Psycho-Babble Medication Thread 1014646

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Is Seroquel a sigma agonist or angatonist?

Posted by Tomatheus on March 31, 2012, at 11:15:55

Hi,

I was reading on one of Dr. Bob's "psychopharmacology tips" pages (http://www.dr-bob.org/tips/split/Quetiapine.html) that Seroquel (quetiapine) has "potent effects" on sigma receptors. What I can't seem to find anywhere is whether Seroquel acts as an agonist or as an antagonist at sigma receptors. Do any of you know the answer to this question, and if you do, could you point me to a source that documents whether Seroquel is a sigma agonist or sigma antatonist?

Thanks,
Tomatheus

 

Re: Is Seroquel a sigma agonist or angatonist?

Posted by linkadge on April 1, 2012, at 17:50:28

In reply to Is Seroquel a sigma agonist or angatonist?, posted by Tomatheus on March 31, 2012, at 11:15:55

I thought I read somewhere that it was an antagonist.

Linkadge

 

Re: Is Seroquel a sigma agonist or angatonist? » linkadge

Posted by Tomatheus on April 1, 2012, at 18:28:35

In reply to Re: Is Seroquel a sigma agonist or angatonist?, posted by linkadge on April 1, 2012, at 17:50:28

Linkadge,

Thanks for your response.

Tomatheus


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