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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 13 of 13. This is the beginning of the thread.
Posted by DavidLa on August 17, 2008, at 22:27:34
I take Nardil for Social Phobia/Depression and am looking for something I can add that will address my OCD.
What OCD meds are safe to take with Nardil?
Which of these are generally considered most effective (ie, first-line treatments)?
Thanks,
DLA
Posted by Phillipa on August 17, 2008, at 23:56:42
In reply to What OCD meds are safe to take with Nardil?, posted by DavidLa on August 17, 2008, at 22:27:34
I'm not aware of any you can take with nardil. At first just anafranil and luvox were for OCD now I think all the SSRI's are approved. Phillipa
Posted by desolationrower on August 18, 2008, at 0:14:34
In reply to Re: What OCD meds are safe to take with Nardil? » DavidLa, posted by Phillipa on August 17, 2008, at 23:56:42
There are some things to try. Antipsychotic might be the easiest to get. Other options are inositol, memantine, or benzos.
Posted by desolationrower on August 18, 2008, at 0:31:32
In reply to Re: What OCD meds are safe to take with Nardil?, posted by desolationrower on August 18, 2008, at 0:14:34
Oh and opioids too. I'm not sure what ones you could get prescribed though; the only one i can think of offhand that is centrally acting and unscheduled is tramadol and thats a no-no with moais.
Posted by UGottaHaveHOPE on August 18, 2008, at 2:39:29
In reply to Re: What OCD meds are safe to take with Nardil?, posted by desolationrower on August 18, 2008, at 0:31:32
I could be mistaken, but I believe Nardil treats OCD.
Posted by dcruik518 on August 18, 2008, at 12:47:14
In reply to Re: What OCD meds are safe to take with Nardil?, posted by UGottaHaveHOPE on August 18, 2008, at 2:39:29
The problem with combining MAOIs with re-uptake inhibitors (i.e. either SSRIs or TCAs) is that of serotonin toxicity (serotonin syndrome). This reaction can only occur with antidepressants that posses potency as SRIs. Of the TCAs, this only includes imipramine and clomipramine. The other TCAs are safe to combine with the MAOIs because they do not posses significant SRI potency.
Posted by desolationrower on August 18, 2008, at 21:23:15
In reply to Re: What OCD meds are safe to take with Nardil?, posted by dcruik518 on August 18, 2008, at 12:47:14
Have any of the non-serotonergic trycyclics been shown to be helpful in OCD though?
Posted by DavidLA on August 18, 2008, at 23:17:44
In reply to What OCD meds are safe to take with Nardil?, posted by DavidLa on August 17, 2008, at 22:27:34
My pdoc prescribed Abilify. Any experiences?
Posted by dcruik518 on August 19, 2008, at 9:33:54
In reply to Re: What OCD meds are safe to take with Nardil?, posted by DavidLA on August 18, 2008, at 23:17:44
DavidLa,
I take abilify for what some p-docs have considered a kind of OCD but others consider more like a nervous tic. I have trichotillimania, or compulsive hair pulling. The abilify totally wipes out the hair pulling compulsion. Which makes me suspect it would work well for other OCD compulsions.
Posted by desolationrower on August 19, 2008, at 19:09:49
In reply to Re: What OCD meds are safe.. Abilify?, posted by dcruik518 on August 19, 2008, at 9:33:54
How long have you been on phenelzine? OCD sometimes requires longer to be helped by a drug trial. You might not need something else.
Posted by dcruik518 on August 20, 2008, at 17:25:22
In reply to Re: What OCD meds are safe to take with Nardil?, posted by desolationrower on August 18, 2008, at 21:23:15
> Have any of the non-serotonergic trycyclics been shown to be helpful in OCD though?
That's a good question, Desolation. I don't think they have been actually--just anafranil, which supposedly the best balanced serotenergic/norepinephrine AD. However, I think the NE and other effects of certain tricylcics could boost the effectivness of an MAOI. This may have something to do with down regulation of certain 5ht receptor, which is characteristic of nortriptyline when combined with SSRIs.
Posted by aussie_jon on August 23, 2008, at 3:11:39
In reply to Re: desolationthrower, posted by dcruik518 on August 20, 2008, at 17:25:22
"Have any of the non-serotonergic trycyclics been shown to be helpful in OCD though?"
No, only Clomipramine
If Phenelzine isnt working, maybe the dose neds to be pushed upto 90mg per day, or perhaps a different drug needs to be tried, as options to take with Phenelzine are limited.
Posted by DavidLa on August 25, 2008, at 22:19:20
In reply to Re: What OCD meds are safe.. Abilify?, posted by dcruik518 on August 19, 2008, at 9:33:54
> DavidLa,
>
> I take abilify for what some p-docs have considered a kind of OCD but others consider more like a nervous tic. I have trichotillimania, or compulsive hair pulling. The abilify totally wipes out the hair pulling compulsion. Which makes me suspect it would work well for other OCD compulsions.What dosage was effective for you? Any side effects?
Nardil actually increases my OCD-like symptoms, so increasing the dose is not an option. Not to mention the side effects at higher dosages get much worse.
This is the end of the thread.
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