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Dr. Bob is Robert Hsiung, MD,
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Posted by feelingdizzy on June 16, 2003, at 17:16:44
In reply to Reboxetine (Edronax) , posted by Paulk on July 23, 1998, at 19:34:03
Have s.a.d. took prozac for 6 months although no side effects,got depressed again.swapped to reboxetine 12mg-MAJOR SIDE EFFECTS-extreme dry mouth,severe constipation,sweating,hot flushing to body and face+just recently dizziness headaches and spaced out drunk feeling.I feel ghastly and don't know what to do-all advice/info/tips gratefully received!
Posted by Ynot on July 6, 2003, at 3:52:10
In reply to Re: Reboxetine side effects (Frymet),(heartburn), posted by Caroline76 on January 24, 2001, at 8:32:15
I have been prescribed Reboxitine as of the 3/7/2003. I am male and 38 years of age. This is in conjunction with a maximum dose of seroxat (50mg). After reading all the threads, I have decided to keep a day by day account of my useage of reboxatine, and will post it on this notice board if thats ok.This might help others who are new to this drug.
day 1 : one dose of 4mg taken in conjunction with seroxat 50mg.
effects: at the start i noticed a "discomfort" with urinating. i call it the "dribble" effect.Beware new users of making sure all urine has passed out of the urethra before zipping up, as I found it could lead to errmm wet marks on trousers. Exciteability - I was more excited and agitated (in a good way). Sexual activities :I found on trying to have sex that a feeling of erectile dysfunction was present, but perserverance paid off.A BIG thing i noticed was at the point of climax, the effect of climaxing was much more heightened, to the point of ecstatic. But I also noticed that whereas a male climaxes with sperm ejaculation combined with a feeling of euphoria, my sperm was released roughly three to five seconds prior to feeling of euphoria.This resulted in a "delayed" and "longer" feeling of euphoria. A second attempt at sex two days later produced exactly the same response.
Dry Mouth:this is a very unpleasant side effect I have with reboxetine, but one I can live with.
Sweating: I also had profuse sweating.
Insomnia: no problems with insomnia
General feelings after one weeks use : Reboxetine combined with Seroxat has definitely made me feel "perky". I can feel a marked difference in how I feel and how I approach people. I feel that I "want" to do more.
I will keep you updated with the results of week two.
Please remember: All medication is provided by a practicing GP and a Psychiatrist who work in conjuntion with each other to facillitate a drug programme suitable to MY needs. I strongly suggest that you discuss your research with your GP and seek his / her advice. I do not recommend or condone the use of drugs outside your medical GP's plan for your rehabillitation. Furthermore, my explanations here are related to me only and may not have the same effect for you. It is probable that without medical advice, the taking of any drug without medical advice could lead to adverse effects and I do not recommend you do this. I cannot be held responsible for your health because of reading my postings.
regards
Tony
ps:My last paragraph sounds like a real dampner on things, but I understand what lengths depressed people may go to to try and get "better". I know I have been there too.
Posted by mkdrma on July 24, 2003, at 21:47:36
In reply to Re: Reboxetine - new drug prescribed for me, posted by Ynot on July 6, 2003, at 3:52:10
> I have been prescribed Reboxitine as of the 3/7/2003. I am male and 38 years of age. This is in conjunction with a maximum dose of seroxat (50mg). After reading all the threads, I have decided to keep a day by day account of my useage of reboxatine, and will post it on this notice board if thats ok.This might help others who are new to this drug.
> day 1 : one dose of 4mg taken in conjunction with seroxat 50mg.> effects: at the start i noticed a "discomfort" with urinating. i call it the "dribble" effect.Beware new users of making sure all urine has passed out of the urethra before zipping up, as I found it could lead to errmm wet marks on trousers. Exciteability - I was more excited and agitated (in a good way). Sexual activities :I found on trying to have sex that a feeling of erectile dysfunction was present, but perserverance paid off.A BIG thing i noticed was at the point of climax, the effect of climaxing was much more heightened, to the point of ecstatic. But I also noticed that whereas a male climaxes with sperm ejaculation combined with a feeling of euphoria, my sperm was released roughly three to five seconds prior to feeling of euphoria.This resulted in a "delayed" and "longer" feeling of euphoria. A second attempt at sex two days later produced exactly the same response.
> Dry Mouth:this is a very unpleasant side effect I have with reboxetine, but one I can live with.
> Sweating: I also had profuse sweating.
> Insomnia: no problems with insomnia
> General feelings after one weeks use : Reboxetine combined with Seroxat has definitely made me feel "perky". I can feel a marked difference in how I feel and how I approach people. I feel that I "want" to do more.
> I will keep you updated with the results of week two.
