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Dr. Bob is Robert Hsiung, MD,
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Posted by Mike Oxsbig on August 21, 2003, at 14:42:21
In reply to Potential weight gain over time?, posted by Ponder on August 21, 2003, at 12:00:29
I was only on Strat/lex combo for a month and a half, but didn't experience any weight change or diet change. I have been on Lexapro since last October. I've actually lost about 10 lbs since then. I wouldn't worry.
> My physician says that the combination of Stattera and Lexapro is equivalent in its mode of action to Effexor. When Effexor first came out it was touted as a drug that did not cause weight gain, and, in fact, showed some weight loss. As it turns out, the weight loss in the clinical trials is not an accurate reflection of what happens over the long run. Many people have gained significant weight on Effexor.
>
> I see that Strattera is associated with weight loss and Lexapro is supposed to be relatively weight neutral. Am I off-base to be skeptical?
>
> I am bipolar (I or II depending on which evaluation you believe) and got very fat, and later, severely depressed while on a combination of Effexor and Wellbutrin.
>
> Now that I've lost that 50 pounds, I'm nervous about this Stattera/Lex combo that my doctor wants to try.
>
> Any comments will be appreciated. Thanks.
Posted by Kacy on August 21, 2003, at 20:59:41
In reply to Re: Potential weight gain over time?, posted by Mike Oxsbig on August 21, 2003, at 14:42:21
I use Effexor and Straterra. I only use 75 mg of Effexor. I use 100 mg of Straterra.
Even when I went up to 225 mg of Effexor where the NE effects are supposed to have started, I never had the same affect as Straterra, so I think the two drugs are different and am skeptical about the Lexapro/Straterra combo being the equivalent of Effexor.
I started at 40 mg of Straterra for four days and then went to 80 mg for three months. The third month the effects waned some so I went to 100. I didn't have nausea except for the first day. I only had a queasy stomach. (I took it when my stomach was empty.) After a week or so, I could take it on an empty stomach with coffee and have no problems. That's what I do everyday.
I'm having trouble getting over the sedation,though, with the 100 mg. dose. I got over it at the 80 mg. dose. How long has it taken some of you to get over that effect? It is lasting all afternoon. Taking it in the evening brought back some of the anxiety that Straterra decreased, so I don't want to do that. Taking it twice a day didn't help, either.
Posted by bige on August 25, 2003, at 22:04:44
In reply to Re: Response to Lasagna » ben12, posted by Lasagne on August 16, 2003, at 22:57:46
I had been on Ritalin for ten yrs with anxiety developing lately.I heard about Strattera and Mr. Dr. gave me the free samples and set me out on my own. I ahve learned alot in these threee weeks I am currently on 25 and going up to 40 tommorow. I have more clairty and I have lost around 15 pounds. But I feel like I have narcolepsy. I have to sleep for at least 10 min every day in the afternoon or I am zombie like. I stare off into space for minutes for what seems like an eternity. I am entering into my third year of LAw School and I hope that this drug helps my grades but I have to stay awake for class. I am 40 yrs old and 240 lbs it seems like I am not taking nearly enough but I dont want to go up on thedose even through I feel it working. I also take Wellbutrin and Lexapro. How long till these side effects wear off does anyone know?
Posted by Mike Oxsbig on August 26, 2003, at 12:02:06
In reply to Re: Response to Lasagna, posted by bige on August 25, 2003, at 22:04:44
Bige
As noted I started on 40 and went to 80 the first week. I stayed at 80 for a month then went to 120 for a month or so. I was falling asleep for about a week, then the symptoms went away. I am 6'3 and weigh about 220 and am 37. I have gone back to Concerta because the Straterra while not a bad experience did not give me enough benefits over stimulants. I am also working my way off of lexapro. For the last week I have been taking half of a 10mg tablet. So far so good.
Don't know what to tell you other than sharing my experience. The only bad side effects I had were in the sexual department.
Good luck
Posted by Trixie on August 29, 2003, at 14:25:13
In reply to Re: What Strattera dose is too low/high, help.., posted by lessismore on August 21, 2003, at 12:39:29
I started Strattera 40 mg in the AM a week ago and am experiencing a tremendous degree of fatigue. I'm exhausted by noon and if left to my own devices, would sleep for the rest of the afternoon. I am also experiencing insomnia; I can fall asleep if I take an Ambien but as soon it wears off, around 4 am, I cannot get back to sleep.
