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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by phillybob on February 28, 2000, at 17:51:01
Okay, I've narrowed my general question to two and started this new thread so that you don't have to climb through my prior thread and its accompanying erronous additional ones.
(1) Do those who've been on an MAOI but stopped due to it "pooping out" (or for whatever other reason) actually experience their illness worse after being off than prior to ever haven taken the MAOI? Is the help of other meds after never as effective as those meds had been prior to taking an MAOI?
(2) Are there lifetime MAOI success stories? I hear a bit about the "pooping out" but not any "I've been on it for my entire life with success and now I am a ripe old age of ... how old are you Noa? :)"
Again, thanks for your help (and thanks for to the one person who has emailed me dirctly for helping me clarify my concerns).
Posted by Noa on February 28, 2000, at 18:39:11
In reply to 2 MAOI Questions, posted by phillybob on February 28, 2000, at 17:51:01
Grrr, ok phillybob, I'll take that as a sign of affection.
I have not been on any MAOs, BTW, and most of the drugs I am on are younger than me by far, so you'd have to stick around a while to see what happens. Actually even the older drugs (Lithium, ritalin) I have only been on a short time.
How old are the MAOIs, btw? My impression is they have been around a while, so it could be there is someone here who has been on one for a long time, but it is also my impression that there were decades when these drugs were out of style.
Anyway, you ask excellent question, and I hope you get answers.
BTW, are you sure you're not newyork bob in disguise? Funny how he hasn't been here a few days and you have......hmmmmmm.....
Posted by phillybob on February 28, 2000, at 19:13:42
In reply to Re: 2 MAOI Questions, posted by Noa on February 28, 2000, at 18:39:11
Noa, it was affection. I as well as many others probably have some good answers to your MAOI queries. Just email me and I can share the knowledge I have as I don't want to clutter up this post too much with the info that I've already obtained (by the way, I am not nybob; I really am a new visitor)
> Grrr, ok phillybob, I'll take that as a sign of affection.
>
> I have not been on any MAOs, BTW, and most of the drugs I am on are younger than me by far, so you'd have to stick around a while to see what happens. Actually even the older drugs (Lithium, ritalin) I have only been on a short time.
>
> How old are the MAOIs, btw? My impression is they have been around a while, so it could be there is someone here who has been on one for a long time, but it is also my impression that there were decades when these drugs were out of style.
>
> Anyway, you ask excellent question, and I hope you get answers.
>
> BTW, are you sure you're not newyork bob in disguise? Funny how he hasn't been here a few days and you have......hmmmmmm.....
Posted by Adam on February 28, 2000, at 22:11:08
In reply to Re: 2 MAOI Questions, posted by Noa on February 28, 2000, at 18:39:11
MAOIs have "been around" since the 1950s. The first MAOI, iproniazid, I think, was used originally as a treatment for tuberculosis. In a clinical trial on elderly patients in a VA hospital, it was found quite by accident to be a mood-elevator as well, and became the firt viable antidepressant. It has since been retired and replaced by less hepatotoxic drugs of the same class.
I've only been on one for about six months. I fear the dreaded poop-out as well, but at this point things are going pretty well. No return to anything near as severe as what I once experienced, and, for the record, an MAOI has been the only kind of drug (and I took a bunch) that has really worked for me.
> Grrr, ok phillybob, I'll take that as a sign of affection.
>
> I have not been on any MAOs, BTW, and most of the drugs I am on are younger than me by far, so you'd have to stick around a while to see what happens. Actually even the older drugs (Lithium, ritalin) I have only been on a short time.
>
> How old are the MAOIs, btw? My impression is they have been around a while, so it could be there is someone here who has been on one for a long time, but it is also my impression that there were decades when these drugs were out of style.
>
> Anyway, you ask excellent question, and I hope you get answers.
>
> BTW, are you sure you're not newyork bob in disguise? Funny how he hasn't been here a few days and you have......hmmmmmm.....
Posted by S. Suggs on February 29, 2000, at 5:39:39
In reply to 2 MAOI Questions, posted by phillybob on February 28, 2000, at 17:51:01
Hello: I currently take parnate vs. nardil. It typically has more of a stimulant effect on some people. I had to up my dose to 80 mg/day. I has worked well after trying drug after drug for 5 years. I am dysthymic and add-h. I also take lithium plus t3.
The maoi's are the only class that have worked for this extended period time, not long for some (4 mo.) I'd suggest you search the archives on this post, since there is a lot of info to be found. Blessings,
S. Suggs
Posted by Seamus on March 1, 2000, at 12:11:05
In reply to 2 MAOI Questions, posted by phillybob on February 28, 2000, at 17:51:01
I ran the gamut of TCI's before settling on Nardil.
Was happy as a clam (well, just normal) for years, then switched to Parnate five or six years ago due to anorgasmia.
I've only had one Tyramine reaction, and that was after eating half a pound of salami. I do watch my diet, for the most part.
I added a grain of Armour Thyroid about a year ago, primarily to treat "sub-clinical hypo-throidism" and found I could reduce my dose to 10 mg BID.
The biggest problem is remembering to take the stuff! You also need to remember the hell which will ensue if you don't.
Long time user.
Regards,
Seamus
Posted by Sigolene on March 1, 2000, at 14:53:30
In reply to 2 MAOI Questions, posted by phillybob on February 28, 2000, at 17:51:01
> Okay, I've narrowed my general question to two and started this new thread so that you don't have to climb through my prior thread and its accompanying erronous additional ones.
>
> (1) Do those who've been on an MAOI but stopped due to it "pooping out" (or for whatever other reason) actually experience their illness worse after being off than prior to ever haven taken the MAOI?No, I stopped these meds but I didn't feel worse after. Only the same as before.
Sigolene
Posted by Elizabeth on March 1, 2000, at 23:39:08
In reply to 2 MAOI Questions, posted by phillybob on February 28, 2000, at 17:51:01
> (1) Do those who've been on an MAOI but stopped due to it "pooping out" (or for whatever other reason) actually experience their illness worse after being off than prior to ever haven taken the MAOI?
There's a withdrawal syndrome that is definitely horrible (qualitatively different from depression, for me anyway), but not permanent.
> Is the help of other meds after never as effective as those meds had been prior to taking an MAOI?
Antidepressants didn't seem to help with the withdrawal syndrome after Nardil pooped out. Xanax and Klonopin did help some.
MAOIs, including Nardil, worked again after I went for a couple months without taking them.
> (2) Are there lifetime MAOI success stories? I hear a bit about the "pooping out" but not any "I've been on it for my entire life with success and now I am a ripe old age of ... how old are you Noa? :)"
Hmm. Well, my pdoc once mentioned that except for me, all his patients who are on Parnate have been on it for many years. I take this as a good sign.
BTW, nice to meet you. :-)
This is the end of the thread.
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