> Please remember: All medication is provided by a practicing GP and a Psychiatrist who work in conjuntion with each other to facillitate a drug programme suitable to MY needs. I strongly suggest that you discuss your research with your GP and seek his / her advice. I do not recommend or condone the use of drugs outside your medical GP's plan for your rehabillitation. Furthermore, my explanations here are related to me only and may not have the same effect for you. It is probable that without medical advice, the taking of any drug without medical advice could lead to adverse effects and I do not recommend you do this. I cannot be held responsible for your health because of reading my postings.
> regards
> Tony
> ps:My last paragraph sounds like a real dampner on things, but I understand what lengths depressed people may go to to try and get "better". I know I have been there too.Ynot,
I would love to know how you do on this drug! I've been gathering info on it for a while, don't know anyone who's taking it.I take Effexor XR and recently increased from 150 to 300mg. I don't feel that much better and I'm blowing up like a balloon! 3 more pounds this weekend! I see my doc next week, so I'm hoping to have all the good info I can for her. I've already decreased my dose back to 150. Oh, I take it for anxiety and panic, along with depression.
Thanks!
Posted by SLS on July 27, 2003, at 23:01:07
In reply to Re: Reboxetine - new drug prescribed for me » Ynot, posted by mkdrma on July 24, 2003, at 21:47:36
Hi.
I had a very difficult time with reboxetine. At 4mg, it did nothing. At 8mg, I became much more depressed with lots of anxiety and suicidal ideation. Within 36 hours of discontinuation, this exacerbation of my condition disappeared. I know several other people who had similar experiences. However, I have read a few success stories as well.
- Scott
Posted by rod on July 29, 2003, at 8:54:45
In reply to Re: Reboxetine - new drug prescribed for me, posted by SLS on July 27, 2003, at 23:01:07
Do you know Southpark? Do you also know the little kid, whose parent have a coffee shop and always give him plenty of coffee? This boy is always trembling, screaming sometimes for no reason and sees tiny dwarfs who steel the underpants of other people. Maybe you know this episode.
When I was on Reboxetine for 6 month, some of my "friends" called me under the boys name. haha very funny. But the Reboxetine was the worst med ever for me and I can not exclude it did some permanent harm to me. who knows. I was extremly nervous, anxious and was unable to relax. Just like this boy. It worked well in the first month, but got constantly worse at the following months, and I was too scared to get off, because I thought it would get even more worse without.
Although the doctors in europe treat Reboxetine as the drug for treatment resistant depressives and some doctors call it a miracle drug.good luck
Roland
Posted by lesliekay on July 30, 2003, at 5:11:11
In reply to Re: Reboxetine - new drug prescribed for me, posted by rod on July 29, 2003, at 8:54:45
sounds nasty!!!The crap we put ourselves through!
Posted by allysssa on August 4, 2003, at 5:58:03
In reply to Re: Reboxetine - new drug prescribed for me » Ynot, posted by mkdrma on July 24, 2003, at 21:47:36
thanks ynot for your info and progress on reboxtine. I only heard of the drug today after a visit to my Doctor. I suffer from manic depression and have basically been feeling at odds with life for the last 4 years. (althougth I was first hospitalized 22 years ago when i was 16) Will be tappering off the aropax over 1 week, then 1 week without meds, then i start the reboxetine. I will try and find out a little more about the effects etc, by using this web sight. Thankyou again for your info, allysssa.
Posted by starflower on January 26, 2004, at 9:53:10
In reply to Re: Reboxetine - off aropax, r'xetine in 2/52 » mkdrma, posted by allysssa on August 4, 2003, at 5:58:03
I'm really sensitive to activating a-ds and so far reboxetine seems fine for me. I'm on 4mg in a split dose and have been for a week. Few very slight side effects - slight dry mouth, slight constipation and occasional waking in the night. I do feel much brighter and will stay on this dose unless I feel the effects lessening after another week or so.
I think it's advisable with any med to go really slowly to start with. Docs tend to whack us on therapeutic doses immediately so you end up with a whole host of side effects to deal with when you're at your lowest. In my experience, some of them can be avoided with a gradual taper on, as well as off. Just as I wouldn't advise anyone to stop suddenly, I wouldn't advise anyone to start abruptly either!
Posted by micro on January 27, 2004, at 8:01:27
In reply to Re: Reboxetine - off aropax, r'xetine in 2/52, posted by starflower on January 26, 2004, at 9:53:10
> I'm really sensitive to activating a-ds and so far reboxetine seems fine for me. I'm on 4mg in a split dose and have been for a week. Few very slight side effects - slight dry mouth, slight constipation and occasional waking in the night. I do feel much brighter and will stay on this dose unless I feel the effects lessening after another week or so.