I can't tolerate this for much longer b/c it is destroying my ability to perform at work.. .I was wondering whether anyone has been able to overcome this side effect through evening or night dosing, and whether anyone has had this side effect resolve in time.
This is my first posting here - I was recently diagnosed with ADD and this is the first ADD med I have tried.
Thanks.
Posted by Lasagne on August 29, 2003, at 14:59:56
In reply to Strattera and fatigue: AM or PM dose?, posted by Trixie on August 29, 2003, at 14:25:13
> I started Strattera 40 mg in the AM a week ago and am experiencing a tremendous degree of fatigue. I'm exhausted by noon and if left to my own devices, would sleep for the rest of the afternoon. I am also experiencing insomnia; I can fall asleep if I take an Ambien but as soon it wears off, around 4 am, I cannot get back to sleep.
>
> I can't tolerate this for much longer b/c it is destroying my ability to perform at work.. .I was wondering whether anyone has been able to overcome this side effect through evening or night dosing, and whether anyone has had this side effect resolve in time.
>
> This is my first posting here - I was recently diagnosed with ADD and this is the first ADD med I have tried.
>
> Thanks.
>Response to above:
Hi: I began the Strattera in the morning and I experienced the same as you are. The doctor advised me to switch to the evening. It helped resolve the daytime sleepiness, but after about a week or so I began having several wakeful periods in the middle of the night. It seems like every two hours I would awaken instead of just sleeping all the way through the night. My doctor then put me on a small dose of Flexeril 10 mgs (a muscle relaxer) at bedtime. That resolved the sleep issues. After about 5-6 weeks on the Strattera most of the obnoxious side effects reduced or completely went away. I can understand your frustration especially if you have to work a full time job. Luckily when I started the Strattera I was a stay at home mom and had flexibility with my schedule. I didn't seem to get much done during the foginess, nausea, lethargic period, but now I do get a lot accomplished and I can go without a nap more often than before my ADD treatment. So all I can say is be patient. If the Ambien doesn't do the trick for you, then you might want to consider a small dose of a muscle relaxer. It really makes a huge difference in how I sleep.
Good luck, Lasagna
Posted by lessismore on August 29, 2003, at 15:14:42
In reply to Strattera and fatigue: AM or PM dose?, posted by Trixie on August 29, 2003, at 14:25:13
I take it at 11:00 or so at night, and I also experience fatigue, but not as much as if I took it in the morning. I am about to start my third week, I'm at 40mg, and have noticed a big improvement. Side effects suck, but it's worth it if I can get organized! And they'll go away.
Posted by manyparts2001 on August 29, 2003, at 16:26:32
In reply to Strattera and fatigue: AM or PM dose?, posted by Trixie on August 29, 2003, at 14:25:13
I never experienced drowsiness with Straterra, but did have wakefulness during the night, so I took an herbal supplement of melatonin which is not habit forming and doesn't leave me feeling drowsy in the morning.
After being on it since April at 80mg/day divided twice/day I finally stopped taking it because of all of the side effects, aggressive behavior, rapid heart beat, profuse sweating and a lot of anger. The benefits were not worth it to me even thoughI was able to concentrate so much better. Oh yes, I also, supplemented with Ritalin 2-3 times /day, and that is what I am on now, with none of the able side effects. Good luck. I hope it works out for you.
Posted by Trixie on August 29, 2003, at 20:19:53
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by manyparts2001 on August 29, 2003, at 16:26:32
Thanks, everyone, for sharing your experiences.
Posted by keffrey on September 1, 2003, at 7:29:01
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by Trixie on August 29, 2003, at 20:19:53
Does anyone have any experience with Wellbutrin and strattera? My 12 year old son has been on Wellbutrin for over a year with pretty good social skills related results. However, Wellbutrin has done nothing for pretty severe attention issues. We are now considering Strattera for those.
Thanks
Posted by bige on September 1, 2003, at 7:36:30
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by Trixie on August 29, 2003, at 20:19:53
In regards to wellbutrin and strattera. I have been on wellbutrin for 2 years along with Ritalin. Worked ok for me but I am 40 yrs old. Just switchedabout a month ago to strattera and Wellbutrin and it works great so far.
Posted by keffrey on September 1, 2003, at 9:55:16
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by bige on September 1, 2003, at 7:36:30
> In regards to wellbutrin and strattera. I have been on wellbutrin for 2 years along with Ritalin. Worked ok for me but I am 40 yrs old. Just switchedabout a month ago to strattera and Wellbutrin and it works great so far.
ThanksHas your doctor mentioned the possibility of eliminating the Wellbutrin?
