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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 17 of 17. This is the beginning of the thread.
Posted by whitecat on May 15, 2004, at 8:07:20
Hi all,
is Moclobemide decreases libido and causes inability to orgasm when in large doses, just like SSRIs and other AD? When I first started taking it I was on 300mg a day and felt perfectly: energetic and sooooo horny. I was happy, really. But this dose did nothing to my social phobia. So I asked my doc to increase it. When on 600 mg I returned to be "an old regular me": a bit sleepy and tired all the time and whith rather low sex drive. Now I'm taking 750 and I almost never horny and can't orgasm anymore! I hate it, I don't feel human, but the worst thing is - I'm so disappointed in this grug. I read a lot about moclo, and got an impression it's the best. Now I feel there is nothing left for me, cause to feel human is too important.
I'd like to know if somebody experienced sexual SE when on moclo. Thanks all.
whitecat
Posted by ramsea on May 15, 2004, at 11:13:43
In reply to moclobemide, posted by whitecat on May 15, 2004, at 8:07:20
It is just so totally typical of ADs. Only Wellbutrin seems to maybe add some revving to the sexual motor. Al the others have a tendency to affect it some way, usually dampening some aspect of drive and completion. But please, it's not all that makes you human. Many fine human beings have a low sex drive.
But I know what you mean, we all like to be sexy and attractive unless we're ordained. So maybe you can try a few things. I already told someone about a book that helped me, called The Antidepressant Survival Guide, by Dr Hedaya, and he is very sympathetic about sexual SEs caused by ADs and some possible ways to help rejuvenate. The other thing is to really build up your confidence in other ways, and to think and dress a little sexy (even if alone at home), just trying various ways to keep yourself sexy.
Millions of people have suffered this with ADs and come through--so will you, most of us do. And there's no lasting effect. Also it's possible the effects subside overtime. And I also heard that we're all so unique that Prozac might dampen my sex drive but not yours, whole moclob in high doses might do that to you, but not me. Hope it works out soon.
Posted by whitecat on May 15, 2004, at 16:45:05
In reply to Re: moclobemide » whitecat, posted by ramsea on May 15, 2004, at 11:13:43
> It is just so totally typical of ADs. Only Wellbutrin seems to maybe add some revving to the sexual motor. Al the others have a tendency to affect it some way, usually dampening some aspect of drive and completion. But please, it's not all that makes you human. Many fine human beings have a low sex drive.
>
> But I know what you mean, we all like to be sexy and attractive unless we're ordained. So maybe you can try a few things. I already told someone about a book that helped me, called The Antidepressant Survival Guide, by Dr Hedaya, and he is very sympathetic about sexual SEs caused by ADs and some possible ways to help rejuvenate. The other thing is to really build up your confidence in other ways, and to think and dress a little sexy (even if alone at home), just trying various ways to keep yourself sexy.
>
> Millions of people have suffered this with ADs and come through--so will you, most of us do. And there's no lasting effect. Also it's possible the effects subside overtime. And I also heard that we're all so unique that Prozac might dampen my sex drive but not yours, whole moclob in high doses might do that to you, but not me. Hope it works out soon.
Thank you very much for your empathy and advices. I'll try to find the book; still I don't think dressing sexy will help me: if I feel sexy I feel sexy no matter what I'm wearing, and if not.... Anyway, thanks a lot. Did you try moclo?
I asked my doc about Wellbutrin, and she said that when it's prescribed here at all it's
only as a drug for thouse why want to quit smoking. :(
whitecat
Posted by nephron on May 16, 2004, at 1:09:39
In reply to Re: moclobemide » ramsea, posted by whitecat on May 15, 2004, at 16:45:05
Are you from Australia? I had a friend who convinced her friends to "give up smoking" to get buproprion/wellbutrin :P
Moclobemide hasn't worked for anyone I've known.
What drugs have you tried?
Posted by cubbybear on May 16, 2004, at 2:04:36
In reply to Re: moclobemide » whitecat, posted by ramsea on May 15, 2004, at 11:13:43
> It is just so totally typical of ADs. Only Wellbutrin seems to maybe add some revving to the sexual motor. Al the others have a tendency to affect it some way, usually dampening some aspect of drive and completion.
That's not true; you shouldn't make blanket statements about "all" ADs. While interference with sexual functioning is very common with the SSRIs, I believe it is much less so with the MAOIs, and other posters can let you know about sex drive/performance with the TCA class of anti-depressants.
As for Moclobemide, I tried it once. I experienced no side effects at all, sexual or otherwise; but at the same time, it only made my depression worse. If you've given this AD about 4-6 weeks' trial and don't see any improvement, then get off it as soon as possible, after a suitable tapering of dose.