>
> I think it's advisable with any med to go really slowly to start with. Docs tend to whack us on therapeutic doses immediately so you end up with a whole host of side effects to deal with when you're at your lowest. In my experience, some of them can be avoided with a gradual taper on, as well as off. Just as I wouldn't advise anyone to stop suddenly, I wouldn't advise anyone to start abruptly either!Hello, I hope everyone reads the above post! Almost every psychotropic med can be titrated up more gradually than the recommended manufacturers dosing. A word to those on klonopin especially, it can be taken in halves or pill cut into fourths if necessary to help reduce daytime drowsiness. For outpatients, this seems to be a logical means of avoiding work related issues[side effects which interfere with normal functioning]. A skillful psychopharm should understand this, unfortunately many do not!
Request slower titration yourselves if you experience side effects very quickly!!! The se's will occur early in treatment as a norm if they are going to occur, particularly the first 2 weeks, [the way most pdocs and pcp's rx]. BY the book, doesn't always work with psychotropics for a variety of reasons. Exercise also greatly effects pharmacology. Please read " Sports and Exercise Pharmacology" by Stan Reents Pharmd. Published by Human Kinetics for $45. At www.humankinetics.com if you exercise at all. Godd Luck! Micro.
Posted by trishay on March 7, 2004, at 4:51:46
In reply to Reboxetine (Edronax) , posted by Paulk on July 23, 1998, at 19:34:03
Just started on edronax. Had really bad long lasting side effects going off effexor xr. was on 450mg day gradually went down to 75mg per day over 4 weeks. then had exceptionally bad withdrawal that lasted for 10 weeks. Hope edronax works better. Makes you sweat lots. Am very depressed too.
Posted by Sad Panda on March 8, 2004, at 4:44:08
In reply to Re: Reboxetine (Edronax), posted by trishay on March 7, 2004, at 4:51:46
> Just started on edronax. Had really bad long lasting side effects going off effexor xr. was on 450mg day gradually went down to 75mg per day over 4 weeks. then had exceptionally bad withdrawal that lasted for 10 weeks. Hope edronax works better. Makes you sweat lots. Am very depressed too.
>
>Hi There! :)
Please keep us posted on how you go with Edronax. I'm actually thinking about taking it myself on top of Effexor.
Cheers,
Panda.
Posted by Bill LL on March 9, 2004, at 9:17:32
In reply to Re: Reboxetine (Edronax), posted by trishay on March 7, 2004, at 4:51:46
Were you depressed while on Effexor? And if not, why did you go off of it?
> Just started on edronax. Had really bad long lasting side effects going off effexor xr. was on 450mg day gradually went down to 75mg per day over 4 weeks. then had exceptionally bad withdrawal that lasted for 10 weeks. Hope edronax works better. Makes you sweat lots. Am very depressed too.
Posted by trishay on March 10, 2004, at 6:59:23
In reply to Re: Reboxetine (Edronax), posted by Bill LL on March 9, 2004, at 9:17:32
Yes I was getting more and more depressed, and also was doing really stupid things that I have never done in my life before e.g. driving off in my car to who knows where, and driving dangerously, carelessly. Barricading myself into my hospital room ??? Self harming etc. Makes no sense now, and I have no urge to do these things now.
Posted by trishay on March 10, 2004, at 7:04:33
In reply to Re: Reboxetine (Edronax) » trishay, posted by Sad Panda on March 8, 2004, at 4:44:08
I'm no Doctor, but I would not advise taking Reboxetine with Effexor. I took both for 7 days and it was horrendous. Hot sweats, cold sweaty chills, vomiting, diarrhoea, unable to think straight. Maybe this won't happen to you, but it did to me. Have been on just Reboxetine for one week now and am very depressed. My Dr. says give it some more time. Alright for him to say that.
Posted by nudnik on April 4, 2004, at 13:37:38
In reply to Re: Reboxetine (Edronax) » Sad Panda, posted by trishay on March 10, 2004, at 7:04:33
After I read so many discouraging reports on Edronax I would like to summarise my own experience with this AD. I was diagnosed with major depresson about two years ago. I first was given Zoloft which caused really severe side effects, such as extremely increased heart rate, nausea and aggitation (these side effects set in after two days after I took the first dose). Then I was on Noveril for about one year, but the effectiveness decreased. Now I have been taking Edronax for 15 months (8 mg per day). It started to work quite fast and I was symptom free after 6 month of medication. Then I tried to reduce the dose but the first symptoms of depression started to come back. So my psychiatrist and I decided to enhance the daily dose to 8 mg per day and I feel good again.
When I started with Edronax I suffered from excessive sweating for about two weeks, but this effect was completely gone after these two weeks and never returned. The only side effects I have are obstipation and dry mouth, which are uncomfortable, but tolerable. For some time I had also some difficulty to sleep the night through, but when I started to take the second dose at mid day also this nuissance was gone after two or three days.
