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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by rjk on July 17, 2002, at 2:34:11
I combined Remeron with Effexor and it was the biggest mistake of my life. Since then I have had extreme reactions to any drugs that I have taken and my brain is now so sensitive to any form of drug that I literally cannot now even take an aspirin.
I would urge anyone who is thinking about combining meds only to do so as a last resort. They obviously work for some people, but for me it was a BIG mistake.
Personally I think that psychiatrists are too keen to start experimenting on people with combos that have no track record. Also, many psychiatrists do not consider that there are any benefits from doing so.
Posted by Shawn. T. on July 17, 2002, at 3:28:17
In reply to Combining meds can be a big mistake!, posted by rjk on July 17, 2002, at 2:34:11
I apologize if anyone read comments from me about mixing Remeron with Effexor. I think that Effexor can pose some serious problems when mixed with Remeron. Combining meds is a big mistake if you don't do your own detective work on how the two interact. I made the mistake of taking the advice of others on that issue. I'd like to show you this; I was digging through Organon's list of ligands. I found that a drug called Sertindole seemed to have remarkable efficacy for schizophrenia. See
http://www.gpcr.org/7tm/ligand/Organon/Tablig/LIG_C106516249.htmland
http://www.schizophrenia.com/news/sertindole.html
So I believe that this is the most effective drug for schizophrenia currently approved in the US. It is amazing. Ditch that Zyprexa or Risperdal and get this drug. How does very little chance of weight gain sound? How about no effects on prolactin? Just do it.
Shawn
Posted by oracle on July 17, 2002, at 14:14:06
In reply to Combining meds can be a big mistake!, posted by rjk on July 17, 2002, at 2:34:11
With few problems. And done poly-drug treatment
since 1995; single drug treatment failed for me.
One does have to take care when you mix meds.
Posted by SLS on July 17, 2002, at 21:39:40
In reply to Combining meds can be a big mistake!, posted by rjk on July 17, 2002, at 2:34:11
> Combining meds can be a big mistake!
Of course - as in all medicinally-treated illnesses.
However, for many, it is a life-saver and no less than a genuine miracle.
- Scott
Posted by Shawn. T. on July 17, 2002, at 22:55:17
In reply to Re: Combining meds can be a big mistake! » rjk, posted by Shawn. T. on July 17, 2002, at 3:28:17
Note that anyone taking sertindole should consult with their doctor about getting on a beta blocker that doesn't interact with sertindole.
Shawn
Posted by rjk on July 18, 2002, at 3:27:50
In reply to Re: Combining meds can be a big mistake! » Shawn. T., posted by Shawn. T. on July 17, 2002, at 22:55:17
Because mine wrote to me to tell me to combine meds and then when I experienced problems wrote to me to tell me to increase the dose. I am now trying to sue him for negligence.
Posted by Sleepy Lizard on July 18, 2002, at 9:22:30
In reply to I have taken Remeron + Effexor since 1997, posted by oracle on July 17, 2002, at 14:14:06
Did you have the sexual side effects with the combination of Remeron and Effexor? I take Effexor XR and the delayed ejaculation and anorgaxsmia is worse that it was with Paxil or Celexa.
Posted by oracle on July 18, 2002, at 11:07:25
In reply to Re: I have taken Remeron + Effexor since 1997 » oracle, posted by Sleepy Lizard on July 18, 2002, at 9:22:30
For me, all AD's decrease intrest. But none have
ever effected functioning.
Posted by cybercafe on July 18, 2002, at 12:50:34
In reply to So why aren't psychiatrists more cautious?, posted by rjk on July 18, 2002, at 3:27:50
> Because mine wrote to me to tell me to combine meds and then when I experienced problems wrote to me to tell me to increase the dose. I am now trying to sue him for negligence.
i have never taken it myself, but some people say the side effects on remeron get more manageable at higher dosages....
... i also hear that it is remeron alone which has an incidence of autistic spacing....
... so it's weird because it was suggested to me by a professional that remeron would be taken off the market... BUT it was also suggested by a few
http://www.google.ca/search?q=david+healy+ssri&ie=ISO-8859-1&hl=en&meta=that SSRIs cause agitation and suicide in many... including healthy volunteers with no history of depression.... but we still perscribe SSRIs ...
but i am totally in no position to comment on your case as i have no clue how bad your side effects were etc etc
good luck
cybercafe :)
Posted by dave40252 on July 18, 2002, at 13:26:22
In reply to Combining meds can be a big mistake!, posted by rjk on July 17, 2002, at 2:34:11
It is impossible to make blanket statements like that. Combining meds CAN and DOES work for many. I have been on many different combinations of AD's. You need to have a doc who knows what they are doing, you have to educate yourself as to the profiles, etc of the drugs, and you need to be methodical when adding a new one or discontinuing an old one.
And this really isnt specific to AD's - you have to be careful when combing meds of all types.
Posted by Shawn. T. on July 18, 2002, at 20:36:17
In reply to Re: So why aren't psychiatrists more cautious?, posted by cybercafe on July 18, 2002, at 12:50:34
I believe that higher doses of Remeron result in more side effects. I'm a huge fan of mixing 7.5mg/day of Remeron with dietary supplements.
A dose of 7.5mg - 15mg/day is reasonable in my opinion. All of this business about increasing the dosage of drugs if they don't work is nonsense when it leads to more side effects. I'm not a big fan of giving people alpha-2-antagonists just to help them lose weight. There are much more intelligent ways to go about it.
There are plenty of dietary supplements to counteract the weight gain caused by Remeron's indirect effects on cholesterol levels.
http://www.gnc.com/health_notes/Concern/High_Cholesterol.htmYou guys have got to stop consuming lots of caffeine and sugar. Cut caffeine entirely out of your diet if you really want to feel better. Use that GNC site; it provides references. I know it's commercial, but who else could afford to put all of that information together in one place. Be sure that you talk to your doctor about what dietary supplements you choose to take. Don't take 5-HTP unless you are on a drug that blocks
5-HT2 receptors. The GI side effects can be prevented by a 5-HT3 antagonist (this may or may not be a good idea). I'm not really crazy about 5-HTP at all, but it's your decision to make.
Side effects should be entirely avoidable no matter what drug you take. Either decrease the dosage or try something else (but non an SSRI if you really want to help yourself). Sometimes mixing drugs works, but don't forget to talk to your doctor. You need to know exactly what is going wrong in your body to treat any mental disorder you may have. Work with your doctor to figure out what the problems are. Don't take anything that you feel uncomfortable taking (with regards to drugs for depression and anxiety). That just leads to stress and reduced efficacy.On dietary supplements for depression:
http://www.gnc.com/health_notes/Concern/Depression.htmOn dietary supplements for anxiety:
http://www.gnc.com/health_notes/Concern/Anxiety.htmOn dietary supplements for ADHD:
http://www.gnc.com/health_notes/Concern/ADD.htm
Shawn
Posted by rjk on July 19, 2002, at 7:09:30
In reply to Your serotonin transporter is probably just fine!, posted by Shawn. T. on July 18, 2002, at 20:36:17
Posted by Shawn. T. on July 20, 2002, at 23:53:26
In reply to Shawn, you should be a psychiatrist! (nm), posted by rjk on July 19, 2002, at 7:09:30
This is the end of the thread.
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