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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Tori on October 26, 2000, at 9:26:40
Hi,
I am on 40 mg parnate a day for about six weeks now. MY BP used to be perfect, 120/80 range, now it is normally 80/60 or lower than that. What are the main physical implications of having hypotension over the long term?
Also, when you go into a hypertensive crisis, same thing, what are the long-term physical risks? Highest I've gone is 170/110. I know what *physically* happens when you go hyper- but searching the net has been fruitless in terms of finding out what these meds will do to a 26-year old in the long term with being a mixed state of hypo- or hyper-tensive.
I don't feel *that* great on these meds, just don't feel suicidal. I am physically exhausted, falling asleep all the time, insomnia.... my hair is falling out, too...which makes me think I should get more of a better thyroid test done...... sorry to get offf track there ........
I think I'll give up on it if after the dosage is increased (heard it can be up to 90 mg) and still nothing; I don't want to give it up now like any normal AD because of the sheer hell I went through going off AD's for two weeks in order to start this med.
BTW it is augmented with 300 mg lamotrigine a day, plus 2-6 mg clonazepam as needed.
Thanks for any advice!!!Tori :-)
Posted by danf on October 26, 2000, at 16:32:58
In reply to PARNATE-Side Effects of hyper/hypotension, posted by Tori on October 26, 2000, at 9:26:40
'Low BP' in the 80/60 range
This a normal range for many women & there is no associated problem UNLESS you have some type of symptom, such as fainting, which would be unusual. There are no long term health issues.
another part of this 'problem' would be if you HR & BP failed to increase in response to exercise & other normal stimuli.
elevated BP is different.. a BP of 150/100 is associated with an increased risk of about 5% per yr for stroke or heart attack.
Higher BPs increase the risk.
short term acute increases in BP have no known health risk, if they are physiologic. Bp increases with exercise normally to the 170 to 200 over 100 to 110 range. Also to the same range with coughing & straining with a BM.
Very high SUSTAINED BP for no 'normal' reason, leads to kidney damage & failure. There are usually hormonal changes associated with the sustained elevation of BP ( like renin & angiotensin ). The elevated hormone levels are implicated in kidney, brain & heart damage.
This is why BP is checked in the resting state
Posted by JahL on October 26, 2000, at 17:20:16
In reply to PARNATE-Side Effects of hyper/hypotension, posted by Tori on October 26, 2000, at 9:26:40
Tori,
can't help you with the hypertention bit but having trialled Parnate, phenelzine & moclobemide at high doses I can tell you that in my experience, with the irreversible MAOIs increases in dosage bring about an exponential increase in sinister side effects (far unlike those of other ADs) I normally take side-effects in my stride but above a v specific dose Parnate knocked me cold and phenelzine would give me blackouts and intense derealisation.Potentially dangerous meds like these should make you feel better than 'OK'. Hope yr lucks better than mine,
Jah.
Posted by JahL on October 26, 2000, at 17:31:22
In reply to PARNATE-Side Effects of hyper/hypotension, posted by Tori on October 26, 2000, at 9:26:40
P.S. The insomnia, especially on phenelzine, is unrelenting. Far worse than on ANY chemical I've ever tried, and I've tried a few.;)
Posted by Tori on October 26, 2000, at 23:30:25
In reply to Re: PARNATE-Side Effects of hyper/hypotension, posted by JahL on October 26, 2000, at 17:31:22
Thanks all for your helpful answers. :-) Now I'm going to try to get some sleep.
This is the end of the thread.
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