Edronax has so much enhanced my quality of life and my ability to work that I think it might be at least worth trying, if your doctor recommends so. (Just as a note: I live in Europe where this medication is approved and available)
Posted by trishay on April 5, 2004, at 5:47:58
In reply to Re: Reboxetine (Edronax), posted by nudnik on April 4, 2004, at 13:37:38
Have been on Edronax 4mg and Lovan for two weeks now. Seems to be OK so far.
Posted by Sad Panda on April 5, 2004, at 6:22:53
In reply to Re: Reboxetine (Edronax) » nudnik, posted by trishay on April 5, 2004, at 5:47:58
Hi nudnik & trishay,
Thanks for keeping us posted. :) It is truely appreciated.
Cheers,
Panda.
Posted by soft on June 17, 2004, at 7:43:04
In reply to Re: Reboxetine (Edronax), posted by Sad Panda on April 5, 2004, at 6:22:53
Well - today I started reboxetine 8mg per day - i will keep posting my progress - i hope i dont get all the side effects although i already have anxiety, constipation and sexual dysfunction due to depression so maybe i wont notice
Posted by Sad Panda on June 19, 2004, at 11:37:42
In reply to Re: Reboxetine (Edronax) » Sad Panda, posted by soft on June 17, 2004, at 7:43:04
> Well - today I started reboxetine 8mg per day - i will keep posting my progress - i hope i dont get all the side effects although i already have anxiety, constipation and sexual dysfunction due to depression so maybe i wont notice
>
>Hi Soft,
Keep us posted on how you go, I am also curious to know what it does to your blood pressure.
Cheers,
Panda.
Posted by soft on June 21, 2004, at 4:10:13
In reply to Re: Reboxetine (Edronax) » soft, posted by Sad Panda on June 19, 2004, at 11:37:42
Apart from the first night when it felt like i had taken speed, I am not having any new side effects - constipation I already had so I dont know if its worse or not - and my anxiety levels were already dropping after coming off moclobemide (I was on that last year and it worked for a while but when I went back on it this year it made me really anxious) so its hard to tell whats actually happening
Posted by D-503 on June 21, 2004, at 12:39:40
In reply to Re: Reboxetine (Edronax) » Sad Panda, posted by soft on June 21, 2004, at 4:10:13
I was on 4mg Reboxetine for about from 31st June to 17th June. By this time I had pretty much all the side-effects in the pamphlet. I was feeling more depressed and anxious, so I increased the dose to 8mg and it still didn't help.
Previously I have been on Prothiaden, Aropax (Paxil), Zoloft (for one day, had an allergic reaction), Prozac, Cipramil (Celexa), Effexor, Aurorix (caused bad migraine headaches). So I've pretty much tried all the SSRI's (Except Lexapro and Luvox), 1 TCA, 1 newer MAOI, 2 SNRI's. Worst experiences with Zoloft, Edronax, Effexor and Aurorix. With Prothiaden coming in 5th. Best short-term with Aropax, best long-term Cipramil.
But still, nothing seems to be able to make me motivated, hell, even Cannabis (which I stopped smoking long ago) made me more active than any of this stuff.What else is there? The best stuff for me would be Cannabis without the paranoia and clouded thinking, any chances of making something like that? :-)
Posted by soft on June 23, 2004, at 7:42:08
In reply to Re: Reboxetine (Edronax) » soft, posted by Sad Panda on June 19, 2004, at 11:37:42
Day 7 of 8mg reboxetine - get dizzy if i stand up too quick - still anxious - constipation persists - usual dry mouth - no sign of mood lift - morbid thoughts continue - lost appetite again - reboxetine feels very "chemical" - cant get a peaceful rested sleep and wake up with vague abstract uncomfortable mental images
Posted by Sad Panda on June 23, 2004, at 9:24:46
In reply to Re: Reboxetine (Edronax) » Sad Panda, posted by soft on June 23, 2004, at 7:42:08
> Day 7 of 8mg reboxetine - get dizzy if i stand up too quick - still anxious - constipation persists - usual dry mouth - no sign of mood lift - morbid thoughts continue - lost appetite again - reboxetine feels very "chemical" - cant get a peaceful rested sleep and wake up with vague abstract uncomfortable mental images
>Do you take it in the AM?
Cheers,
Panda.
Posted by soft on June 29, 2004, at 6:54:25
In reply to Re: Reboxetine (Edronax) » soft, posted by Sad Panda on June 23, 2004, at 9:24:46
I take it twice a day - everything is still the same really
Posted by soft on July 22, 2004, at 5:02:31
In reply to Re: Reboxetine (Edronax) » soft, posted by Sad Panda on June 19, 2004, at 11:37:42
Just over a month on reboxetine 4mg twice a day and my mood has lifted - much less anxiety - but this spell of depression has been ongoing since December so maybe its tailing off naturally - theres no way of telling is there?
This is the end of the thread.
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