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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by linkadge on October 1, 2004, at 9:18:42
I am taking zoloft (50) and depakote 125, and clonazepam 1mg
I am really concerned that the shivvering is the beginnings of serotonin syndrome.Linkadge
Posted by Jasmineneroli on October 1, 2004, at 23:30:15
In reply to getting the shivers/chills again., posted by linkadge on October 1, 2004, at 9:18:42
Linkadge:
I got shivers and chills from Moclobemide and I know that lots of people get chills and shivering as an SE of Lexapro. Could it just be a side effect of Zoloft?
Clonazepam has very little serotonin affect, so I doubt that it could boost Zoloft enough to get SS.
But I know nothing about Depakote.
However, keep very careful notes about your symptoms, because we all respond differently, and contact your doctor, if things get worse.
Best of luck.
Jas
Posted by Emme on October 3, 2004, at 10:32:37
In reply to getting the shivers/chills again., posted by linkadge on October 1, 2004, at 9:18:42
Do you feel cold? Hot? I was freezing cold on Celexa. I haven't actually looked, but you might want to do some poking around and see if one of the serotonin receptors is involved in thermoregulation. One of the dopamine receptors is.
Em
> I am taking zoloft (50) and depakote 125, and clonazepam 1mg
>
>
> I am really concerned that the shivvering is the beginnings of serotonin syndrome.
>
> Linkadge
Posted by Emme on October 3, 2004, at 10:54:01
In reply to getting the shivers/chills again., posted by linkadge on October 1, 2004, at 9:18:42
Have you called your doctor yet? Might be a good idea since you can't go on w/ chills and shivering regardless of the cause.
Quick 2-second google search. FWIW, hypothermia develops in mice given serotonin agonists.
http://www.scripps.edu/news/sr/sr2003/mb0340.html
(You are not a mouse, of course.)Also, here's one w/ humans and buspar
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12093604Dunno if these help.
As I understand it, serotonin syndrome causes *elevated* body temp, right?Feel better.
Emme> I am taking zoloft (50) and depakote 125, and clonazepam 1mg
>
>
> I am really concerned that the shivvering is the beginnings of serotonin syndrome.
>
> Linkadge
Posted by linkadge on October 3, 2004, at 12:15:33
In reply to hypothermia in mice » linkadge, posted by Emme on October 3, 2004, at 10:54:01
I know you are right. I've always had the chills when on an SSRI. Actually caffiene helps to warm me up (not just cause its a hot beverage) probably due to dopamine stimulation.
Linkadge
This is the end of the thread.
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