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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Bissie66 on February 18, 2002, at 12:12:26
I don't remember the name of it, but I signed up for a study and will be taking it for 8 months (1st 2 months 50/50 chance of placebo). The dr. told me it is the same molecule as Celexa, but they split it, and found that they got rid of most of the adverse side effects by doing that, including sexual dysfunction. He also told me it would be released by FDA in June. Does anyone know anything about this? I'm wondering if it's as good as they claim. I hope so!
Posted by ross on February 18, 2002, at 14:34:36
In reply to Has anyone heard of new A.D. due out in June? (m), posted by Bissie66 on February 18, 2002, at 12:12:26
the new medication is from forest labs and it is called Lexapro. it is almost identicle to Celexa. it will have less side effects but unfornatly it still will have the same rate of sexual side effects as celexa and other ssri's.
also in late 2002 Lilly will come out with Duloxetine very similar to Effexor. Lilly claims it is more potent then Paxil. you can read about all these on their websites or on medscape
ross
Posted by Anyuser on February 18, 2002, at 18:15:50
In reply to Re: Has anyone heard of new A.D. due out in June? (m), posted by ross on February 18, 2002, at 14:34:36
What is your source of info re sexual side effects of Lexapro?
Posted by christophrejmc on February 18, 2002, at 22:39:32
In reply to Has anyone heard of new A.D. due out in June? (m), posted by Bissie66 on February 18, 2002, at 12:12:26
A lot of people think this is just a gimmick to extend the patent of Celexa.
Celexa (citalopram) contains the R- and S- enantiomers (just means it contains equal amounts of molecules that have different atomic ordering -- called a racemic mixture). Lexapro (escitalopram) only contains the S- enantiomer (the R- (right) enantiomer is thought to have no anti-depressant effect and may be responsible for some of the side-effects). They probably knew about this all along, but decided to release Celexa just so they could later introduce a new-and-improved version to capture market share they would've lost from Celexa going generic. (Incidentally, S-, as in S-citalopram, stands for sinister (meaning left) -- irony?)
-Christophre
Hmm.. my knowledge of chemistry (especially stereochemistry) is pitiful, someone correct me if I've made a mistake.
Posted by Bill L on February 19, 2002, at 7:58:07
In reply to Has anyone heard of new A.D. due out in June? (m), posted by Bissie66 on February 18, 2002, at 12:12:26
Lexapro is the name of the medication. It is an enantiomer of Celexa. In clinical studies it produced less side effects than Celexa in 2 areas:
1) day time tiredness, and
2) sexual dysfunctionI think that it will be an excellent drug.
Posted by Patson on August 19, 2002, at 23:04:43
In reply to Re: Lexapro, posted by christophrejmc on February 18, 2002, at 22:39:32
> A lot of people think this is just a gimmick to extend the patent of Celexa.
>I don't think Celexa's patent runs out for at least another year due to an extension for pediatric studies. Further, it takes up to 18 months for a generic to be approved as "equal" by the FDA. That means generic citalopram won't be available until... 2005?
> Celexa (citalopram) contains the R- and S- enantiomers (just means it contains equal amounts of molecules that have different atomic ordering -- called a racemic mixture). Lexapro (escitalopram) only contains the S- enantiomer (the R- (right) enantiomer is thought to have no anti-depressant effect and may be responsible for some of the side-effects). They probably knew about this all along, but decided to release Celexa just so they could later introduce a new-and-improved version to capture market share they would've lost from Celexa going generic. (Incidentally, S-, as in S-citalopram, stands for sinister (meaning left) -- irony?)
>
> -Christophre
>
> Hmm.. my knowledge of chemistry (especially stereochemistry) is pitiful, someone correct me if I've made a mistake.
>
>
Posted by jay60 on August 20, 2002, at 6:50:06
In reply to Re: Lexapro, posted by Patson on August 19, 2002, at 23:04:43
Have you considered that they may have just recently developed the ability to separate the R- (right) enantiomer from the S- enantiomer, are have just advanced the technology to a point were it is cost effective to separate then. Some of you people are just so cynical. about thinks you know nothing about (ex. chemistry).
Posted by Dr. Bob on August 20, 2002, at 8:01:59
In reply to Re: Lexapro, posted by jay60 on August 20, 2002, at 6:50:06
> Some of you people are just so cynical. about thinks you know nothing about (ex. chemistry).
It's great to add a different perspective, but please don't post anything that could lead others to feel accused or put down:
http://www.dr-bob.org/babble/faq.html#civil
Bob
PS: Follow-ups regarding posting policies, and complaints about posts, should be redirected to Psycho-Babble Administration; otherwise, they may be deleted.
This is the end of the thread.
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