before, so I really don't know how this problem is managed. I guess we could ask people who've used estrogen patches or Nicotine patches. When I've absolutely had to have a wound covered, I have found Telfa (or is it Tefla) tape to be the least of the evils; however, if I use it long enough, my skin will get irritated from that, too, but at least I can go for a few days with that brand. Perhaps if the Selegiline patch is successful, eventually the manufacturer will make a patch with adhesive for sensitive skin. I wish I could get more information on why the patch has been delayed again. Even my pdoc isn't sure what's going on.
Posted by TomG on May 6, 2005, at 20:06:31
In reply to Re: *******Selegiline******* Responders**** Enter Here » KaraS, posted by Sarah T. on May 6, 2005, at 19:07:01
Hey at least your doctor knows of the drug Selegiline. My doc looked at me funny when I mentioned it. Then in our next meeting he said more data needs to be compiled before Selegiline is used in psychiatry. I kept my mouth closed this time, because I didn't want to embarass him. Can you say "IN THE DARK"?
Posted by Sarah T. on May 6, 2005, at 20:32:23
In reply to Re: *******Selegiline******* Responders**** Enter Here » Sarah T., posted by TomG on May 6, 2005, at 20:06:31
Hi Tom,
Actually, I've come across a few pdocs who never heard of it, and I was pretty upset that they were in the dark. First, selegiline is NOT a new drug. It's been around for at least ten years, and I read about its use in psychiatry ten years ago. I think some doctors don't bother to read their medical journals. Perhaps they are too busy scheduling patients, one right after the other, and would rather rake in the money than keep up with the literature. If they are unable to keep up with all that reading, then they need to stay current by going to as many meetings and seminars as possible.Secondly, when psychiatrists are board certified, their certification states that they are Board Certified in Psychiatry AND Neurology. They are supposed to know Neurology, and Selegiline is a drug used in Parkinson's Disease and some other neurological disorders as well.
Unfortunately, I think many doctors, once they've gone through medical school and residency, feel as if they've "paid their dues," and they don't bother to live up to the trust and responsibility placed in them when they were granted their degrees. It's very sad and very frustrating. There are so few "complete" doctors. I'm still searching, but, quite frankly, I've found more help and more knowledge on this board than I have in any psychiatrist's office.
Posted by KaraS on May 6, 2005, at 23:46:02
In reply to Re: *******Selegiline******* Responders**** Enter Here » TomG, posted by Sarah T. on May 6, 2005, at 20:32:23
You want to talk frustrating? I recently saw a pdoc from a free clinic. She was a nice, caring person but not well informed. I am taking a small dose of a tricyclic right now and she asked me about the side effects because she said she had never prescribed them before. I was flabergasted. She's middle aged too so it was especially surprising. So I told her a little bit about tricyclics. Imagine if I had brought up the selegiline patch or, God forbid, one of the oral MAOIs! Talk about in the dark!I've also learned more from this board and my own research than from any pdoc.
K
Posted by ed_uk on May 7, 2005, at 9:10:43
In reply to Re: *******Selegiline******* Responders**** Enter Here, posted by KaraS on May 6, 2005, at 23:46:02
Hi K!
> I am taking a small dose of a tricyclic right now and she asked me about the side effects because she said she had never prescribed them before.
OMG, that has to be the most disturbing thing I have ever heard!!!
Ed xx
Posted by KaraS on May 7, 2005, at 16:36:24
In reply to Re: *******Selegiline******* Responders**** Enter Here » KaraS, posted by ed_uk on May 7, 2005, at 9:10:43
> Hi K!
>
> > I am taking a small dose of a tricyclic right now and she asked me about the side effects because she said she had never prescribed them before.
>
> OMG, that has to be the most disturbing thing I have ever heard!!!
>
> Ed xx
Thanks, Ed! I got a good laugh from your response. It's so nice to share that with someone who can fully appreciate it!xxxx
Kara
Posted by medhed on May 8, 2005, at 7:41:13
In reply to Re: *******Selegiline******* Responders**** Enter Here » ed_uk, posted by KaraS on May 7, 2005, at 16:36:24
My new pdoc had no idea, she promised she would research. She is against me researching online. MMMM, I wonder why. I am not going to another doc with blind trust!!! I really want to try the Deprenyl/DPLA mix, imagine an AD with positive side effects. I cannot see any reason she would not prescribe this drug for me except closedmindedness. That will mean ANOTHER referal. You know the funny thing is I can get just about any drug I want on my own, the problem is caring for my own brain chemistry is not working out.
Am I getting excited for nothing, because on paper this drug looks promising and I'm hurting.
This is the end of the thread.
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