Posted by ramsea on May 16, 2004, at 3:32:34
In reply to Re: moclobemide » ramsea, posted by whitecat on May 15, 2004, at 16:45:05
I did try moclob for about a year. I told someone else on this board, it isn't stuck in my mind (have tried LOTS of meds in my time fighting bipolar). That means it didn't do much for my depression and social phobia, but it also didn't cause bad Ses. SSRIs always cause insomnia, agitation/euphoria evenutally mania. But not moclob. I thought since I had successfully self-medicated with Seleginine, which is similar, it would work but didn't. And the Seleg pooped out after two years of real help. I also tried Wellbutrin and it stumulated nasty irritable agitated hypomania. I'm a bit hard to medicate with ease.
Posted by ramsea on May 16, 2004, at 3:53:09
In reply to Re: moclobemide, posted by cubbybear on May 16, 2004, at 2:04:36
I said a tendency-----not that all of them do this always, but that there is a tendency for sexual problems to pop up which are medicine related.
It's very common, and happened to me over the last 30 years on numerous trials of TCA, such as Elavil, imipramine, clopmipramine---my ability to feel sex drive and stay with it was way dampned down., SSRIs like Prozac, Lexapro, Celexa, etc., SNRIs like reboxetine, and some others. I've tried MAOIs, and told the poster it didn't affect my sexuality. Seleginine was a bonus to sex, but it isn't an official anti-depressant. Serzone was okay with sex, but it's been withdrawn so I can;t even suffest it--big black box about liver failure. It's also documented that heavy and prolonged use of benzo can dampen sex drive--not in ALL people, but there's a noted TENDENCY. Drug and alcohol addicts frequently have sex function problems--I learned this when working with addicts for a number of years.
I don't care for being called a liar. My purpose is to share information that I myself have experienced both as a chronic mental health consumer and trained mental health worker. Maybe if you had said it's your experience that what I said is not true, but you respect my right to speak of my own experiences, I wouldn't feel like such a massive stupid idiot now and wondering why I bother to write to people in an effort to share with people like myself struggling to get on in life/
Posted by cubbybear on May 16, 2004, at 4:30:32
In reply to Re: moclobemide » cubbybear, posted by ramsea on May 16, 2004, at 3:53:09
>> I don't care for being called a liar.
I never said that. I said, "That's not true.. . ." Big difference, and if Dr. Bob would look at my post and reply that I wasn't being civil, I will accept that.
Maybe if you had said it's your experience that what I said is not true, but you respect my right to speak of my own experiences,
This is all getting into semantics, and I fully understand how sensitive people can be when they're suffering.
I wouldn't feel like such a massive stupid idiot now and wondering why I bother to write to people in an effort to share with people like myself struggling to get on in life/
Nobody said or even implied anything about your intelligence. Unfortunately, when we join this public forum, there is a risk of feeling upset from other people's postings, even when they mean well. I did not mean to get you feeling bad about yourself.
Posted by whitecat on May 16, 2004, at 14:50:07
In reply to Re: moclobemide, posted by nephron on May 16, 2004, at 1:09:39
> Are you from Australia? I had a friend who convinced her friends to "give up smoking" to get buproprion/wellbutrin :P
>
> Moclobemide hasn't worked for anyone I've known.
>
> What drugs have you tried?
No, I'm not. It seems like me and some australians have the same problem though. :(
I tried Celexa and felt so sick from it - ALL THE TWO MONTHS PERIOD - I don't want to take anything of SSRI family again. It didn't do the job, too. I'm not sure about Moclo: may be it works, may be not, may be just a little..
Posted by bipolarspectrum on May 16, 2004, at 14:59:28
In reply to Re: moclobemide » nephron, posted by whitecat on May 16, 2004, at 14:50:07
Hello,
I'm a fellow moclobemide user who just began 150 mg twice/day... I like it already (for my depression), but I'm so very dizzy!!! Anyone else experience dizziness?? and if so, did it subside with time??
Posted by whitecat on May 16, 2004, at 15:07:56
In reply to Re: moclobemide » ramsea, posted by cubbybear on May 16, 2004, at 4:30:32
people, I appreciate your imputs, all of you, so much, and I don't want you to make war because of my thread (or whatever), we don't need it at all(have enough problems, don't we?)
Feel good, everybody.
> >> I don't care for being called a liar.
>
> I never said that. I said, "That's not true.. . ." Big difference, and if Dr. Bob would look at my post and reply that I wasn't being civil, I will accept that.
>
> Maybe if you had said it's your experience that what I said is not true, but you respect my right to speak of my own experiences,
>
> This is all getting into semantics, and I fully understand how sensitive people can be when they're suffering.
