![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by PeterMartin on September 19, 2016, at 17:27:06
New study/article. Excerpt:Several years ago, a drug being tested in humans for treatment of Alzheimer's disease was shown to have "robust" effects in reducing psychotic symptoms in both Alzheimer's and schizophrenia patients. The drug activated "muscarinic" receptors in the brain that bind the neurotransmitter acetylcholine.
While the drug didn't make it to market, Conn and his colleagues seized on the possibility that activating muscarinic receptors could be a new way to treat schizophrenia.http://medicalxpress.com/news/2016-09-eye-potential-schizophrenia.html
Posted by Lamdage22 on September 20, 2016, at 7:43:15
In reply to Researchers eye potential schizophrenia 'switch', posted by PeterMartin on September 19, 2016, at 17:27:06
Thanks for sharing
Posted by Jonhed on October 17, 2016, at 16:35:37
In reply to Researchers eye potential schizophrenia 'switch', posted by PeterMartin on September 19, 2016, at 17:27:06
They have to go another way than with trihexylphenidyl then, cause the anticholinergic medications that was used to treat Alzheimer's before levodopa and dopamine agonists in general, causes psychotic symtoms.
Orphenadrine is one that they mainly used before, so I can very much believe that if the mechanism are reversed, it will be effective against positive symptoms of schizophrenia.
The problem I see in using muscarinic agents are the possible increase of negative symptoms.
I do look forward following the progress though.
Thanks for the link.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.