Psycho-Babble Medication Thread 372452

Shown: posts 1 to 9 of 9. This is the beginning of the thread.

 

Is this drug combo SAFE?

Posted by Squiggles on July 30, 2004, at 17:04:12

I would appreciate a reply to this very much
as it has just started; i worry that "tid" on
the lithium may be a mistake;

Is the following drug combo safe:

900 mg lithium
1.0 clonazepam
150 Imipramine

Thanks so much

Squiggles

 

Re: Is this drug combo SAFE?

Posted by SLS on July 30, 2004, at 17:25:14

In reply to Is this drug combo SAFE?, posted by Squiggles on July 30, 2004, at 17:04:12

> I would appreciate a reply to this very much
> as it has just started; i worry that "tid" on
> the lithium may be a mistake;
>
> Is the following drug combo safe:
>
> 900 mg lithium
> 1.0 clonazepam
> 150 Imipramine
>
> Thanks so much
>
> Squiggles
>
>

Hi Squiggles.

The combo is safe. What about the lithium "tid"? Are you supposed to take 900mg three times a day? That would most certainly be a mistake. Most people end up taking between 900-1500mg per day for bipolar disorder. You know that.

Best wishes.


- Scott

 

Is this drug combo SAFE?

Posted by Squiggles on July 30, 2004, at 17:36:54

In reply to Re: Is this drug combo SAFE?, posted by SLS on July 30, 2004, at 17:25:14

Sorry i was unclear -- the "tid" refers
to
300mg lithium per day -- i.e. 900 per day;

What worries me is that 900mg lithium per
day WITH the imipramine dose may be neurotoxic.

Tx

Squiggles

 

Re: Is this drug combo SAFE?

Posted by Sebastian on July 30, 2004, at 18:43:34

In reply to Is this drug combo SAFE?, posted by Squiggles on July 30, 2004, at 17:36:54

Why would your doctor prescribe some thing that was unsafe. Couldn't you tell your doctor if you don't think it will work for you. Or you could try it for a while and see.

 

Re: Is this drug combo SAFE?

Posted by SLS on July 31, 2004, at 6:27:10

In reply to Is this drug combo SAFE?, posted by Squiggles on July 30, 2004, at 17:36:54

> Sorry i was unclear -- the "tid" refers
> to
> 300mg lithium per day -- i.e. 900 per day;
>
> What worries me is that 900mg lithium per
> day WITH the imipramine dose may be neurotoxic.


Maybe Linkadge can comment on this. I have never heard of such a thing. It should be safe.


- Scott

 

tricyclic and benzodiazepine interaction

Posted by Squiggles on July 31, 2004, at 7:18:41

In reply to Re: Is this drug combo SAFE?, posted by SLS on July 31, 2004, at 6:27:10

Thanks for your reassurance; i've been
reading the pharmacological horror stories
for too long; but to be frank i *did* see
a caution for serotonin and meoclonic
danger on drug.com; on the other hand
Pub-Med papers recommend imipramine and
lithium combinations. I just thought that
an adjunct would be something like an
addition of 300mg not the whole 900mg hog.

tx again

Squiggles

p.s. i'll let you know how it goes - this
btw is related to the gastro problem post
a couple of weeks ago from me, where Panda
responded that he/she thought it may be a
liver problem.

 

Re: tricyclic and benzodiazepine interaction

Posted by SLS on July 31, 2004, at 7:28:19

In reply to tricyclic and benzodiazepine interaction, posted by Squiggles on July 31, 2004, at 7:18:41

> Thanks for your reassurance; i've been
> reading the pharmacological horror stories
> for too long; but to be frank i *did* see
> a caution for serotonin and meoclonic
> danger on drug.com; on the other hand
> Pub-Med papers recommend imipramine and
> lithium combinations. I just thought that
> an adjunct would be something like an
> addition of 300mg not the whole 900mg hog.

For unipolar depression, there is some consensus that the dosages used for lithium augmentation be in the range of 300-600mg. If you tolerate the 900mg, I guess that would end up being a time saver and perhaps represent some insurance just in case you have some atypical presentation of bipolar disorder. If it works - God willing - you can adjust the dosage downward.

Good luck, and don't worry.


- Scott

 

Re: Is this drug combo SAFE?

Posted by Wraith on July 31, 2004, at 13:45:12

In reply to Is this drug combo SAFE?, posted by Squiggles on July 30, 2004, at 17:36:54

Squiggles,

I was prescribed a similar concoction after my combination of Nardil and Surmontil popped out. I am now on 1200mg Lithium, 100mg Amitriptyline and 80mg Proponolol. This has by far been the most effective combination I have tried for my treatment resistant unipolar depression.

I wouldn't worry too much about the lithium as regular blood tests are taken to assess where in the therapeutic window. I hope you find the same relief as I am now enjoying.


Regards

Wraith

 

tricyclic and benzodiazepine interaction » Wraith

Posted by Squiggles on July 31, 2004, at 13:49:16

In reply to Re: Is this drug combo SAFE?, posted by Wraith on July 31, 2004, at 13:45:12

> Squiggles,
>
> I was prescribed a similar concoction after my combination of Nardil and Surmontil popped out. I am now on 1200mg Lithium, 100mg Amitriptyline and 80mg Proponolol. This has by far been the most effective combination I have tried for my treatment resistant unipolar depression.
>
> I wouldn't worry too much about the lithium as regular blood tests are taken to assess where in the therapeutic window. I hope you find the same relief as I am now enjoying.
>
>
> Regards
>
> Wraith

Thank you very much Wraith - i am very
optimistic and releaved that these matters
are monitored.

Maybe this will be the successful try
after all. All the best.

Squiggles

This is the end of the thread.

Show another thread

URL of post in thread:

Psycho-Babble Medication | Extras | FAQ

[dr. bob] Dr. Bob is Robert Hsiung, MD, bob@dr-bob.org

Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.