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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 20 of 20. This is the beginning of the thread.
Posted by GreatDaneBoy on August 25, 2003, at 0:17:19
Has anyone heard of this? I came across an article on the net touting its anti-anxiety and antidepressant properties.
Any insight would be greatly appreciated!
Dane =)PS I am taking Depakote (1500 mg), Lamictal (400 mg), Seroquel (800mg), and Prozac (80mg).
Posted by Caleb462 on August 25, 2003, at 0:30:46
In reply to Salvia divinorum, posted by GreatDaneBoy on August 25, 2003, at 0:17:19
> Has anyone heard of this? I came across an article on the net touting its anti-anxiety and antidepressant properties.
>Salvia Divinorum is a plant, that produces extremely intense dissassociative/psychedellic experiences when consumed - particularly when smoked. Its active chemical is a kappa opiod agonist. Kappa agonists are known to induce dysphoria and psychotic-like states. Some people find the experiences with this plant very enlightening and mind-opening, but from what I understand - it can be a very frightening, disturbing experience as well.
If you have mental health issues, it is probably not something you'd want to mess around with.
Posted by Ame Sans Vie on August 25, 2003, at 0:38:03
In reply to Re: Salvia divinorum, posted by Caleb462 on August 25, 2003, at 0:30:46
Not to mention that salvinorin A is likely to soon become a Schedule I substance. And that likelihood is even greater if the government finds out about the new salvinorin A blotter that's being sold -- looks like LSD, acts like LSD... stronger though. And anyone with half a brain in their head can manufacture it in this form using very simple kitchen chemistry.
What a drag... I personally enjoy Sally D every now and then.
Posted by GreatDaneBoy on August 25, 2003, at 0:40:34
In reply to Re: Salvia divinorum, posted by Caleb462 on August 25, 2003, at 0:30:46
Thanks for the advice! I didn't realize that it could cause psychosis...I am already taking a huge dose of Seroquel to keep that at bay as it is. I don't think I'll take the risk.
Thanks again for the advice!
Woof!
Posted by Caleb462 on August 25, 2003, at 0:53:26
In reply to Re: Salvia divinorum, posted by Ame Sans Vie on August 25, 2003, at 0:38:03
> Not to mention that salvinorin A is likely to soon become a Schedule I substance. And that likelihood is even greater if the government finds out about the new salvinorin A blotter that's being sold -- looks like LSD, acts like LSD... stronger though. And anyone with half a brain in their head can manufacture it in this form using very simple kitchen chemistry.
>
> What a drag... I personally enjoy Sally D every now and then.
Acts like LSD? Certainly the pharmacological mechanisms are different... and from what I understand, a salvia trip is WAY different than LSD or any other psychedellic/hallucinogen.I've never done it, though I'm certainly curious. I find plain ol' pot to be fairly psychedellic, and it can freak the beejeezus out of me at times... so I plan to stay away from anything "harder" for the time being.
Posted by Treb on August 25, 2003, at 1:02:24
In reply to Re: Salvia divinorum, posted by Caleb462 on August 25, 2003, at 0:53:26
Hi, I founda Medical Abstract about the Antidepressive use of the plant by one woman:
http://www.erowid.org/references/refs_view.php?A=ShowDoc1&ID=1316
Here is a link to more information about the plant:
http://sagewisdom.org/usersguide.html
Seems like it needs a lot of study for having medicinal uses in our arena! Thanks, Treb
Posted by GreatDaneBoy on August 25, 2003, at 1:06:26
In reply to Re: Salvia divinorum, posted by Treb on August 25, 2003, at 1:02:24
Posted by galkeepinon on August 25, 2003, at 1:47:39
In reply to Salvia divinorum, posted by GreatDaneBoy on August 25, 2003, at 0:17:19
Hi,
This site gives a little info on its antidepressant effects: www.erowid.org/plants/salvia/salvia.shtmland here's a site concerning its legal status:
www.erowid.org/plants/salvia/salvia_law.shtml> Has anyone heard of this? I came across an article on the net touting its anti-anxiety and antidepressant properties.
