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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by john1022 on October 29, 2003, at 10:02:58
I have read that there are different types of inositol. I am looking for the inositol which is MYO-insitol to treat depression.
I bought some Inositol from Vitamin World in powder form (1000mg). The lady working there had not heard of the different types of inositol and was not sure if the inositol I bought was the correct type (myo).
I just want to be sure I am taking the right type that has been proven effective for treating depression. Does anyone know if this is the right type? If not, where would I find myo-inositol? Thanks for the help
Posted by JLx on October 30, 2003, at 8:54:51
In reply to The right type of Inositol...MYO?, posted by john1022 on October 29, 2003, at 10:02:58
> I have read that there are different types of inositol. I am looking for the inositol which is MYO-insitol to treat depression.
>
> I bought some Inositol from Vitamin World in powder form (1000mg). The lady working there had not heard of the different types of inositol and was not sure if the inositol I bought was the correct type (myo).
>
> I just want to be sure I am taking the right type that has been proven effective for treating depression. Does anyone know if this is the right type? If not, where would I find myo-inositol? Thanks for the helpFWIW, on the iherb site, under the Jarrow Formula description of inositol, it says simply that inositol is the common term for myo-inositol. (I looked up Jarrow because it was recommended by Barbara Cat on this site.)
Perhaps when the physicians and scientists are referring to it they are just being more precise and it really is all the same thing?
Posted by john1022 on October 30, 2003, at 15:26:27
In reply to Re: The right type of Inositol...MYO? » john1022, posted by JLx on October 30, 2003, at 8:54:51
Thanks. I am pretty sure you are right on that. I think the normal "inositol" they sell as a powder in stores is actually "myo-inositol" like you said. Thanks for responding
Posted by JLx on November 2, 2003, at 9:47:23
In reply to Re: The right type of Inositol...MYO?, posted by john1022 on October 30, 2003, at 15:26:27
How much are you taking? I think the studies I've read of were as much as 12-18 grams/day. I haven't tried it because of that expense.
But recently on the Alernative Mental Health site, I was reading this, written by Dr. Walsh from the Pfeiffer Clinic. http://www.alternativementalhealth.com/articles/walshMP.htm#Ob
"Generally OCD patients respond nicely to methionine, SAMe, calcium, magnesium, B-6, inositol, TMG, and zinc. Most OCD patients get worse if given supplements of DMAE, choline, copper, or folic acid. 500 to 1000 mg/day of inositol will probably be needed to provide good response. (9 Jan, 2003)
A) Inositol is usually very helpful for UNDERMETHYLATED, HIGH HISTAMINE patients. This includes nearly every OCD patient we have seen. Inositol usually provides calming throughout the day and ability to settle down to sleep at night, for these patients.
B) On the other hand, OVERMETHYLATED patients usually derive little or no benefit from Inositol, and may experience very nasty side effects from it.
C) Although a couple thousand milligrams may be needed to do the job & the tablets are often quite large, Inositol has the great advantage of being palatable..... Many of our patients chew it before swallowing, and report it "doesn't taste bad at all".
I'm quite surprised that Inositol isn't more popular due to its effectiveness and its role as a major "second messinger" in neurotransmission."
I don't have a diagnosis of OCD but since there is so much overlap to these things, I found that interesting, especially that apparently even as little as 500 mg or 1 gm might be helpful.
He says under the SAMe article that a trial of SAMe where the patient responds positively is a good indication of undermethylation, which is me. I have been taking an inositol/choline combo with 250 of each, which I think now was probably not a good idea, if choline is contraindicated for undermethylated people, especially as I've also been taking lecithin.
Be sure to let us know how the inositol works out for you.
> Thanks. I am pretty sure you are right on that. I think the normal "inositol" they sell as a powder in stores is actually "myo-inositol" like you said. Thanks for responding
Posted by john1022 on November 2, 2003, at 14:56:14
In reply to Re: The right type of Inositol...MYO? » john1022, posted by JLx on November 2, 2003, at 9:47:23
Thanks JLx for the info on the studies. I seem to experience more anxiety/depression than ocd. But I am pretty sure it is all serotonin related in my case and inositol has been shown to help resenitize serontin receptors.
I have been taking inositol at about 10 grams a day so far. The first few days I felt very much how I felt like when I was first on effexor (my jams would get tight and tense), so it almost seems like it might be having some action on serotonin like effexor. no luck on reduced anxiety or feeling "normal" yet. It has only been a week, so I will report back later.
I would try just around a gram a day, as that study and that doctor said it can be effective...but I also read somewhere that we get around a gram of inositol daily in our diet anyway, so I don't know how much more effective only a gram would be. But I have also read another study saying that 6 grams a day is effective as well, so I might cut back a little. Who knows though...thanks again for the input, hope you are feeling alright.
Posted by john1022 on November 2, 2003, at 17:53:07
In reply to Re: The right type of Inositol...MYO?, posted by john1022 on November 2, 2003, at 14:56:14
meant "jaws" are getting tense like when I was on effexor. The inositol does make me feel a little more relaxed at night time though, which is the time when my anxiety is the worst along with in the morning. I guess it might take another week or so for the inositol to kick in, apparently in has a delayed affect like ssri's. in the studies I guess the patients felt no positive effects after two weeks, but started to feel them after 4 weeks. I guess inositol has shown to slightly increase the density of 5ht2 receptors. I am hoping this works for me.
This is the end of the thread.
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