Psycho-Babble Psychology Thread 1078649

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Anyone tried Riluzole or other NMDA anatgonists?

Posted by kilo8 on May 3, 2015, at 23:03:23

I'd really like to try this but I fear it will be hard to get a prescription for it.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754299/

 

Re: Anyone tried Riluzole or other NMDA anatgonists? » kilo8

Posted by SLS on May 6, 2015, at 16:55:32

In reply to Anyone tried Riluzole or other NMDA anatgonists?, posted by kilo8 on May 3, 2015, at 23:03:23

> I'd really like to try this but I fear it will be hard to get a prescription for it.
>
> http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754299/

For me, riluzole was an unconscionably expensive sugar pill. I felt neither better nor worse with respect to bipolar depression. I tried memantine 20 mg/day for a few weeks. I didn't take it long enough, nor did I take a high enough dosage. Lamictal might be helpful in that it inhibits glutamate release, thus reducing the stimulation of NMDA receptors.


- Scott

 

Re: Anyone tried Riluzole or other NMDA anatgonists?

Posted by kilo8 on May 7, 2015, at 0:25:35

In reply to Re: Anyone tried Riluzole or other NMDA anatgonists? » kilo8, posted by SLS on May 6, 2015, at 16:55:32

Hello,
but isnt 20mg memantine the standard dose for alzheimers? How much would you need for depression/ocd?

What worries me about lamictal is side effects. I read lamictal builds up in the retina of the eye and that they dont know if this is safe on the long run. :/

 

Re: Anyone tried Riluzole or other NMDA anatgonists? » kilo8

Posted by phidippus on July 28, 2015, at 15:35:53

In reply to Anyone tried Riluzole or other NMDA anatgonists?, posted by kilo8 on May 3, 2015, at 23:03:23

Riluzole is a glutamate inhibitor, not an NMDA antagonist. Namenda is a NMDA antagonist. Other drugs that are glutamate inhibitors are Keppra, Lyrica, Zonegran, Lamictal and Topemax.

Eric

ps. they are taken in conjunction with an SSRI

 

Re: Anyone tried Riluzole or other NMDA anatgonists?

Posted by kilo8 on September 9, 2015, at 12:44:01

In reply to Re: Anyone tried Riluzole or other NMDA anatgonists? » kilo8, posted by phidippus on July 28, 2015, at 15:35:53

I dont think I could get riluzole. I think it's also expensive.

I just started with Lamotrigine but I don't think that Lamotrigine is as strong as riluzole. I read about someone who had depression his whole life and nothing worked and when he started riluzole he felt a difference within a week or so. This drug must be very potent.

 

Re: Anyone tried Riluzole or other NMDA anatgonists? » kilo8

Posted by phidippus on September 15, 2015, at 20:52:36

In reply to Re: Anyone tried Riluzole or other NMDA anatgonists?, posted by kilo8 on September 9, 2015, at 12:44:01

Riluzole shouldn't be prohibitively expensive.

Eric


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