>
> Any insight would be greatly appreciated!
> Dane =)
>
> PS I am taking Depakote (1500 mg), Lamictal (400 mg), Seroquel (800mg), and Prozac (80mg).
Posted by galkeepinon on August 25, 2003, at 1:50:25
In reply to Salvia divinorum, posted by GreatDaneBoy on August 25, 2003, at 0:17:19
Posted by Ame Sans Vie on August 25, 2003, at 7:08:13
In reply to Re: Salvia divinorum, posted by Caleb462 on August 25, 2003, at 0:53:26
In my experience, a S.D. trip is extremely similar to an acid trip -- just way more intense. All the usual characteristics of the LSD trip are present -- altered thought processes, deep introspection, brightened colors, intense open-eye visuals, and even more intense closed-eye visuals. The only thing really missing is that speedy type of feeling LSD provides... so in that regard, salvia is a bit more like psilocybe mushrooms.
As far as I know, the pharmacolical mechanisms of salvinorum A and LSD are almost identical: while the jury's still out on *exactly* how they operate on these receptors, both drugs affect 5HT1 and 5HT2 primarily. The debate seems kind of funny, though... they can't figure out whether the drugs are agonistic or antagonistic at 5HT2. :-\
Posted by Ame Sans Vie on August 25, 2003, at 7:16:00
In reply to Re: Salvia divinorum » GreatDaneBoy, posted by galkeepinon on August 25, 2003, at 1:47:39
Salvia could be an absolutely wonderful therapeutic tool -- just as LSD and MDMA could have been. This is one of the few true psychedelics that aren't covered in the CSA (so many plants contain DMT or 5-MeO-DMT that it'd be impossible for them to control those plants -- phalaris grass is *everywhere*), and I for one hope it stays that way. I wrote my state representatives recently to raise the issue and ask what their vote will be on the possible future bill to criminalize it. Aside from touting its medical benefits, I'm also playing the religious-freedom-card, lol. I use salvia on every solstice and equinox of the year for vision quests as I'm a pagan High Priest. (I don't want to lie though, from time to time I might indulge in a magic mushroom or two ;-)
Posted by GreatDaneBoy on August 25, 2003, at 11:59:34
In reply to Re: Salvia divinorum » GreatDaneBoy, posted by galkeepinon on August 25, 2003, at 1:47:39
Hi Ames!
Thanks for the info! Do you think that the psychedelic effects would be countered by the Seroquel that I take? I take a big dose--800 mg.
Blessed Be,
Dane =)
"An it harm none do what you will".
The wiccan rede
Posted by BarbaraCat on August 25, 2003, at 13:17:58
In reply to Re: Salvia divinorum, posted by Ame Sans Vie on August 25, 2003, at 7:16:00
I've been looking everywhere for this little sprout. Since it's not yet on any scheduled drug list, would it be available ordering through my local nursery? Internet source? Grown by seed? Am I asking naughty questions?
Blessed Be to Thee and Me,
BarbaraCat
Posted by Caleb462 on August 25, 2003, at 13:19:31
In reply to Re: Salvia divinorum, posted by Ame Sans Vie on August 25, 2003, at 7:08:13
> In my experience, a S.D. trip is extremely similar to an acid trip -- just way more intense. All the usual characteristics of the LSD trip are present -- altered thought processes, deep introspection, brightened colors, intense open-eye visuals, and even more intense closed-eye visuals. The only thing really missing is that speedy type of feeling LSD provides... so in that regard, salvia is a bit more like psilocybe mushrooms.
>
> As far as I know, the pharmacolical mechanisms of salvinorum A and LSD are almost identical: while the jury's still out on *exactly* how they operate on these receptors, both drugs affect 5HT1 and 5HT2 primarily. The debate seems kind of funny, though... they can't figure out whether the drugs are agonistic or antagonistic at 5HT2. :-\You sure about that? From my understanding salvinorin A is a kappa opiod agonist, and has no affinity for 5-HT receptors. I certainly could be wrong...