>
> I wouldn't feel like such a massive stupid idiot now and wondering why I bother to write to people in an effort to share with people like myself struggling to get on in life/
>
> Nobody said or even implied anything about your intelligence. Unfortunately, when we join this public forum, there is a risk of feeling upset from other people's postings, even when they mean well. I did not mean to get you feeling bad about yourself.
>
Posted by whitecat on May 16, 2004, at 15:14:28
In reply to Fellow moclobemide user!, posted by bipolarspectrum on May 16, 2004, at 14:59:28
> Hello,
> I'm a fellow moclobemide user who just began 150 mg twice/day... I like it already (for my depression), but I'm so very dizzy!!! Anyone else experience dizziness?? and if so, did it subside with time??
I wasn't dizzy at all. All the SE I felt in the beginning were increased energy and sex drive.
Posted by whitecat on May 16, 2004, at 22:57:19
In reply to Fellow moclobemide user!, posted by bipolarspectrum on May 16, 2004, at 14:59:28
You know, dizziness is stated in my moclo's insert as possible SE. So, everybody is different. Hope it will subside in time.
whitecat
Posted by jasmineneroli on May 20, 2004, at 0:23:34
In reply to moclobemide, posted by whitecat on May 15, 2004, at 8:07:20
Hi:
I agree that Moclobemide can affect libido & orgasms. It happened to me too.
I have recently tapered off moclobemide after an 8 week trial. At 300mg I felt alright, some headache and nausea, but no effect on my GAD + depressive symptoms. At 600mg I had NO libido, NO energy (but less GAD) TERRIBLE headaches and continual nausea. So I lowered the dose, but still had all the side effects, including the lost libido. Even back down to 300mg I had the side effects, but less severe.
I've tried, Remeron, Buspar and Effexor, but the ONLY drug that has helped me, is Klonopin. My psych doesn't really like it (Grrrrrr!) but continues to prescribe it for me. I only take 1mg per day (in 2 doses). I had come off Klonopin prior to trying Moclob. and I believe that worsened my symptoms and caused depression to also happen.
Have your tried Klonopin (Clonazepam)?
Good luck!
Jas
PS I'm waiting for Pregabalin to become available in Canada... I believe it will be the perfect answer! Can you get it where you are?
Posted by whitecat on May 20, 2004, at 15:26:02
In reply to Re: moclobemide » whitecat, posted by jasmineneroli on May 20, 2004, at 0:23:34
> Hi:
> I agree that Moclobemide can affect libido & orgasms. It happened to me too.
> I have recently tapered off moclobemide after an 8 week trial. At 300mg I felt alright, some headache and nausea, but no effect on my GAD + depressive symptoms. At 600mg I had NO libido, NO energy (but less GAD) TERRIBLE headaches and continual nausea. So I lowered the dose, but still had all the side effects, including the lost libido. Even back down to 300mg I had the side effects, but less severe.
> I've tried, Remeron, Buspar and Effexor, but the ONLY drug that has helped me, is Klonopin. My psych doesn't really like it (Grrrrrr!) but continues to prescribe it for me. I only take 1mg per day (in 2 doses). I had come off Klonopin prior to trying Moclob. and I believe that worsened my symptoms and caused depression to also happen.
> Have your tried Klonopin (Clonazepam)?
> Good luck!
> Jas
> PS I'm waiting for Pregabalin to become available in Canada... I believe it will be the perfect answer! Can you get it where you are?
>Hi Jas,
thank you for your post. I asked my doc about Klonopin, and she said it's very sedating. If so, it's not for me, cause I naturally have very little energy. How do you feel on it, are you energetic?
I never heard about Pregabalin, I'll do some research, thank you.
Posted by jasmineneroli on May 20, 2004, at 22:47:07
In reply to Re: moclobemide, posted by whitecat on May 20, 2004, at 15:26:02
Hey there Whitecat:
I was initially prescribed 2mg Klonopin, taken in 2 1mg doses. At first, I did find it slightly sedating, and it affected my energy level. However after about 10 days this effect completely went away. I had absolutely no other side effects on this medication....the only one I've ever tried that didn't give me S.E's that continued.
I'm on a lower dose now...a maintenance level of .5mg x 2 per day ( of my choosing) and feel just great most of the time. When I've added an extra .5 mg, I do feel a bit slow, but not sedated, for the first day or 2.
The sedation is only temporary. Other posters to this site will tell you the same thing (ask Viridis).
In fact, after about 2 weeks I actually began to feel a real mood lift, not just an absence of anxiety.
Hope everything goes well for you.
Jas
Posted by whitecat on May 21, 2004, at 18:25:48
In reply to Re: moclobemide » whitecat, posted by jasmineneroli on May 20, 2004, at 22:47:07
This is the end of the thread.
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