Posted by bige on September 1, 2003, at 16:33:05
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by keffrey on September 1, 2003, at 9:55:16
No he hasnt mentioned going off Wellbutrin but I also was on Lexapro and I took myself off of that.
Posted by Lasagne on September 2, 2003, at 14:27:56
In reply to Re: strattera and wellbutrin, posted by keffrey on September 1, 2003, at 7:29:01
> Does anyone have any experience with Wellbutrin and strattera? My 12 year old son has been on Wellbutrin for over a year with pretty good social skills related results. However, Wellbutrin has done nothing for pretty severe attention issues. We are now considering Strattera for those.
>
> ThanksReply to above post: We don't have experience with Wellbutrin and Strattera combined, but my son does take Celexa (another antidepressant) with the Strattera. Right now he is having great results on both medications. He is 11 years old and he takes 25 mgs. of Strattera in the a.m. and 50 mgs. of Strattera in the evening along with his Celexa.
My husband takes Wellbutrin and it does have some effect on the impulsiveness of ADD, yet alone it doesn't give enough control so my husband takes Concerta (time release Ritalin) with it. The Wellbutrin mostly helps keep my husband's mood stabilized and the Ritalin helps keep him focused and not so impulsive or hyper.
Good luck!
Lasagna
Posted by utopizen on September 2, 2003, at 19:19:11
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by bige on September 1, 2003, at 16:33:05
Well, when I started on Abilify, I was extremely tired just 20 minutes after taking it, it may as well have been a sleeping pill I was so slowed down, I really had to sleep when I took it. Luckily, I started taking it at night.
A few days later, however, I noticed I could take it in the AM, and that it didn't make me tired at all (it might have even made me less tired). So I think it's always good to try starting for the first week or two on a low-dose in the PM on meds, then if you notice you can still be awake like 2 hours later after taking it, take it in the AM if you want.
My sleep doc suggested Straterra as one of the options for me (I'm a bit tired during the day, and have ADD). Right now I take Desoxyn, but it is annoying to have to take it every 4 hours. I'd like to at least augument it with it if I respond well to it, it's something my doc's had in mind for me to try out for a few months.
But no one here has noticed feeling less tired than they did before after taking Straterra?
Provigil didn't do anything for me, even at 500mg.
Posted by lessismore on September 2, 2003, at 20:27:24
In reply to Re: Strattera and fatigue, posted by utopizen on September 2, 2003, at 19:19:11
Thursday will be three weeks, and I no longer feel tired. I feel more like doing the things I think of. Before I would see things I should do (pick something up, water a plant, make a phone call, whatever) and just not do it. I am a lot more productive now, and I'm sleeping about 7-8 hours a night, w/no naps. lovung it, but prepared for the mood swings that I have heard hit about now. (reading posts from parents w/ ADD kids on Strattera, their kids went wacko at three weeks...off the wall and violent.)
Posted by yeltom on September 2, 2003, at 21:57:11
In reply to Re: strattera WITHDRAWL?, posted by reba on July 30, 2003, at 17:34:27
Thanks for your post.I've been feeling exactly the same way since about two days after I went off of 18 mg of Strattera. I also have been having stomach problems. My shrink said there would be no need to taper, but my opinion is that you should taper off everything. They used to say the same thing about SSRI's. Basically shrinks and drug companies don't know shit. That's one of the reasons this website is so useful. Would be interested in hearing about others who experienced discomfort after discontinuing Strattera. Thanks.
> Ok I was the original one to ask about the withdrawal, so i though I would come back and say more about it to help those who have problems with it in the future.
> Ok, so I looked for ever on the internet about people experiencing strattera withdrawal symptoms and found NOTHING except on the lily website about strattera stating that there was no withdrawal effect.. haha THANKS! so I have been doing a little reasearch on other anti-depressant withdrawal symptoms becuase this is the first kind of med i have taken for anything. My symptoms seem to be alot like other anti-depressant withdrawal symptoms. I did do a little tappereing off; I was originally taking 80mlg, and for a week a went to 40, then after o week on 40 I stopped. I had flu like symptoms such as feeling very tired for no reason, feeling very achy, including very sore muscles, also had bad head aches on and off. I also went through periods of mood swings, like crying over nothing, and having a very short fuse. I aslo seemed to be very sensative to light and sounds. I wasnt hungry and was naushous alot. For me these didnt last that long but long enough... I have been off strattera now for 3 days, and today wok eup feeling a little better. so since messing with my dose ive felt yucky about a week and a half, which isnt so long consedering some of the other things i have read about other anti-depressants! lol. I feel lucky that it is summer and I can allow myself to just lay down and do nothing.. Some of the other things I felt were not being able to wake up for a couple hours after getting out of bed, and also my head feels very weird, almost like i get dizzy, but more like i have soup sloshing around in my head. haha Just very spacy in a bad way i guess. Hopefully this will help some of you! Oh and i was on Strattera for 6 months before going off it. good luck to everyone and thanks for responding!