Posted by Caleb462 on August 25, 2003, at 13:24:35
In reply to Re: Salvia divinorum, posted by Ame Sans Vie on August 25, 2003, at 7:08:13
"We discovered that Salvinorin A potently and selectively inhibited (3)H-bremazocine binding to cloned kappa opioid receptors. Salvinorin A had no significant activity against a battery of 50 receptors, transporters, and ion channels and showed a distinctive profile compared with the prototypic hallucinogen lysergic acid diethylamide. Functional studies demonstrated that Salvinorin A is a potent kappa opioid agonist at cloned kappa opioid receptors expressed in human embryonic kidney-293 cells and at native kappa opioid receptors expressed in guinea pig brain. Importantly, Salvinorin A had no actions at the 5-HT(2A) serotonin receptor, the principal molecular target responsible for the actions of classical hallucinogens"
Posted by Ame Sans Vie on August 25, 2003, at 23:58:08
In reply to Re: Salvia divinorum » Ame Sans Vie, posted by BarbaraCat on August 25, 2003, at 13:17:58
lol, well even though it's not illegal, I don't think Dr. Bob would appreciate anyone using this forum to directly provide that sort of information. You can e-mail me at aedigheduirmott@aol.com if you'd like a link to a site that carries it for a great price. Absolutely nothing sold there is illegal, though the San Pedro cactus *is* a source of mescaline, and both morning glory and Hawaiian baby woodrose seeds are sources of lysergic acid (LSA), a close relative of LSD.
I'd suggest buying either the 5x or 10x salvia -- this means that the plant was treated with the active chemical (salvinorin A) in such a way that, for example, one gram of 5x salvia is equivalent to five grams of untreated salvia. It can either be smoked (in which case a waterpipe should be used and each inhalation held in as long as possible) or extracted and made into "blotter", like LSD. If you'd like to know how to go about doing this, let me know. It's not a terribly complicated task.
Just one thing to keep in mind (though I'm sure you already know this) -- *do not use salvia if you are in any sort of negative state of mind*. It's just like LSD in that regard. Mood and setting are extremely important, and even more so on salvia, since the experience is so much more intense.
Bright blessings,
Michael
Posted by Ame Sans Vie on August 25, 2003, at 23:59:35
In reply to Re: Salvia divinorum, posted by Caleb462 on August 25, 2003, at 13:24:35
Oops! You're right, sorry about that... I suppose I was thinking of some tryptamine psychedelic... probably psilocybin.
Posted by River1924 on August 26, 2003, at 20:31:38
In reply to Re: Salvia divinorum » Caleb462, posted by Ame Sans Vie on August 25, 2003, at 23:59:35
I don't understand the urge to "trip" when most of the people on this board can not get their meds to work. Is "tripping" helpful in some way or is it self-destructive? I personally feel like like my brain is a pressure cooker of legal drugs and enviromental toxins. I guess it is a personal choice.
Posted by stjames on August 26, 2003, at 21:28:29
In reply to Re: Salvia divinorum...why?, posted by River1924 on August 26, 2003, at 20:31:38
> I personally feel like like my brain is a pressure cooker of legal drugs and enviromental toxins.
The blood/brain barrier make sure your brain is
not full of "legal drugs and enviromental toxins". Most meds/toxins don't pass to the brain.
Posted by Caleb462 on August 26, 2003, at 22:08:43
In reply to Re: Salvia divinorum...why?, posted by River1924 on August 26, 2003, at 20:31:38
> I don't understand the urge to "trip" when most of the people on this board can not get their meds to work. Is "tripping" helpful in some way or is it self-destructive? I personally feel like like my brain is a pressure cooker of legal drugs and enviromental toxins. I guess it is a personal choice.
Many people find that "tripping" can be a theraputic tool. Psychedellic trips can be mind-opening, insight-giving experiences for many folks. Me... I freak out even on weed sometimes, so I'm saving my psychedellic experiences for sometime later in life when I feel I am more stable.
This is the end of the thread.
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