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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by borderliner21 on October 21, 2002, at 16:31:34
FOr those people taking zyprexa for depression and anxiety reasons, what dosage worked best for you along with your AD's. I find 3.75 mg works the best for me. 5 mg gives me akathesia.
Posted by Mr Beev on October 21, 2002, at 19:47:40
In reply to zyprexa dose, posted by borderliner21 on October 21, 2002, at 16:31:34
I find that a rather small dose, 2.5mg, taken as needed, rather than regularly, works very well for troublesome agitation. It does not interfere with my AD, Effexor.
The first few doses laid me out cold and greatly stimulated my appetite. Nowadays the only side-effects I notice are (1) occasional mild appetite stimulation, (2) occasional mild headache on arising, which goes away, or responds to ibuprofen, and (3) it is still fairly soporific, so I take it at bedtime.
Regards,
Mr Beev
Posted by chad_3 on October 21, 2002, at 22:57:01
In reply to zyprexa dose, posted by borderliner21 on October 21, 2002, at 16:31:34
Borderliner -
Zyprexa - was that your first antipsychotic? Whatever was your first (Zyprexa is one of them) - caused your dystonia. Concurrent meds like Paxil can increase risk but only DA blocker will cause it virtually 100% of time.
Chad
> FOr those people taking zyprexa for depression and anxiety reasons, what dosage worked best for you along with your AD's. I find 3.75 mg works the best for me. 5 mg gives me akathesia.
Posted by chad_3 on October 21, 2002, at 23:00:50
In reply to zyprexa dose, posted by borderliner21 on October 21, 2002, at 16:31:34
So you're Dr. told you what about dystonia? Anything at all?
Jesus I can't believe some of these guys are such jerks. Seems like most patients don't blame the zyprexa or risperdal because it always seems to "help" dystonia (it MASKS it - it also CAUSES it).
I think I will need to do an info site on tardive movements sometime - kinda like my SP site.
Good luck guy.
Chad
http://www.socialfear.com/
> FOr those people taking zyprexa for depression and anxiety reasons, what dosage worked best for you along with your AD's. I find 3.75 mg works the best for me. 5 mg gives me akathesia.
Posted by McPac on October 21, 2002, at 23:31:12
In reply to Zyprexa - or earlier DA blocker caused dystonia, posted by chad_3 on October 21, 2002, at 22:57:01
"Whatever was your first (Zyprexa is one of them) - caused your dystonia."
>>>>>>>>>>Chad, is this some kind of 'rule' that someone's first anti-psychotic drug is the one that caused their movement disorder?
Also, what can somebody due to reverse these abnormal movements? anything?
Thanks!
Posted by Denise528 on October 22, 2002, at 7:53:23
In reply to Zyprexa - or earlier DA blocker caused dystonia, posted by chad_3 on October 21, 2002, at 22:57:01
Hi,
I have found that 10mg of Zyprexa taken every 5 days has helped me immensely. I didn't experence any EPS symptoms, maybe it's more common to men than women.
Denise
Posted by Kari on October 22, 2002, at 12:43:19
In reply to Re: Zyprexa - or earlier DA blocker caused dystonia, posted by Denise528 on October 22, 2002, at 7:53:23
Denise,
Is it safe to go on and off like that? I was once told that this can increase the risk for TD.
Posted by chad_3 on October 22, 2002, at 19:46:13
In reply to chad 3 Re: Zyprexa - or earlier DA blocker caused , posted by McPac on October 21, 2002, at 23:31:12
McPac-
I forgot about something. Stimulants - especially L-Dopa or illegal DA agonists like cocaine may induce dyskinesia (generally I think this is on "rebound" when DA goes very low). Normally this is L-DOPA in Parkinson's patients...
But other than that - DA blockers yes are the cause. I have seen a few case reports of cases possibly caused by other psychotopics but I would say probably 99%+ percent of this is DA blockers.
"Tardive" means "long term" (more than one month) - but "acute" dystonia (less than 3 days) - can occur with other drugs - such as a sensitive individual who takes meds like you mentioned Zoloft, or an anticonvulsant. If you get acute dystonia and never took DA blockers, you are probably very sensitive to DA blocker tardive movements...
Chad
http://www.socialfear.com/> "Whatever was your first (Zyprexa is one of them) - caused your dystonia."
>
> >>>>>>>>>>Chad, is this some kind of 'rule' that someone's first anti-psychotic drug is the one that caused their movement disorder?
> Also, what can somebody due to reverse these abnormal movements? anything?
> Thanks!
Posted by Denise528 on October 23, 2002, at 17:58:49
In reply to Re: Zyprexa - or earlier DA blocker caused dystonia, posted by Kari on October 22, 2002, at 12:43:19
Kari,
I hope that istn't the case 10mg of zyprexa is the only thing that seems to make me feel any good. My psychiatrist wanted me to take it every day but I thought by taking it every 5 days, I would have less chance of getting TD but perhaps I'm wrong. I haven't actually taken it for over two months now because I'm reluctant to take it at all. Sometimes though I'm really tempted to take one though just to have a few good days.
I know that one taken every 5 days would suit me as it takes about 5 days for the effects to wear off and then I start feeling down again.
Anyway I am going to pursue all other avenues before resorting to Zyprexa.
Denise
Posted by McPac on October 23, 2002, at 18:24:02
In reply to Re: Zyprexa - or earlier DA blocker caused dystonia, posted by Denise528 on October 23, 2002, at 17:58:49
Thanks for your replies.
Also, what can someone do about these abnormal movements other than taking these DA drugs to cover the movements up?
Posted by Mr Beev on October 23, 2002, at 20:38:31
In reply to chad 3 Re: Zyprexa - or earlier DA blocker , posted by McPac on October 23, 2002, at 18:24:02
> Also, what can someone do about these abnormal movements other than taking these DA drugs to cover the movements up?
My apologies for jumping in here, but from what I have read, if the meds are inducing abnormal movements one should never attempt to cover them up, but should discontinue the medication, if at all possible.
The reason is that continued use of the med may well make the movement disorders permanent! When ceasing the med, it can take months for the abnormal movements to cease in some people. With others, the condition is permanent. No one seems to know why some people are not affected, while others eventually return to normal after stopping the med, and yet others are permanently affected.
Newer, so-called atypical neurleptics, such as zyprexa, are supposed to have much lower incidences of TD. This is just what I've read.
I have been taking zyprexa infrequently for a half year or so with no troubles. There are occasions when it has quite saved the day.
Best regards,
Mr Beev
Posted by Kari on October 24, 2002, at 15:55:33
In reply to Re: Zyprexa - or earlier DA blocker caused dystonia, posted by Denise528 on October 23, 2002, at 17:58:49
Hi Denise,
Yes, it is very tempting to take something that has a good effect. It is too bad that taking dopamine blockers has to be so complicated :)
I hope you find an alternative that suits you.Kari.
This is the end of the thread.
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