Posted by reba on September 3, 2003, at 9:39:36
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by bige on September 1, 2003, at 16:33:05
to all experiencing sleepyness at weird times; when i was on strattera i had the same type of thing. i took my dose at night before i went to bed and it seemed to wake me up so i was resless all night. when i got up in the morning i was ok, but then by afternoon i would be dead tired. so i decided that if im awake when i want to sleep and want to sleep while im awake, then maybe taking my dose at the opposite time would do the trick.... so instead of 11:00 pm, id take it at 11:00. this def helped....
the other thing that i realized was that i would be so busy in the morning doing stuff that i wouldnt eat very much at all. and since i never really fest super hungry on strattera i didnt eat when i was supposed to. i realized that not eating at the prober times during the day made my add symptoms worse and i didnt even realize it, i just blamed it on the meds! so my advise is MAKE SURE YOU EAT RIGHT! because you have no idea what kind of effect food can have on you even if you dont feel hungry! changing my diet helped my add symptoms so much, and it seems like such a non important thing! so to everyone having problems, try that before other meds!
Posted by Nachoman on September 18, 2003, at 11:44:46
In reply to Re: strattera WITHDRAWL? (it's real) » reba, posted by yeltom on September 2, 2003, at 21:57:11
I was on Strattera for 2 months at 80mg. I decided to switch back to Adderall because it was having no effect on my ADD symptoms. At the same time that I started back on 40mg Adderall, I completely stopped taking the Strattera. I had no withdrawal symptoms at all.
If it wasn't for the weird and uncomfortable side effects commonly found with Strattera, I would have thought I was taking sugar pills. :)
------ Reply to:
> Thanks for your post.I've been feeling exactly the same way since about two days after I went off of 18 mg of Strattera. I also have been having stomach problems. My shrink said there would be no need to taper, but my opinion is that you should taper off everything. They used to say the same thing about SSRI's. Basically shrinks and drug companies don't know shit. That's one of the reasons this website is so useful. Would be interested in hearing about others who experienced discomfort after discontinuing Strattera. Thanks.
Posted by ready for change on September 18, 2003, at 13:01:22
In reply to Re: Strattera and fatigue, posted by lessismore on September 2, 2003, at 20:27:24
In response to the message below... wow, it is such a "load off," if you will, to see symptoms of other ADDers such as the ones listed here (wanting to do things, but just not doing ANY of them...unless you are going to have something removed from your possesion or something might die - i have to laugh at myself sometimes... the extremes i go through over the most mundane tasks) i have felt so anxious, and stressed over, and guilty thinking i was just lazy. but as i am taking strattera at my own comfort level of increasing dosage ( i don't always listen to the doc - i know my body handles things better with time)and combining it with buspar for the anxiety, i am actually doing things. As my body adjusts to the drug levels and begins to have a constant level, i think i will have more consistant behavior ( sometimes i don't get charged up until 10 at night, and i'll work until 2... but thats better than not sleeping all night stressing over all things i have to do in the morning to make up for what i didn't do that night before i went to bed (all of which i probably wouldn't get done anyways!) ok, i'll stop blabbering... but be patient (WHAT??? how can an ADDer be patient... just try to breathe and as time goes on you will learn patience... i am still trying)and dig deep in your mind and let it all go... and the straterra will start working - we have to relearn all of our old habits too... perfection will never happen! (its ok to make mistakes, that is something i didn't realize kept me from doing alot of things i wanted to do)...any comments from others going through this is very helpful in the growing process... best of luck to ya!
> Thursday will be three weeks, and I no longer feel tired. I feel more like doing the things I think of. Before I would see things I should do (pick something up, water a plant, make a phone call, whatever) and just not do it. I am a lot more productive now, and I'm sleeping about 7-8 hours a night, w/no naps. lovung it, but prepared for the mood swings that I have heard hit about now. (reading posts from parents w/ ADD kids on Strattera, their kids went wacko at three weeks...off the wall and violent.)
