Psycho-Babble Medication Thread 115979

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Mania Precipitator?

Posted by Bart1 on August 10, 2002, at 19:08:57

As a long term bipolar, my manic phase has been mild, about 3 days in length, and generally signaled by two or three sleepless nights. This past episode lasted more than 3 weeks. At the start, I was taking care of my neighbor's four small dogs and one bird. I believe I had an alergic reaction. Also, at about the same time, had bronchitis and took the antibiotics perscribed by my internist.

I know it sounds far out (no one else will listen or take me seriously) but, while I was taking care of the dogs, I was bitten many times by mesquitos. There was also mildew on the wall near my bed as a result of a leak in an external drain.

Thus, I see a pet alergy or bug bites (West Nile Virus?) or the mildew causing the bronchitis resulting in the antibiotics. Could any of these variable have precipitated my lenghthy manic episode?

 

Re: Mania Precipitator?

Posted by Jackd on August 10, 2002, at 23:51:54

In reply to Mania Precipitator?, posted by Bart1 on August 10, 2002, at 19:08:57

"Antimicrobial-induced mania (antibiomania): a review of spontaneous reports.

Abouesh A, Stone C, Hobbs WR.

Southern Virginia Mental Health Institute, Danville, VA 24541, USA.

The authors reviewed reported cases of antibiotic-induced manic episodes by means of a MEDLINE and PsychLit search for reports of antibiotic-induced mania. Unpublished reports were requested from the World Health Organization (WHO) and the Food and Drug Administration (FDA). Twenty-one reports of antimicrobial-induced mania were found in the literature. There were 6 cases implicating clarithromycin, 13 implicating isoniazid, and 1 case each implicating erythromycin and amoxicillin. The WHO reported 82 cases. Of these, clarithromycin was implicated in 23 (27.6%) cases, ciprofloxacin in 12 (14.4%) cases, and ofloxacin in 10 (12%) cases. Cotrimoxazole, metronidazole, and erythromycin were involved in 15 reported manic episodes. Cases reported by the FDA showed clarithromycin and ciprofloxacin to be the most frequently associated with the development of mania. Statistical analysis of the data would not have demonstrated a significant statistical correlative risk and was therefore not undertaken. Patients have an increased risk of developing mania while being treated with antimicrobials. Although this is not a statistically significant risk, physicians must be aware of the effect and reversibility. Further research clearly is required to determine the incidence of antimicrobial-induced mania, the relative risk factors of developing an antimicrobial-induced manic episode among various demographic populations, and the incidence of patients who continue to have persistent affective disorders once the initial episode, which occurs while the patient is taking antibiotics, subsides. The authors elected to name this syndrome "antibiomania."

Publication Types:
Review
Review, Tutorial

PMID: 11799346 [PubMed - indexed for MEDLINE] "

Best I could do bro.

 

Re: Mania Precipitator?

Posted by Jackd on August 10, 2002, at 23:55:47

In reply to Mania Precipitator?, posted by Bart1 on August 10, 2002, at 19:08:57

Oh also, bipolar stages can often be seasonal, as are many depressions. This can rationally be explained by work, social and climatic circumstances, but could it be possible that there sometimes exists a correlation between allergy seasons and these psychological phenomena? Who knows.

 

Re: Mania Precipitator?

Posted by littlebaldy29 on August 11, 2002, at 14:22:21

In reply to Re: Mania Precipitator?, posted by Jackd on August 10, 2002, at 23:55:47

My therapist strongly advocated for allergy testing for me, as I have manic depression. She has had manic depressive patients who have been triggered into episodes by allergens which may explain why we have such a seasonal component to our cycles... your assumptions are not as strange as you think!


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