Psycho-Babble Medication Thread 66230

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desipramine/nadolol/clonidine w/stims for ADHD??

Posted by MissyMissy on June 12, 2001, at 14:36:38

Still trying to find the right combo for ADHD... I've read a lot about the above being combined with Adderall or other stims to help control aggressiveness, tantrums, frustration tolerance, etc. Any experiences with these drugs or other combinations with stims??


Re: desipramine/nadolol/clonidine w/stims for ADHD?? MissyMissy

Posted by SalArmy4me on June 12, 2001, at 15:50:15

In reply to desipramine/nadolol/clonidine w/stims for ADHD??, posted by MissyMissy on June 12, 2001, at 14:36:38

Out of all those, you might benefit from desipramine alone:
Wilens, Timothy E. MD et al. Six-Week, Double-Blind, Placebo-Controlled Study of Desipramine for Adult Attention Deficit Hyperactivity Disorder. American Journal of Psychiatry. 153(9):1147-1153, September 1996:

"...The magnitude of the reduction in ADHD symptoms with desipramine is similar to that reported in adults with ADHD who received robust doses of methylphenidate. Like methylphenidate, desipramine treatment resulted in significant reductions in the broad categories of inattention, impulsivity, and hyperactivity. The current findings with desipramine, together with previously reported findings with psychostimulants, support the notion that pharmacological agents effective in reducing ADHD symptoms appear to operate through their catecholaminergic properties..."

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