Posted by Kacy on September 20, 2003, at 8:11:52
In reply to Re: Strattera and fatigue... patience, posted by ready for change on September 18, 2003, at 13:01:22
My doctor won't augment Strattera with a stimulant and insisted on evening dosing to get rid of the afternoon sedation that just won't end. He believes that eliminates the problem and anything else is all in my head. Well, it did end the problem, but it also eliminated the Strattera. With evening dosing, I don't get any effect during the day.
The drug doesn't last 24 hours at a therapeutic level for me. It lasts about 10 hours. The decline in the evening is easy to track by the return of anxiety. It keeps increasing from late afternoon on. The best thing Strattera has done for me has been to take that away. I don't think I realized how much anxiety I had and how much I must have always had until I began Strattera. Taking away anxiety, alone, helps some with add/inattentive problems. The kicker is killing me, though. I just went back to am dosing and the afternoon sedation is back full force.
I understood more when I saw that the drug's half-life was 5.15 hours. But, that is about the same half-life as Effexor. So, why would Effexor last 24 hours a day while Strattera lasts ten?
Do the rest of you who take it in the evening get the benefit of the drug during the day? Does anyone else experience what I do?
Posted by free wheelen on September 20, 2003, at 8:36:18
In reply to Re: Request Straterra side effects solutions?, posted by readyforchange on August 10, 2003, at 14:09:21
I have lived my life thinking that I was superior to most people. Why? because I able to work at 100 miles an hour for 14+ hours a day for weeks on end until I would crash for a day or two and then I would be right back to it. Because I could multi task,I couldn't figure out why no one else could or wanted to drive down the expressway at 80+ eating lunch,working on their laptop, talking on 2nextells and of course listening to the radio full volume. Because I loved drinking 3 to 4 44oz dietsodas(diet of course)a day along whith a couple of Metabo Life just to get me going, yea maybe I couldn't remember what my customers name was or where I left my pen, glasses,day planner,phone ect. Sound familiar?
Posted by Ritchie on September 20, 2003, at 8:49:37
In reply to Re: Strattera am or pm dose and response, posted by Kacy on September 20, 2003, at 8:11:52
> My doctor won't augment Strattera with a stimulant and insisted on evening dosing to get rid of the afternoon sedation that just won't end. He believes that eliminates the problem and anything else is all in my head. Well, it did end the problem, but it also eliminated the Strattera. With evening dosing, I don't get any effect during the day.
>
> The drug doesn't last 24 hours at a therapeutic level for me. It lasts about 10 hours. The decline in the evening is easy to track by the return of anxiety. It keeps increasing from late afternoon on. The best thing Strattera has done for me has been to take that away. I don't think I realized how much anxiety I had and how much I must have always had until I began Strattera. Taking away anxiety, alone, helps some with add/inattentive problems. The kicker is killing me, though. I just went back to am dosing and the afternoon sedation is back full force.
>
> I understood more when I saw that the drug's half-life was 5.15 hours. But, that is about the same half-life as Effexor. So, why would Effexor last 24 hours a day while Strattera lasts ten?
>
> Do the rest of you who take it in the evening get the benefit of the drug during the day? Does anyone else experience what I do?
I find the best way to get the benefits of Strattera is I take 40 mg in the a.m. and I take 40 mg around 12:30, it works for me. I don't have ADHD or ADD, I take it for depression, suicidal idealtions and anxiety and it works for me. I think the sleepiness will wear off with time as will the dry mouth. All I know is it works for me and it evens me out.
Posted by Kacy on September 20, 2003, at 9:55:55
In reply to Re: Strattera am or pm dose and response, posted by Ritchie on September 20, 2003, at 8:49:37
Thanks, Ritchie. I tried that, too. I took 60 in the morning and 40 after lunch for a while. Then, I took 60 at noon and 40 late afternoon. I ended up reducing my response to the drug and just moving the sedation around to different times.
I'm on my fourth month at 100 mg. I've always heard if the side effects are still there three months later, they're not going to pass. I hope that's not true. The thought of starting over with a new drug is tiring all by itself.
Posted by Kacy on September 20, 2003, at 11:11:48
In reply to Re: Strattera and fatigue: AM or PM dose?, posted by reba on September 3, 2003, at 9:39:36
Your point is excellent, Reba. I have been experimenting with that, too. It seems that eating lunch sets off the tiredness. I'm eating healthy foods, but maybe it's the kind of food. What changes did you make in your diet? Did you make any changes in the times you ate other than making sure you had breakfast?
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